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Doctor insights on: Germ Cell

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Germ Cell (Overview)

Gamete. As often used in pathology, one of the diploid cells from which these may arise; for example, a germ cell tumor mimics the cells from which sperms and eggs arise. The future germ cells enter the embryo by a curious route and may also be called germ cells.


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What is the definition or description of: germ cell?

What is the definition or description of: germ cell?

Sperm or egg: Gamete. As often used in pathology, one of the diploid cells from which these may arise; for example, a germ cell tumor mimics the cells from which sperms and eggs arise. The future germ cells enter the embryo by a curious route and may also be called germ cells. ...Read more

Germ Cell (Overview)

Gamete. As often used in pathology, one of the diploid cells from which these may arise; for example, a germ cell tumor mimics the cells from which sperms and eggs arise. The future germ cells enter the embryo by a curious route and may also be called germ cells.


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What is the incidence for extragonadal germ cell tumors?

Very low: Compared to the gonadal germ cell tumors. The most common locations are the mediastinum, the pineal gland in the brain and the abdomen. ...Read more

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Living with Sickle Cell Disease (Checklist)

Keep doctor's appointments
Once
Go to lab appointments
Once
Keep oxygen up by maintaining low weight, no smoking
Once
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What treatments are for germ cell tumors?

Chemotherapy: I presume that you are talking about testicular cancers which are generally treated with chemotherapy. ...Read more

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Are mediastinal germ cell tumors known to be hereditary? I was cured, but my girlfriend is concerned if we were to have kids.

Germ cell tumors: These tumors are very rare and as such there isn' t enough information available to determine whether there is a genetic basis involved. ...Read more

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Odds of germ cell cancer?

Odds of germ cell cancer?

Germ cell: Are you referring to testicular cancer? Or germ cell cancer of the ovary? The lifetime risk of developing testicular cancer is 1: 270 =0.37. http://www.cancer.org/cancer/cancerbasics/lifetime-probability-of-developing-or-dying-from-cancer. ...Read more

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Extragonadal germ cell tumor?

The gonads produce: Sperm in men (&testosterone) and eggs/ova in women (& estrogens), and these are also the sites of germ cell tumors. Outside the gonads, the mediastinum and brain (pineal) are the most common extragonadal sites. These are known to produce markers (hcg, alphafeto-protein) and responsve and curable with chemotherapy. Hope this helps. ...Read more

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What is stage 3a germ cell cancer in males?

What is stage 3a germ cell cancer in males?

Germ Cell Tumors: Dominantly occur in testes and the medistinum in males, and the ovaries in females. Stage iii or 3 a does not meet testis staging, where where ajcc 6th ed calls 3 any metastasis. Usually germ cell tumors are divided between embryonal and yolk sac and teratoma, and then there are seminoma. All are highly curable in males. ...Read more

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Has anyone cured extragonadal germ cell cancer?

Has anyone cured  extragonadal germ cell cancer?

Yes: This is treated by a medical oncologist and may be cured with appropriate therapy. ...Read more

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How long can someone live with a germ cell cancer?

How long can someone live with a germ cell cancer?

For life!: Germ cell tumors come from the testicles, the ovaries, or other early cells. They can often be completely cured! in fact, germ cell tumors can be cured after they have spread to many places in the body, which is not true for other cancers. Treatment may require surgery, chemotherapy, and radiation. Ask your doctor about your progrnosis. Lance armstrong had a germ cell cancer...So don't give up! ...Read more

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Can adults develop extracranial germ cell tumors too?

Can adults develop extracranial germ cell tumors too?

Yes.: Adults can develop extracranial germ cell tumors. These can be either benign or malignant. Behavior of these tumors depends upon the location / the organ (site) in which the tumor develops and upon the microscopic and molecular-genetic features of the individual tumor. Hope that this helps. ...Read more

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Has anyone here heard of extragonadal germ cell cancer?

Has anyone here heard of extragonadal germ cell cancer?

Yes: Yes, sure.Extragonadal germinal cell tumors are rare tumors, represent 5-10% of all germ cell tumor, that predominantly affect young males.Characterized by their location on the midline from the pineal gland to the coccyx, (most common in mediastinum) . In egct, no evidence of a primary malignancy is present in testes or ovaries . Seminoma accounts for 30-40% and carries the best survival rates. ...Read more

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The organs like that, but is germ cell cancer particularly bad?

The organs like that, but is germ cell cancer particularly bad?

Treatable: For germ cell cancers excellent chemotherapeutic agents are available, prognosis is excellent compared to a decade ago, famous cyclist lou armstrong is the best example. He saved more lives than winning races, by publicizing his case and making people aware of testicular cancer for early detection. ...Read more

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How do I prepare my child for an appointment about a germ cell tumor?

How do I prepare my child for an appointment about a germ cell tumor?

Treating a growth: It depends of the age of your child and how clear the diagnose is by now. If there are symptoms associated with the "growth", explain that this appointment is with the purpose of making a plan to treat this growth, to help with the symptoms. You encourage simple and clear answers with every step. Allow your questions being answered first, so your child senses a peaceful and truthful interaction. ...Read more

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What number of divisions occur during meiosis and how many sperm are produced per germ cell?

Here are my take ...: As I still could remember from what I learned in residency, a germ cell will go through 6 times of division over a span of approximately74 days resulting in 148 sperms. Of course, you may surf the Internet. In reality, this Q is not practically and clinically relevant so I didn't look up for confirmation. ...Read more

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Germ cell cancer on spine, liver, ribs?

Germ cell cancer on spine, liver, ribs?

Could betreated: Simple explanation they are remanents of embryonic cells, now these tumor cells are in the spine, liver , ribs, origin could be from gonads ( testis or ovary ) or non gonadal . In spite of spread , due to excellent chemotherapeutic agents will assure reasonably good prognosis, cyclist lou armstrong is the best example. ...Read more

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What is extracranial germ cell tumor of childhood?

Rare family: This is a family of tumors that can be diagnosed by a pathologist (i suggest you get a consensus from 3 of us) that resemble to some degree the gametes and/or the cells of the unborn child. They run from totally benign to very malignant; thankfully today's treatment produces many good responses. ...Read more

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