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Doctor insights on: Germ Cell Tumor Testicular Cancer

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Extragonadal germ cell tumor?

Extragonadal germ cell tumor?

The gonads produce: Sperm in men (&testosterone) and eggs/ova in women (& estrogens), and these are also the sites of germ cell tumors. Outside the gonads, the mediastinum and brain (pineal) are the most common extragonadal sites. These are known to produce markers (hcg, alphafeto-protein) and responsve and curable with chemotherapy. Hope this helps. ...Read more

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Dr. Barry Rosen
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Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Testicular cancer: what is a non seminomous germ cell tumor?

Testicular cancer: what is a non seminomous germ cell tumor?

Potentially serious: A nonseminomatous germ cell tumor is a malignancy that has multiple origins within the testicle. It is less common, but potentially more serious, than seminomas of the testicle. Early and aggressive treatment is necessay and can lead to cure in many patients that present with limited disease. Systemic chemotherapy is now available for patients that present with advanced tumors. ...Read more

Dr. Liawaty Ho Dr. Ho
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Odds of germ cell cancer?

Dr. Liawaty Ho Dr. Ho
2 doctors agreed:
Odds of germ cell cancer?

Germ cell: Are you referring to testicular cancer? Or germ cell cancer of the ovary? The lifetime risk of developing testicular cancer is 1: 270 =0.37. http://www.cancer.org/cancer/cancerbasics/lifetime-probability-of-developing-or-dying-from-cancer. ...Read more

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With germ cell tumor that to deal with germ cell tumor cancer?

With germ cell tumor that to deal with germ cell tumor cancer?

Clarify, can be CA.: These can be cancer. These are tumors of germ cells which can be from the gonads, or ovary and testis, or from outside these areas and occur during embryonic development. These can be cancerous or non-cancerous. Prognosis varies. Some, like seminoma, have a very good prognosis. ...Read more

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Are kidney cancer cells different from breast cancer cells and lung cancer cells?

Are kidney cancer cells different from breast cancer cells and lung cancer cells?

Quite Different: These 3 different cancers are actually quite different. Under the microscope they look different, and the types of mutations they have are also different. As a result, the way the different cancers are treated are also different. Generally speaking for kidney cancer they would use targeted therapies or immunotherapies instead of chemotherapy or hormone therapy. ...Read more

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Has anyone cured extragonadal germ cell cancer?

Has anyone cured  extragonadal germ cell cancer?

Yes: This is treated by a medical oncologist and may be cured with appropriate therapy. ...Read more

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Is metastatic squamous cell carcinoma genetic?

Genetic component?: There could be genetic component to a squamous cell cancer, although the exact implications on treatment aren't known. Obviously if there is a strong family history of cancers, or if it strikes someone who is young and/or a non smoker/drinker i would suspect a strong genetic contribution. Without more details, it is hard to say with any certainty. ...Read more

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Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? carcinoid Neuroendocrine tumors?

Complicated question: Carcinoids are carcinomas, usually more slow growing than adenocarcinomas. For information in this topic you may consult this link: http://www.webmd.com/cancer/carcinoid-tumors#1 ...Read more

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Describe identification of tumorigenic breast cancer cells?

Describe identification of tumorigenic breast cancer cells?

Diagnosis?: Are you asking how breast cancer cells are found? Most breast cancer is detected by imaging (mammograms, ultrasound, or mri) suspicious areas are then biopsied either through the skin with a needle or through a small incision. ...Read more

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Can basal cell cancer spread?

Can basal cell cancer spread?

Yes, but unlikely: Basal cell cancers (bcc) are the most common type of cancer on the skin. While they can grow aggressively locally if neglected, they are very unlikely to spread elsewhere in the body. Most bccs can be treated with surgery, curretting, and certain ones can even be treated with a cream. Larger bccs and those in sensitive areas should be treatd by a fellowship trained mohs surgeon. ...Read more

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What is the incidence for extragonadal germ cell tumors?

Very low: Compared to the gonadal germ cell tumors. The most common locations are the mediastinum, the pineal gland in the brain and the abdomen. ...Read more

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What is extracranial germ cell tumor of childhood?

Rare family: This is a family of tumors that can be diagnosed by a pathologist (i suggest you get a consensus from 3 of us) that resemble to some degree the gametes and/or the cells of the unborn child. They run from totally benign to very malignant; thankfully today's treatment produces many good responses. ...Read more

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What is small cell carcinoma lung cancer with liver cancer stage 4?

What is small cell carcinoma lung cancer with liver cancer stage 4?

Bad situation: Small cell is a very bad cancer. Stage four is very advanced. Very poor prognosis at best-- usually months only. ...Read more

Dr. Liawaty Ho Dr. Ho
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Symptoms of prostate cancer metastasis?

Dr. Liawaty Ho Dr. Ho
5 doctors agreed:
Symptoms of prostate cancer metastasis?

Prostate cancer: The most common metastatic site would be bones-although it also can go to other sites- lymph glands, lung, liver etc.. Symptoms will depend on the location of metastases. Bone pain, fractures would be the symptoms of bony mets. If spread to the adjacent area such as bladder area- blood in urine, lower abdomen pain, prob wi/ urination, obstruction can happen. Weight loss, weakness are common too. ...Read more

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I'm concerned about prostate cancer metastasis. Where can prostate cancer spread?

I'm concerned about prostate cancer metastasis. Where can prostate cancer spread?

In theory, prostate cancer cells can spread anywhere in the body: In practice, though, most cases of prostate cancer metastasis occur in the lymph nodes and the bones. Prostate cancer metastasis occurs when cells break away from the tumor in the prostate. The cancer cells can travel through the lymphatic system or the bloodstream to other areas of the body. More commonly prostate cancer metastasis can occur in the: Bones, Lymph nodes, Lungs, Liver, Brain. Rare locations of prostate cancer metastasis include: Adrenal glands, Breasts, Eyes, Kidneys, Muscles, Pancreas, Salivary glands, Spleen. If you've been diagnosed with prostate cancer and you're concerned about prostate cancer metastasis, talk with your doctor about your risk of prostate cancer metastasis and your treatment options. ...Read more

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How is ovarian cancer different from metastatic ovarian cancer?

How is ovarian cancer different from metastatic ovarian cancer?

Related to spread: Metastatic refers to a cancer that has spread from the original site that it originated from to a more distant site in the body. For example, if a woman had ovarian cancer and it spread to the lungs then this would be consider metastatic disease. ...Read more

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What about neuroendocrine (islet cell tumors)?

What about neuroendocrine (islet cell tumors)?

Interesting tumor: Overally, neuroendocrine tumors are often capable of over-producing hormones that your body naturally makes. Islet cells are cells that are naturally present in the pancreas and produce a number of hormones, most notably insulin. Insulin helps you break down and digest sugars. Patients with an islet cell tumor can produce too much Insulin resulting in weight & gain and low blood sugars. ...Read more

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What is stage 3a germ cell cancer in males?

What is stage 3a germ cell cancer in males?

Germ Cell Tumors: Dominantly occur in testes and the medistinum in males, and the ovaries in females. Stage iii or 3 a does not meet testis staging, where where ajcc 6th ed calls 3 any metastasis. Usually germ cell tumors are divided between embryonal and yolk sac and teratoma, and then there are seminoma. All are highly curable in males. ...Read more

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Neoplasms (Definition)

"tumor" literally translates as "mass", so even a fresh bruise could be called a "tumor". Doctors use the term "neoplasm" (tranlates literally as new growth) to describe tumors that are abnormal growths of cells. These may be benign or malignant; "malignant" = cancer. In everyday usage, we use "tumor" ...Read more


Germ Cell (Definition)

Gamete. As often used in pathology, one of the diploid cells from which these may arise; for example, a germ cell tumor mimics the cells from which sperms and eggs arise. The future germ cells enter the embryo by a curious route and may also ...Read more