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Doctor insights on: Genomic Alterations Clarisure Cgh

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Tell me about genomic testing. Should I do it?

Tell me about genomic testing. Should I do it?

Depends: Your genes are one of the factors than can influence your health and disease. The usefulness of gene testing is still evolving. Your family history can help guide you as to how useful it may be for you. The most useful areas today are testing for recessive genes, risk analysis for certain diseases like cancer, and pharmacogenomics. Results can be confusing so counseling is important. ...Read more

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What's a good resource for trace elements and heavy metal toxicity?

What's a good resource for trace elements and heavy metal toxicity?

Be VERY careful: Most of the outfits offering "heavy metal testing" are scams, charging outrageous prices for"tests" intended to get you to buy their nutritional supplements, have your fillings removed, and generally suck you into a expensive racket. They exude warmth and this is the one thing that may make you feel better. ...Read more

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Is whipple's disease usually deadly?

Is whipple's disease usually deadly?

No, but must dx & rx: Whipples disease is a very rare condition, often found in middle age men, that is also called lipodystrophy. It a bacterial-caused disease that leads to malabsorption of mostly fats and certain sugars into the bloodstream. It will lead to nutritional deficiencies among other problems. Need rx with antibiotics, usually at least a year, herbs and supplements. If left untreated, it can be fatal. ...Read more

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Got gene tests from pathway genomics as part of research study. Are results relevant to my pcp? How should I present them?

Got gene tests from pathway genomics as part of research study. Are results relevant to my pcp? How should I present them?

Relevant - yes: Share them with the doc in advance so they can pre-read. Realize the vast majority of doctors graduated medical school well before the human genome was published, so they may be slow on the uptake. But even better, feel free to call pathway directly and speak with a counselor for free. Also, search out a doctor who is comfortable with the data. Pathway or 23andme can likely point you to docs. ...Read more

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What is nutritional genomics?

What is nutritional genomics?

Nutritional genomics: It is the study of how nutrition and genetic makeup work together. This incredibly interesting field covers many types of interactions: single gene mutations where a nutrient cannot be metabolized; genetic complexes that put a person at risk for increased chances of heart disease; and food substances that can cause cancer. These are just a few examples of this emerging field. ...Read more

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What do I need to know about my son's genomics. He is a donor child.?

What do I need to know about my son's genomics. He is a donor child.?

Helpful information: The family history is helpful when a disease with known genetic implications may be involved.Disorders like huntington's disease are worrisome since it only takes one gene for expression & a donor could pass it. Of lesser impact are polygene issues like heart defects, asthma & diabetes. Most donor centers screen the family history & reject problem donors.Some may or may not release their info. ...Read more

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What are genomics tests?

What are genomics tests?

Gene mutations: Your genes are one of the factors than can influence your health and disease. The usefulness of gene testing is still evolving. Your family history can help guide you as to how useful it may be for you. The most useful areas today are testing for recessive genes, risk analysis for certain diseases like cancer, and pharmacogenomics. Results can be confusing so counseling is important. ...Read more

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When should I have my child's genomics tested?

When should I have my child's genomics tested?

Test for what?: There is currently no recommended routing genetic testing. Only tests recommended are done during the newborn period and any other time only if there is a clear medical indication. ...Read more

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Tell me about genomic testing. Should I do it?

Depends: Your genes are one of the factors than can influence your health and disease. The usefulness of gene testing is still evolving. Your family history can help guide you as to how useful it may be for you. The most useful areas today are testing for recessive genes, risk analysis for certain diseases like cancer, and pharmacogenomics. Results can be confusing so counseling is important. ...Read more

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Can you tell me in genomics, what do im, pm, um, and em mean?

Can you tell me in genomics, what do im, pm, um, and em mean?

Drug metabolizers: CYP2C9 gene, part of the P450 system. Extensive metabolizers, intermediate metabolizers, poor metabolizers, ultra-poor metabolizers. ...Read more

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Is there a hormone that reverses all of the actions (inc. Genomic) of cortisol?

Is there a hormone that reverses all of the actions (inc. Genomic) of cortisol?

More importantly...: If your cortisol is high it means your body is responding to some sort of stress. It would be better if you could identify this stress and remove it from your internal or external environment. ...Read more

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I'm 36 and have 2 copies of APOE4 per Pathway Genomics. I have mild cognitive issues. What testing is appropriate that insurance will cover?

I'm 36 and have 2 copies of APOE4 per Pathway Genomics. I have mild cognitive issues. What testing is appropriate that insurance will cover?

Careful: Insurance ≠: issues. Typical larger issue is NMR-lipoproteins by Vantera Analyzer, the primary driver of arterial disease & strokes, along with ?ed BP. So optimize LDL to <400 nmol/L & large HDL to >9 umol/L by NMR along with HbA1c <5.0% & Systolic BP <120 mmHg. Also study the work of Leah Makley (more details later) ...Read more

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Is there a genomic test for ovarian cancer?

Is there a genomic test for ovarian cancer?

Yes: Many genes have been identified that may increase your risk of ovarian cancer from the normal <1% risk to a doubling or up to a 40% lifetime risk. The best validated gene is the brca gene. The new next generation sequencing technology can check for 19 genes at once that increase risk of breast, ovarian and uterine cancer. This may be helpful if you have a family history of ovarian cancer. ...Read more

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Got gene tests from pathway genomics as part of research study. Are results relevant to my pcp? How should I present them?

Relevant - yes: Share them with the doc in advance so they can pre-read. Realize the vast majority of doctors graduated medical school well before the human genome was published, so they may be slow on the uptake. But even better, feel free to call pathway directly and speak with a counselor for free. Also, search out a doctor who is comfortable with the data. Pathway or 23andme can likely point you to docs. ...Read more

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Can cdiff cause alterations in mental status?

Can cdiff cause alterations in mental status?

If severe enough: C diff colitis can result in sepsis, which can manifest as alterations in mental status. C diff colitis causing sepsis is life threatening. The current definition of sepsis is called qSOFA. You get 1 point each for low blood pressure, high respiratory rate, or altered mental status. A score of 2 or more means you have sepsis. https://en.wikipedia.org/wiki/SOFA_score#Quick_SOFA_Score ...Read more

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