Doctor insights on:
Gerd And Cancer Risk
PPI and cancer: We believe that chronic irritation of the lower part of the esophagus just before it empties into the stomach (gastric reflux) may play a big role in the development of esophageal cancer. PPI's decrease the amt of acid in the stomach and thus the irritation and thus may lower the risk of stomach cancer. ...Read moreSee 1 more doctor answer
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Treat the GERD: If the GERD is treated properly with antacids, there is very little risk of developing Barretts. There is very remote if any chance of developing Gastric Cancer. So youc an relax and take your PPIs as needed to keep the heart burn under full control. You may ahve to take PPIS for a long time. But you can get the Cancer fear out of your mind. You may need Upper endoscopy every 10 years to look fo ...Read more
Please help very anxious, will taking PPIs for hiatal hernia and gerd reduce the risk of developing Barrett's oesophagus?
Follow advice...: Many factors may contribute to the occurrence of Barrett's esophagus like GERD, smoking, regurgitation, etc., and PPIs may help ease GERD-related symptoms. So, it is logical to state PPIs may potentially decrease the risk of developing Barrettt's esophagus. But, how much may it help still remains unclear. Remember: Doc never cures anything, but help modify something to some degree with/without... ...Read more
Depends on type: For adenocarcinoma, the risk factors are mainly acid reflux, leading to barrett's metaplasia, and being male. The risk factors for squamous cell carcinoma include smoking, alcohol, radiation exposure, other head and neck cancers, caustic ingestion, a condition called achalasia, eating foods with nitrates, and conditions called chaga's disease and tylosis. ...Read moreSee 1 more doctor answer
Many things: >80% of lung cancer is caused by smoking. However never smokers (defined as <100 cigarettes in lifetime) can get smoking. Risk factors include radon exposure, second hand smoke, and genetic mutations such as egfr activating mutations. For more info: http://bit.Ly/ygfoko. ...Read moreSee 2 more doctor answers
Smoked foods?: The risk of gastric cancer has been associated with consumption of smoked and salted foods and lack of refrigeration. The widespread use of refrigeration has been cited as a reason for the decrease in the incidence of gastric cancer in the US since 1930. Several studies have demonstrated an association between Helicobacter pylori and gastric cancer. Common in Japan, Iceland, Chile & Costa Rica. ...Read moreSee 1 more doctor answer
Risk of acid reflux is barets esophgus but when acid is stopd then risk of bile into esophgus carries risk of cancer.This means risk with & w/o PPI?
Better: Quitting improves them. Work with family physician towards comprehensive wellness. It's important to understand there are numerous disease that smoking will increase risk. Per lung cancer, there are some online resources to help calculate risk: http://goo.Gl/divhj and http://goo.Gl/r9ita. ...Read moreSee 1 more doctor answer
Possible but unusual: Most likely lower esophageal adenocarcinoma is caused by gerd, which changes the lining of the lower esophagus into that of the stomach (barrett's) which is a precursor for adenocarcinoma. However, one could have squamous cell type without gerd. Best to review with your gastroenterologist. ...Read moreSee 1 more doctor answer
Does higher level of c reactive protein increase the risk of getting diseases like cardiovascular disease, colon cancer, and lung cancer?
Limited usefulness: C-reactive protein is very useful in making the diagnosis of a couple of uncommon illnesses, such as temporal arteritis, in which it is much elevated. It is neither sensitive nor specific for anything else, and especially, as a pathologist i'm unimpressed with it as a screen for any health risk -- it's neither sensitive nor specific, and generates useless worry. Live healthy ; forget it. ...Read more
While Chron's can: Have varied course, it can affect the entire gut. It's cousin, ulcerative colitis that affects the large bowel, is the cancer prone malady. Chron's, aka regional enteritis, can cause a great deal of misery, but it is not usually a cancer prone illness. ...Read moreSee 1 more doctor answer
Sometimes: There is a familial disorder known as lynch syndrome which increases both the risk of colon cancer and endometrial (uterine) cancer. About 5% of all colon cancers are caused by lynch syndrome. If a family has multiple cases of both colon and endometrial cancer or colon cancer under the age of 40, lynch syndrome should be considered. ...Read moreSee 1 more doctor answer