Doctor insights on:
Genetic Testing After Miscarriage
Consultation first: Every couple can learn something from meeting with a clinical geneticist. They evaluate both family trees & can identify genetic issues you may be at risk for. With this information they can focus on which if any conditions to look for. There are in excess of 200 gene related defects they can identify, but there is no test that will identify all & many are studied only in a couple labs in the US. ...Read moreSee 2 more doctor answers
Prenatal testing for genetic problems may be done before or after conception. Testing for spina bifida or Down syndrome is done after a pregnancy is established. Besides the couples listed above, counseling and diagnosis are also recommended for mothers over the age of 35, and those who have received abnormal screening test results, such as alpha-fetoprotein (AFP). For more information about the alpha-fetoprotein test, and when and why you might have it, see alpha-fetoprotein. For those who may be at risk, genetic counseling and prenatal diagnosis are used to help ...Read more
Tissue testing after d&c showed up turners syndrome. What's the risk for future pregnancies. This was second early mc. Mother's age 32yrs ?
Yes: Check with your rei specialist for details, but all ovum donors would be asked to report a detailed family history and would be tested for common recessive disorders, such as cystic fibroisis. Many programs would also request more extensive testing including a panel of 100 such recessive diseases, including such problems as spinal muscular atrophy, the askenazi jewish panel, fragile x, & more. ...Read moreSee 1 more doctor answer
Does noninvasive prenatal testing(cfDNA )capture baby's genetic defects?Is amniocentesis better for more accurate results? Im 31&12 weeks pregnant.
Some and yes: The cf-DNA can detect many genetic anomalies but it is not 100% and when positive is usually confirmed by an amniocentesis for a full karyotype. The amniocentesis is the gold standard for detecting genetic anomalies . Sampling of the placental tissue _ ie: chorionic villus sampling would be comparable to an amniocentesis and can be performed earlier in the pregnancy. ...Read more
Why recommended to rule out anatomic, hormonal & chromosomal abnormalities first before doing antiphospholipid & autoimmune tests-2 early miscarriages?
First things first : Because they are more common.Get a more detailed answer ›
What prenatal tests recommended even after PGS tested embryo. History of 3 MCs With turner's & Trisomy 14, age 34.Need 2nd opinion from few docs pls. ?
Same tests: The curent recommendation is that patients who underwent preimplantation testing still undergo the usuall genetic testing during pregnancy. Your doctor can discuss options such as Sequential screening and cell free DNA testing. They may want to test for antiphospholipid antibodies based on your 3 miscarriages. ...Read more
See below: After 1 miscarriage, the chances don't change...Still around 5-10% depending on the study. ...Read more
Nope.: Genetic prenatal testing can detect many chromosomal or microscopic dna defects - but it cannot prevent birth defects! 2-4% of all newborns will have a minor or major birth defect and the vast majority of those have unknown genetic underpinnings at this time, although many of us are working to change that. Take Folic Acid 1-5 mg daily to prevent 75-95% of major neural/cardiac fetal anomalies! ...Read moreSee 2 more doctor answers
Is a noninvasive prenatal paternity bloodtest, done with blood from alleged fathers, cfdna and 317.000 genetic markers a reliable test?
3 MCs no live birth. 2 MCs turner's & trisomy14 in fetus. Parents karyotyping normal. What other genetic tests shld be done. Risk of abnormal child ?
Would a standard genetic test detect 22q11.2 deletion syndrome? My son had genetic testing done at 2 yo.
Standard genetic ?: There are thousands of genetic related tests I am aware of and each has its uses for specific cases. A simple chromosome study would not pick up this deletion.A high resolution study would likely find it in most specialty labs.Some also do a specific study using a genetic probe.This is a question best answered by the folks who did the study in question. ...Read more
Yes: BRCA testing can be performed from either blood or saliva. A significant amount of DNA needs to be present for adequate testing so most companies require more than a finger stick blood draw. Usually a single blood tube containing 3 ccs of blood is adequate ...Read moreSee 2 more doctor answers
Will a vanishing twin (lost at 7 weeks) affect first trimester downs syndrome testing with blood test and ultrasound?
Vanishing twin: No, it would not affect your test result. Ultrasound would show it for a while, but the developing twin will eventually grow big enough to hide it from view. ...Read more
Is HIV antibodies test conclusive at 3 months after exposure?and is DNA PCR test conclusive after 45 days after exposure?
HIV Infection: Technically speaking PCR is conclusive at the time of infection. The moment HIV enters the human blood stream it explodes. Viral tires go into the multiple millions. So testing by PCR would easily catch this. The problem is..it is not intended to be used as a screening test due to the cost. So..the antibody test at 3 months is good..but 6 months out is needed to be conclusive in my opinion. ...Read more
Genetic testing: They will ask you a lot of questions about your family and the fathers family, they will assess the risk, and they will do a test- can now be done often with mucus but may be blood test ...Read more
Positive pregnancy test 10 weeks after full term delivery: new pregnancy or residual pregnancy hormone from previous pregnancy?
From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more