Doctor insights on:
Gene Associated Asthma
Difficult call: At present there have been some associations made between certain genes and diseases like asthma. However, the actual strength of this relationship has not been as concrete as we would like. AS far as the number, the association is not a single gene but quite a few making it difficult to pin down the culprit gene(s). Check U. of Pittsburgh, I hear they're doing a lot of work in this area. ...Read more
From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more
Hard to say: Though there seems to be a family link, the specific genes involved have really not been identified. Indeed there may be many genetic links involved so pinpointing exactly which ones are involved may be down the road. ...Read more
Quite a few: Quite a number of genes which are know to interact to cause asthma have been identified. However, the end is not yet here. Links between seemingly unrelated genes have been noted. So we have a situation where any number of genes can be implicated but there is still more research to be done . The human genome is a very big, complex thing. ...Read more
Is it yet known what genes make one likely to get asthma? Are some of the genetic mutations known and can be tested for?
Phenotypes of Asthma: There are particular chromosomes noted for being associated with the asthma genotype but this does not mean they are a part of the asthma phenotype (genes displaying the disease). There is no testing except for symptoms and pulmonary function testing (including direct and indirect provocation testing) to determine asthma. ...Read moreSee 1 more doctor answer
Can u have atypical cystic fibrosis if u have asthma, severe pancreas involvement & CFTR m470v? Report indicates a 2nd gene may be rare or unknown
Maybe: Surprisingly, M470V is a common variation. Studies have shown 50% of the population has this mutation and actually less likely to cause CF. Most individuals with CF and carry M470V have some other hidden etiology that is the cause, rather than M470V. Genetic expression may be variable and so will be the clinical manifestations. Speak with your doc and a geneticist for specific information. ...Read more
Yes: Depending on which study is read, if one parent has asthma, there is a 25-40% chance that the children will have some form of it; if both parents have asthma, then there is a 60-80% chance that the children will have it. This suggests that there is a very strong genetic component to asthma but it is not the only factor. ...Read moreSee 1 more doctor answer
Sometimes: Allergic asthma is considered an inheritable condition -- meaning it can be genetic. But not all children of a mother or father with asthma will develop asthma themselves. There is a great deal of research ongoing to determine the influence of genetics vs. The environment on the development of asthma. ...Read moreSee 2 more doctor answers
Difficult to answer: Most asthma that starts in childhood can be linked to allergies. As we mature, other "triggers" may come into play such as occupational triggers (dust from manufacturing or fumes), pollution, etc. Though it sometimes can be difficult to put a finger on the cause, the treatments are usually the same- rescue inhalers and controllers (if necessary). Getting tested is always the best thing to do. ...Read more
Reliever/Preventer: This is a big topic. Most people only get symptoms every now and again (e.g. when they get a cold or exposed to dust) and their asthma will respond to a reliever like salbutamol (ventolin). Others get regular symptoms that require a preventer (there are various inhalers but most contain a low dose steroid). Have a look at this http://www.asthma.org.nz/resources/ ...Read moreSee 4 more doctor answers
Many causes 4 asthma: Asthma is a chronic inflammatory disease of the airways caused by both inherited and environmental factors. It doesn't spread like infections but develops in patients when inflammation leads to spasm of muscles around the windpipe and the airways become hypersensitive. Many factors trigger asthma, including allergies, respiratory infections, weather changes, irritants, exercise, and acid reflux. ...Read moreSee 1 more doctor answer
No: Asthma can't be cured, but its symptoms can be controlled.Prevention and long-term control are key in stopping asthma attacks before they start. Treatment usually involves learning to recognize your triggers and taking steps to avoid them, and tracking your breathing to make sure your daily asthma medications are keeping symptoms under control. In case of an asthma flare-up, you may need to use a. ...Read more
You don't: Asthma is a chronic condition of increased small airway reactions. There are genetic and environmental factors that persist throughout life, usually becoming evident in childhood. One learns to live with their asthma & present medications offer a near normal existence to most. There is no cure, there are programs that promote stability & reduced flare ups through early recognition of problems. ...Read moreSee 1 more doctor answer
Fight genetics!: That's right. 50% of asthma risk you get from your parents. If you choose ones with allergies or asthma you are already at high risk. Tell your parents not to smoke, especially when mom is pregnant with you. Tell them to get a dog and a cat before your birth. That helps. Don't live near roads with heavy diesel traffic. Avoid wood smoke & damp homes. Get exercise, sunshine & eat lots of fish. ...Read moreSee 1 more doctor answer
get to the root: The first thing is to be tested for your asthma. It is a simple test called spirometry. This , and your history, will permit the physician to make a proper diagnosis and recommend treatment. If you know now what things trigger an attack, either get rid of them (rugs, etc) or try to avoid contact (cats and dogs). Remember, get tested first. Good luck. ...Read more
Find out what: your "triggers" are...allergies/stress/environmental issues and find a good PULMONOLOGIST or ALLERGIST to help you design a medication program best for you! (Rescue inhalers, ongoing medications etc etc Some skin testing may be necessary! Start with your Primary Care Physician for a Referral Hope this helps! Dr Z ...Read moreSee 2 more doctor answers
see answer: Stop smoking and avoid second hand smoke, if you are overweight, than weight loss with a good exercise program and diet is recommended. Avoid triggers that may exacerbate your symptoms. Some people with asthma may have a genetic component and will simply need inhalers and meds to help with the disease. Best wishes. ...Read more
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