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Doctor insights on: Genetic Impact Of Ivf Babies

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Does conventional ivf increase risk of genetic defect of baby conceived?

Does conventional ivf increase risk of genetic defect of baby conceived?

IVF & genetic defect: There are genetic causes of infertility that could be passed on to the baby. Otherwise I don't think there is enough data to make conclusions - my opinion. ...Read more

Genetic (Definition)

From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more


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Can MRI effect the development of sperm cells or impact sperm in anyway, pre-pregnancy that could contribute to chromosomal translocation?

Can MRI effect the development of sperm cells or impact sperm in anyway, pre-pregnancy that could contribute to chromosomal translocation?

No: I am unaware of any evidence in the scientific literature that a standard diagnostic MRI has any adverse effect on sperm, developing sperm, or on a person who is pregnant or the fetus. The literature suggests that the strength of the mr field at diagnostic levels does not affect dna synthesis, cell cycle, or proliferation kinetics in a fetus. ...Read more

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Will every triplet or twin in identical births have the same developmental disability?

Will every triplet or twin in identical births have the same developmental disability?

Probably not: Developmental delay/disabilities have many causes, most of which are not genetic. If you are known to carry a genetic disease associated with developmental disability, testing can usually be performed on each fetus individually while still in the uterus. If you are thought to have identical (monozygotic) twins or triplets, then they would all share identical genes. ...Read more

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Will art or IVF (in vitro fertilization) cause any birth defects in the baby?

Will art or IVF (in vitro fertilization) cause any birth defects in the baby?

Not likely.: See recent impactful publcation in the new england journal of medicine [n engl j med. 2012 may 10;366(19):1803-13. Epub 2012 may 5]. The increased risk of birth defects associated with ivf was no longer significant after adjustment for parental factors. The risk of birth defects associated with icsi remained increased after multivariate adjustment. ...Read more

Dr. Amr Azim Dr. Azim
2 doctors agreed:
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What are the economic impacts on couples in vitro fertilization?

Dr. Amr Azim Dr. Azim
2 doctors agreed:
What are the economic impacts on couples in vitro fertilization?

Depends: 1. Insurance coverage or the whole process, part, medication, how many trials...2. Geography prices maybe different in different parts of the country 3. Requirement for additional procedures e.g. Surgical sperm harvest or genetic diagnosis of the embryos 4. Cost for undesired effects effects of treatment e.G multiple pregnancy. Based on these and many factors the economic impact could be vary. ...Read more

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Will every triplet or twin in identical births have the same learning disability?

Will every triplet or twin in identical births have the same learning disability?

No: Identical twins share some disorders to a high degree (e.g., adhd, bipolar disorder), but learning disabilities are not a specific disorder, rather a heterogenous grouping of brain dysfunctions that may affect learning. Multiples are at higher risk for ld's because of shortened gestation, increased incidence of neonatal problems, & decreased intrauterine nutrition. ...Read more

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Can a parents pot smoking affect the child (fetus) from conception?

Can a parents pot smoking affect the child (fetus) from conception?

Unclear.: Marijuana use has not been conclusively linked to adverse fetal/neonatal outcomes, however it remains illegal throughout most of the world and can cause maternal depression/psychosis with dire sequelae. It should not be used as antiemetic - other fda approved medications are safer and effective. ...Read more

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3 MCs no live birth. 2 MCs turner's & trisomy14 in fetus. Parents karyotyping normal. What other genetic tests shld be done. Risk of abnormal child ?

3 MCs no live birth. 2 MCs turner's & trisomy14 in fetus. Parents karyotyping normal. What other genetic tests shld be done. Risk of abnormal child ?

No need extra tests: No need for further tests before pregnancy since the parents chromosomes are normal. For early piece of mind you can consider early non-invasive genetic screening in early pregnancy. ...Read more

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What is the average lifespan of baby born with trisomy 13, patau syndrome?

What is the average lifespan of baby born with trisomy 13, patau syndrome?

Days/weeks.: Stillbirth (see picture) is very common. Of liveborns, 80% of affected infants die within the first month of life; only 5% survive the first six months. Severe intellectual disability, seizures, and failure to thrive are noticeable in survivors over 1 year of age. No interventions for fetal benefit are ethically justifiable during pregnancy (no cesarean section, no fetal monitoring indicated). ...Read more

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Can spina bifida have any genetic links, or is it all environmental or chance factors during development?

Can spina bifida have any genetic links, or is it all environmental or chance factors during development?

Spina bifida: There can be a strong genetic link meaning that a parent has spina bifida then a child is at a higher risk of getting the disorder. Prenatal counseling is key here as the physician can go over medications that might need to be taken to prevent spina bifida such as folic acid ...Read more

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What is the impact of maternal cocaine addiction on baby's motor development?

What is the impact of maternal cocaine addiction on baby's motor development?

Not good: Maternal Cocaine addiction can lead to microcephaly (small head) and growth retardation in infants. Cocaine may also interfere with maternal-infant bonding, as some research shows the mothers are less flexible, less engaged, and have shorter feeding sessions than other mothers with newborns. Even at 2 years of age, the infants show deficiencies in both fine and gross motor development. ...Read more

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3 early MCs & chromosomal abnrml in all fetuses (no birth), is karyotyping of parents the only genetic testing tht can be done? Names of any other pls

3 early MCs & chromosomal abnrml in all fetuses (no birth), is karyotyping of parents the only genetic testing tht can be done? Names of any other pls

It's the starting pt: Parent study comes first.A person can appear normal if they carry all the proper chromosome material but with part belonging to one chromosome swapped with another.(ie, part of a #15 is on #21) When fertilization occurs, the fetus may get part of the mistake and not the other & be defective.Some of these have a partial chance of normal birth, some would always end up a defect.See a geneticist. ...Read more

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Can maternal diet during pregnancy influence offspring obesity risk?

Can maternal diet during pregnancy influence offspring obesity risk?

Yes! Via Epigenetics: Epigenetic changes are changes to the child's dna while still a fetus. Tehse changes are induced by the maternal diet. Increasingly epigenetic changes are being implicated in a host of common diseases occuring in offspring. These changes in the babies dna that do not involve changing the dna sequence but rather modify gene expression in children. ...Read more

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Which stage in human fertilisation/conception/pregnancy period does susceptibility to environmental factors that may contribute/cause defects start?

Which stage in human fertilisation/conception/pregnancy period does susceptibility to environmental factors that may contribute/cause defects start?

Before conception: The woman is born with all the eggs she will ever have and they mature over her lifetime until either released or lost.All exposure to chemicals/radiation/illnesses during a woman's life impact the egg quality.Once released to conception, the environmental influences on outcome are continuous.Some are time specific (thalidomide-5-7 wks) some are continuous (alcohol). ...Read more

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What is the pregnancy success rate of d5 xfer of 8 cell embryo, if D3 biopsy showed normal xx genetics. Also, did D3 biopsy affect embryo growth rate?

What is the pregnancy success rate of d5 xfer of 8 cell embryo, if D3 biopsy showed normal xx genetics. Also, did D3 biopsy affect embryo growth rate?

Ask specialist: This is a question best directed to your infertility specialist. Unfortunately those of us who are general practitioners and general ob/gyns don't have these statistics. Didn't want you to think we were ignoring you! good luck! ...Read more

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In north america when are obs doing blood vs genetic amnio tests on babies?

In north america when are obs doing blood vs genetic amnio tests on babies?

Screening vs confirm: Blood screening is a relatively non invasive way to get information on significant problems but by definition it is screening. Screening is an effort to narrow down the list of people that need a specific confirmatory test.By example, for every 1000 screened, 10 may be positive, and offered the amnio to find 1 true positive. An amnio is more invasive & risky but gives more definitive results. ...Read more

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Dr. Scott Keith
3 doctors shared insights

Ivf (Definition)

In vitro fertilization is an assisted reproductive technology. Ivf is a procedure used to treat fertility problems and assist with the conception of a child. During ivf mature eggs are retrieved from the ovaries and fertilized by sperm in a lab. A few days later, the fertilized egg (embryo) or eggs are implanted into the uterus. One cycle of in vitro fertilization ...Read more