Doctor insights on:
Gene Therapy For Color Blindness
Why not: Color deficiency, usually in males, is because of a defect on the sex chromosome (the x) which is unchecked by the y (male) chromosome. If you have this, none of your children will be color deficient because your male children get a y from you and your deficient x goes to your daughter whose mother is undoubtedly color normal. Color deficiency is not a particularly big handicap anyway. ...Read moreSee 1 more doctor answer
From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more
Ask your dad: Most people with color-blindedness function completely normally with regard to visual activiies. They just have some difficulty telling some colors apart. For example, greens and browns tend to look the same to them. ...Read more
No one in my family has the gene that causes color blindness and yet I have it. How is this possible?
X-linked: The most common colorblindedness is an x-linked trait. That means it occurs almost exclusively in males and is passed to them from a defect x from their mothers. Your mother could have gotten this gene from her mother. In this case, there would be no relatives with it. Ps. Ask your mother's father if he is color-blind. ...Read more
Why am i color blind? What is the cause of color blindness? No one in my family has the gene that causes color blindness.
Blame your Mom: If you have red-green color deficiency, then you carry a defective x-chromosome which you got from your mom (i assume you are a male). Your mom was a carrier so she was color normal and you had a 50% chance of getting the abnormal x from her. So in fact someone in your family, mom, had the gene. ...Read moreSee 1 more doctor answer
Red-green color blindness is caused by an x-linked recessive gene. In a family, the mother is a carrier of this gene while the father does not have the gene. What are the possible effects on their children?
None: Most color deficiency is inherited and suggested means such as a red contact lens over one eye merely shift the axis of color confusion to another pattern. Color blindness can be acquired in severe retinal disease like advanced diabetes and also optic nerve disease. Improvement is possible here if the underlying disease can be treated. ...Read more
What are you asking?: Can you clarify? Genetic testing for DNA isn't subject to much in the way of outside influences. Genetic work on colorblindness is available but we're not sure what to do with the data. The former is life-and-death. The latter is perhaps a target for gene therapy that will give fullcolor vision to those who haven't enjoyed it. ...Read more
1.What is color blindness change in protein?
2..What is the change in the DNA?
3.How does the change in DNA cause the change in the protein?
Central dogma bio: There are a myriad of color blindness types that have identified genetic causes. Hence, answering these questions would be speculation at best. If you want to understand the general paradigm of translation, suggest this: http://www.csun.edu/~cmalone/pdf360/Ch14-1gen%20code.pdf ...Read more
I have to do a genetic disorder report for class and was debating between color blindness and hemophilia. What are your opinions?
Both interesting: These are both fascinating diseases and the subject of much inquiry. Look on wikipedia and you will find much to talk about. The issues are quite different but the underpinning for each is genetic. The hemophilia has had impacts on history such as the family of queen victoria. Color deficiency has caused some famous accidents. Have fun. ...Read more
By replacing defect: Gene therapy is the use of genes for therapeutic effect. The original studies with gene therapy were for corrective gene therapy. To illustrate, patients with severe combined immunodefeciency were born with a mutation in the ada gene. The original gene therapy trial, engineered a virus that was used to infect bone marrow of children with this disorder. The normal gene corrected the disorder. ...Read more
No: Someone with down syndrome has an entire extra chromosome 21, this is incorporated into every single cell in the entire body, and causes creation of abnormal cell proteins and function. You cannot just pull out an entire chromosome - we are nowhere near that type of genetic therapy yet. Focus instead on what wonderful, full-loving people those with that extra chromosome are and enjoy them! ...Read moreSee 1 more doctor answer
Ophthalmologist prefer to use the term color deficit as blindness conveys other meanings. Lowered color perception can be inherited (many forms), can result from advanced loss of retinal cells, inherited retinal disease, and some forms occur due to CNS injury. There are excellent tests for the various types and they can be functionally ...Read more
Vision impairment and blindness are conditions in which a person cannot see well or see at all, even with glasses or contact lenses. If a person's best vision (with correction) out of either eye is only 20/70 - 20/200, he is impaired. If he can see no better than 20/200 or his visual field is no more than 20 degrees (severe "tunnel" vision), ...Read more