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Doctor insights on: Genetic Muscle Nerve Degeneration Sma Treated

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If I have a high positive ANA (1:640) speckled, nucleolar and low positive SMA (1:40), what further tests do I need to do? (Negative SS-A, SS-B, Smith, RNP, SCL-70, Anti Jo Abs)

If I have a high positive ANA (1:640) speckled, nucleolar and low positive SMA (1:40), what further tests do I need to do?  (Negative SS-A, SS-B, Smith, RNP, SCL-70, Anti Jo Abs)

? anti dsDNA: You've probably already had these more basic tests: complete blood count, sedimentation rate, C-reactive protein, urinalysis & rheumatoid factor. It appears to me that the ANA results with slight positive anti-Smith may suggest lupus; you need an antibody to double-stranded DNA (anti dsDNA) which is very specific & somewhat sensitive for lupus.All this needs to be correlated by your doc/specialist ...Read more

Genetic (Definition)

From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more


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How is a genetic muscle or nerve degeneration (md, sma) process treated or prevented-current; future?

How is a genetic muscle or nerve degeneration (md, sma) process treated or prevented-current; future?

Gene therapy: Though many things have been tried, really not anything that has been proven to do much yet. Given that sma is a genetic disorder with well known muscle protein abnormalities, it seems a great target for gene therapy type treatments, which are being researched. ...Read more

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Do you know are chiropractors worth going to for general nerve degeneration?

Not really: For any degenerative nerve issues. Neurodegenerative diseases are something that should be handled by a neurologist or physiatrist. ...Read more

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Please answer! what vitamins / herbs / holistic approach would help with nerve degeneration / numbness ?

B vits, ALA and ect.: This answer could vary depending on what's causing the nerve degeneration but b vitamins are great for nerve health, especially vit. B 12. Alpha lipoic acid may help neuropathy and numbness. It is always best to consult with your doctor before you consider taking supplements. ...Read more

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Any recommended vitamins / herbs / holistic approach that can help with nerve degeneration / numbness ?

Vitamins : Vitamin b 6 i believe is the most well- known holistic remedy out there in the "vitamin" group. Supplements like acetyl-l-carnithine have been shown to reduce peripheral neuropathy pain and speed up healing of peripheral nerves. Other chinese herbs have also been implicated as beneficial. ...Read more

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What is cacosmia and what is its relation to deamination and nerve degeneration .And can these two conditions cause this.Explain the relation with brain and mood disorders?

What is cacosmia and what is its relation to deamination and nerve degeneration .And can these two conditions cause this.Explain the relation with brain and mood disorders?

Cacosmia: The imagining of unpleasant odors, particularly putrefactive odors, an unpleasant phantosmia.Psychiatric etiologies for olfactory distortion can exist with schizophrenia, alcoholic psychosis, depression and olfactory reference syndrome). Also been observed with epilepsy. This can also occur due to peripheral damage to the olfactory system. ...Read more

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A neighbor child has SMA (spinal muscular atrophy). Is this a genetic disease?

Yes: It's an autosomal recessive disease. That means that it takes a copy of the defective gene from each parent. Most of the time the parents of a child with sma are carriers, meaning they only have one copy of the defective gene. It is not contagious. ...Read more

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What are the genetics of sma?

What are the genetics of sma?

More than one type: Spinal muscular atrophy of infants, before the gene was identified, was called Werdnig-Hoffman disease. Pitiful-we always looked at the tongues of floppy babies hoping it wasn't fasciculating. No treatment, breathing muscles progressively weakened, resulting in suffocation. 1 chance in 4 of recurrence-maybe. 2% were mew mutations. Kugleberg-Weilander disease had onset after 12 mo. Now 7 forms ...Read more

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Problem for 6yrs. Muscle nerve pain in legs back. Hard to walk stand sit for long times. My dr says muscle degeneration. I want 2nd opinion.

Specialist: Have you seen a specialist? I am sure you would have had an MRI by now to see if there is nerve compression or stenosis. Sometimes these symptoms cannot be cured, but need to be managed. I am not sure about muscle degeneration. They may mean weakness and reduction in core stability. An EMG may help with the diagnosis. I would see a Physiatrist or Neurologist for 2nd opinion. ...Read more

Nerve (Definition)

The brain and spinal cord communicates with what is occurring in the internal organs and limbs by nerve fibers where are like electrical wires with insulation (myelin) and the "copper" (axon). Within brain and spinal cord these nerves connect to other nerves via synapses on both axons and dendrites. A nerve can carry information regarding sensations, and ...Read more


Muscle (Definition)

It is a body tissue that has the ability to contract. It shortens and generates force. It relaxes and returns to its original length. Muscles move joints, stabilize the body, move air and food through the organs, act as valves for bladder, bowel and other organs. They control movement of the eyes. They help us express ourselves by changing the shape of our ...Read more