Doctor insights on:
Gene Associated Asthma
Difficult call: At present there have been some associations made between certain genes and diseases like asthma. However, the actual strength of this relationship has not been as concrete as we would like. AS far as the number, the association is not a single gene but quite a few making it difficult to pin down the culprit gene(s). Check U. of Pittsburgh, I hear they're doing a lot of work in this area. ...Read more
From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more
Hard to say: Though there seems to be a family link, the specific genes involved have really not been identified. Indeed, there may be many genetic links involved so pinpointing exactly which ones are involved may be down the road. ...Read more
Quite a few: Quite a number of genes which are know to interact to cause asthma have been identified. However, the end is not yet here. Links between seemingly unrelated genes have been noted. So we have a situation where any number of genes can be implicated but there is still more research to be done. The human genome is a very big, complex thing. ...Read more
Is it yet known what genes make one likely to get asthma? Are some genetic mutations known and can be tested for?
Phenotypes of Asthma: There are particular chromosomes noted for being associated with the asthma genotype but this does not mean they are a part of the asthma phenotype (genes displaying the disease). There is no testing except for symptoms and pulmonary function testing (including direct and indirect provocation testing) to determine asthma. ...Read more
Can u have atypical cystic fibrosis if u have asthma, severe pancreas involvement & CFTR m470v? Report indicates a 2nd gene may be rare or unknown
Maybe: Surprisingly, M470V is a common variation. Studies have shown 50% of the population has this mutation and actually less likely to cause CF. Most individuals with CF and carry M470V have some other hidden etiology that is the cause, rather than M470V. Genetic expression may be variable and so will be the clinical manifestations. Speak with your doc and a geneticist for specific information. ...Read more
Yes: Depending on which study is read, if one parent has asthma, there is a 25-40% chance that the children will have some form of it; if both parents have asthma, then there is a 60-80% chance that the children will have it. This suggests that there is a very strong genetic component to asthma but it is not the only factor. ...Read more
Sometimes: Allergic asthma is considered an inheritable condition -- meaning it can be genetic. But not all children of a mother or father with asthma will develop asthma themselves. There is a great deal of research ongoing to determine the influence of genetics vs. The environment on the development of asthma. ...Read more
Difficult to answer: Most asthma that starts in childhood can be linked to allergies. As we mature, other "triggers" may come into play such as occupational triggers (dust from manufacturing or fumes), pollution, etc. Though it sometimes can be difficult to put a finger on the cause, the treatments are usually the same- rescue inhalers and controllers (if necessary). Getting tested is always the best thing to do. ...Read more
Reliever/Preventer: This is a big topic. Most people only get symptoms every now and again (e.g. when they get a cold or exposed to dust) and their asthma will respond to a reliever like salbutamol (ventolin). Others get regular symptoms that require a preventer (there are various inhalers but most contain a low dose steroid). Have a look at this http://www.asthma.org.nz/resources/ ...Read more
Many causes 4 asthma: Asthma is a chronic inflammatory disease of the airways caused by both inherited and environmental factors. It doesn't spread like infections but develops in patients when inflammation leads to spasm of muscles around the windpipe and the airways become hypersensitive. Many factors trigger asthma, including allergies, respiratory infections, weather changes, irritants, exercise, and acid reflux. ...Read more
No: Asthma can't be cured, but its symptoms can be controlled. Prevention and long-term control are key in stopping asthma attacks before they start. Treatment usually involves learning to recognize your triggers and taking steps to avoid them, and tracking your breathing to make sure your daily asthma medications are keeping symptoms under control. In case of an asthma flare-up, you may need to use a. ...Read more
You don't: Asthma is a chronic condition of increased small airway reactions. There are genetic and environmental factors that persist throughout life, usually becoming evident in childhood. One learns to live with their asthma & present medications offer a near normal existence to most. There is no cure, there are programs that promote stability & reduced flare-ups through early recognition of problems. ...Read more
Fight genetics!: That's right. 50% of asthma risk you get from your parents. If you choose ones with allergies or asthma you are already at high risk. Tell your parents not to smoke, especially when mom is pregnant with you. Tell them to get a dog and a cat before your birth. That helps. Don't live near roads with heavy diesel traffic. Avoid wood smoke & damp homes. Get exercise, sunshine & eat lots of fish. ...Read more
get to the root:
The first thing is to be tested for your asthma. It is a simple test called spirometry. This, and your history, will permit the physician to make a proper diagnosis and recommend treatment. If you know now what things trigger an attack, either get rid of them (rugs, etc) or try to avoid contact (cats and dogs).
Remember, get tested first.
Good luck. ...Read more
Find out what:
Your "triggers" are...allergies/stress/environmental issues and find a good PULMONOLOGIST or ALLERGIST to help you design a medication program best for you! (Rescue inhalers, ongoing medications etc Some skin testing may be necessary! Start with your Primary Care Physician for a Referral
Hope this helps!
Dr Z ...Read more
see answer: Stop smoking and avoid second hand smoke, if you are overweight, than weight loss with a good exercise program and diet is recommended. Avoid triggers that may exacerbate your symptoms. Some people with asthma may have a genetic component and will simply need inhalers and meds to help with the disease. Best wishes. ...Read more
Symptoms, testing: Asthma is a respiratory condition diagnosed by compatible symptoms in a person who demonstrates airway obstruction on a breathing test that improves after a medication to open airways (albuterol). If symptoms are suggestive (chronic cough, wheezing, shortness of breath, typically worse at night) and criteria are met on a breathing test, then asthma can be definitively diagnosed. ...Read more
If your "triggers" are allergy induced-- remove or minimize as many as possible. If exercise induced, talk to your physician about pre-treatment. Pollution and occupational induced asthma should also be discussed. Make sure you also have your rescue inhaler with you and if you use a controller, do not skip any doses.
Good luck. ...Read more
Asthma can affect people to a varying degree for their whole life, although many children grow out of it.
Treatment is aimed at relieving symptoms during a flare & preventing how often the symptoms occur.
Broadly, there are 2 types of inhalers: Relievers (usually blue) and Preventers (orange, purple, red, brown or green).
More info? See 'Asthma Relievers' or 'Asthma Preventers' ...Read more
1. Identify and avoid asthma triggers (this may be allergic, irritant, ge reflux, sinus, colds, cold air, etc)
2. If persistent asthma, a daily controller medication like inhaled steroid medication is most effective. Many other meds as well.
3. Influenza vaccine annually and pneumonia vaccine
4. Monitor symptoms (sometimes peak flows) and have a written asthma action plan to follow during an attack. ...Read more
Unfortunately no: But the good news is that it can be controlled and you can lead a completely normal lifestyle, several Olympic medalists were asthmatic, treatments currently available helps managing the disease and controlling it to great extent, you need to keep follow up with your allergist/asthma specialist, and keep taking medicines as prescribed, good luck ...Read more
Yes if uncontrolled: In an asthma attack the muscles surrounding the bronchial tubes go into spasm in response to irritation. Trying to push air through the smaller pipes can cause fatigue and respiratory failure. Identifying your asthma triggers that set off attacks and working with your doctor to find the best combination of treatment to prevent attacks and an action plan to treat such attacks can control this risk. ...Read more
Treatment...: Asthma can be treated but not cured. Typical treatment includes bronchodilator and steroid inhalers. Other treatments depend on the specific symptoms present. Most asthmatics can be rendered symptom-free between exacerbations. If you smoke, quitting is necessary to decrease airway inflammation. See your doctor for treatment, especially if you still have symptoms. ...Read more