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Doctor insights on: Genetic Brain Disorders Degenerative Nerve Diseases

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Dr. Richard Roberts
26 doctors shared insights

Genetic Brain Disorders (Definition)

Genetic brain disorder is a condition in which a person has a problem in the brain, related to a defect or mutation in his genes (DNA). Some conditions have symptoms in infancy, some appear gradually as a child grows, while other conditions show up in adulthood. These disorders include problems forming nerve cell connections, problems handling nutrients such as amino acids, problems getting waste material out ...Read more


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Is there research into any genetic, autoimmune or other condition that links nerve sheath disorders (tarlov cysts, nerve sheath tumor) with autoimmune hypophysitis targeting acth cells? Ctla-4 gene?

Is there research into any genetic, autoimmune or other condition that links nerve sheath disorders (tarlov cysts, nerve sheath tumor) with autoimmune hypophysitis targeting acth cells? Ctla-4 gene?

None that I find: I cannot locate any literature on the two conditions being studied simultaneously. Perhaps one of my more research savvy colleagues here will come up with something . Great question by the way. ...Read more

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How come wilson's disease (hepatolenticular degeneration) considered a genetic disorder?

How come wilson's disease (hepatolenticular degeneration) considered a genetic disorder?

Because it is: No disrespect is intended. Two defective copies of the gene atp7b, one from each carrier parent, renders the person incapable of unloading copper from cells that need to lose it. ...Read more

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What is progressive neuro-degenerative disease or any neuro-degenerative or atrophy cerebellar diseases or mental diseases?

What is progressive neuro-degenerative disease or any neuro-degenerative or atrophy cerebellar diseases or mental diseases?

Example: Neurodegenerative illnesses that affect the cerebellum may be the different forms of multiple system atrophy, such as OPCA. Other neurodegenerative illnesses (that do not affect the cerebellum) include Alzheimers, Parkinsons, and ALS. ...Read more

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Is there any degenerative brain diseases caused by liver disease?

Is there any degenerative brain diseases caused by liver disease?

Yes: Chronic poorly controlled liver disease can lead to a condition of brain injury called hepatocerebral degneration. This is not to be confused with the delirum that is seen with liver failure and is reversible ( hepatic encephalopathy). Hepatocerebral degeneration is a less reversible problem seen after years of advanced liver disease and has features like parkinson's disease, . ...Read more

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Is motor neurone disease different from locked-in syndrome?

Is motor neurone disease different from locked-in syndrome?

Very different: Locked in syndrome is usually the result of an injury to the brainstem that results in a loss of communication between the brain and the spinal cord. Motor neuron disease is a progressive degenerative process that affects the nerve cells that carry signals from the brain to the muscles that allow us to move. The most well known example of this is amyotrophic lateral sclerosis. ...Read more

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Are brain damages symptoms of huntington's disease?

Are brain damages symptoms of huntington's disease?

Huntigton's chorea: Huntigton's chorea is a specific disease that happens usually in the 40's secondary to a damage or regression of a specific area of the brain. ...Read more

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Can brain trauma cause autism spectrum disorder?

Can brain trauma cause autism spectrum disorder?

No: Head trauma can produce a variety of behavioral and cognitive changes, but there is no association with autism spectrum. ...Read more

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Doctors, what are the genetic links with MS and motor neurone disease (als)?

Doctors, what are the genetic links with MS and motor neurone disease (als)?

None : Als and ms are completely different disorders, and have no known common genetic profiles. ...Read more

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Can diabetes cause peripheral nerve disorders?

Can diabetes cause peripheral nerve disorders?

YES!: Yes! diabetes can be a very seriously disease - especially if not monitored closely and treated aggressively. High sugars often lead to nerve damage in the arms/legs that result in symptoms known as peripheral neuropathy that results in a stocking/glove like sensation of numbness and sometimes even what is referred to as neuropathic pain. Other disorders can also cause peripheral neuropathy. ...Read more

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Is cerbral palsy an inherited disorder?

Is cerbral palsy  an inherited  disorder?

No: Cerebral palsy is a termedreserved for perinatal events (i.e. Just before , during and just after the birth) that cause damage to the central nervous system. ...Read more

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Could strong antipsychotics cause neurons damage and result in demyelinating disease?

Could strong antipsychotics cause neurons damage and result in demyelinating disease?

Antipsychotics: Demyelinating disease is generally autoimmune in nature -- different from the effects of antipsychotic medications. In fact some research indicates that quetiapine may protect against demyelination. http://www.plosone.org/article/info%3adoi%2f10.1371%2fjournal.pone.0042746 nevertheless, long-term use of some antipsychotic agents can affect neuronal function -- just differently. ...Read more

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Can hashimoto's disease cause brain demyelinations ?

Can hashimoto's disease cause brain demyelinations ?

No: No, Hashimoto's does not cause brain demyelinations. Hashimoto's is an autoimmune thyroid dysfunction which will eventually cause hypothyroidism. During initial stage of Hashimoto's, thyroid function may remain normal or transiently elevated with self resolution. But in long term, most patient with Hashimoto's will develop hypothyroidism requiring thyroid hormone replacement ...Read more

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What diseases affect trigeminal nerve?

What diseases affect trigeminal nerve?

Numb face: May relate to Trigeminal nerve involvement, such as Neuropathy from excess alcohol, Diabetes, vitamin deficiency, electrolyte imbalance, MS, Trauma, Migraines, Shingles, Focal seizures, Hypothyroidism, Psychogenic, or Iatrogenic (unknown causes). ...Read more

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What can cause brain demyelination besides a demyelinating disease?

What can cause brain demyelination besides a demyelinating disease?

Several: There are hereditary problems called leukodystrophies, toxins such as glue sniffing can damage brain myelin, paraneoplastic events associated with cancers can have some effect, and of course ms as the best known cause. But sometimes, other disorders seem similar and can masquerade. ...Read more

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Are mitochondrial diseases considered metabolic disorders?

Are mitochondrial diseases considered metabolic disorders?

No: no, mitochondrial diseases related to certain internal cellular issues and their discombobulation's. Metabolic diseases include for the most part diabetes, obesity, Dysmetabolic syndrome, which are a separate type of disease process than internal internal cellular constituents such as mitochondria ...Read more

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Can a concussion cause the nerve disorder reflex neurovascular dystrophy?

Can a concussion cause the nerve disorder reflex neurovascular dystrophy?

See below: I believe you mean reflex sympathetic dystrophy which is an old term and has been replaced by the term chronic regional pain syndrome. I have not seen a concussion do this. ...Read more

Dr. MARIE DELCAMBRE
18 doctors shared insights

Degenerative Nerve Diseases (Definition)

One type of degenerative nerve disease is when the sheath around the actual nerve fibers deteriorated, thus dramatically slowing the impulses traveling down the axon of the nerve. Other types include the development of inclusions within the nerve body itself damaging its ability to function. Also there are diseases wherein the glial support cells in the brain fall ...Read more


Genetic (Definition)

From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more