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Doctor insights on: Gemzar Treatment Pancreatic

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How effective is gemcitabine (Gemzar) for treating lung cancer?

How effective is gemcitabine (Gemzar) for treating lung cancer?

Mildly: Gemzar (gemcitabine), (gemcitabine) a form of chemotherapy can be used in non resectable lung cancer. It usually follows a couse of standard chemo such as Platinum/Taxol. When used in pancreatic Ca it is given with Abraxane, a form of Taxol which enhances Gemzar (gemcitabine) by a few weeks. After tumors respond to chemo which affects the tumor DNA, stem cells resistant to chemo reappear. Better results are now seen with anti PD-1. ...Read more

Dr. Louis Gallia
3 doctors shared insights

Pancreas (Definition)

Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more


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Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more

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Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Same drugs as other: Same chemotherapy drugs are used for treating both types of colon cancer. The only difference is lack of benefit from EGFR inhibitors(Cetuximab and Panitumumab). Avastin (bevacizumab) also works in both types. I trust that you know there are 3 chemo drugs that are widely used(5FU or Capecitabine, Irinotecan and Oxaliplatin) ...Read more

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What is prognosis With chemotherapy for metastic colon Cancer ?

What is prognosis With chemotherapy for metastic colon
Cancer ?

So many variables: Too many variables to give you a pertinent answer. Consult your oncologist to help you with clinical decisions ...Read more

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How effective is the FOLFIRI chemotherapy regimen for treating colon cancer?

How effective is the FOLFIRI chemotherapy regimen for treating colon cancer?

Some effect: Single drug chemotherapy has failed to produce significant improvement in colorectal Ca. Combination chemo as in FOLFIRI with irinotecan has added about 5 month prolongation in survival and with immunotherapy using Avastin (bevacizumab) or Erbitux an additional 2-3 months can be observed. Chemo-Immuno with a mAb targeting the immunogenic protein appears to be giving further enhancement. ...Read more

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Treatment for retroperitoneal scarcomas?

Treatment for retroperitoneal scarcomas?

Consult doctor: You need to consult a good oncologist for the answer to that question. ...Read more

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Treatment for hepatoblastoma?

Treatment for hepatoblastoma?

Surgery: Hepatoblastoma is the most common liver cancer in children. Treatment requires a biopsy to make a diagnosis. Oftentimes the tumor is resectable, if not then chemotherapy and subsequent second look surgery if tumor responds. ...Read more

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Can radiation treatment and chemotherapy cure esophageal cancer?

Can radiation treatment and chemotherapy cure esophageal cancer?

Sometimes: The two main types of esophageal cancer are adenocarcinoma and squamous cell carcinoma. Cure with chemotherapy and radiation alone is much more likely with squamous cell carcinoma. The exact cure rate is dependent on the stage of the cancer, but cure with just chemotherapy and radiation is rare. ...Read more

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How effective is the FOLFIRI-Bevacizumab chemotherapy regimen for treating colon cancer?

How effective is the FOLFIRI-Bevacizumab chemotherapy regimen for treating colon cancer?

Moderately useful: FOLFIRI-Bev is the standard, commonly used first line chemotherapy for metastatic Colon cancer. It can add about 12 to 18 months extra to your life such that an average patient can live for 2 to 3 years(some live upto 5-6 years... depending on sites of metastases and their response to chemotherapy. You need tell us more about your history such as dates of diagnosis and treatments/results so far?? ...Read more

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How effective is the IFL-Bevacizumab chemotherapy regimen for treating colon cancer?

How effective is the IFL-Bevacizumab chemotherapy regimen for treating colon cancer?

Better than chemo: Combining bevacizumab (BV)—a recombinant, humanized mAb targeting VEGF with irinotecan, fluorouracil (FU), and leucovorin (LV; IFL) has increased survival of patients with metastatic colorectal Ca compared with IFL It appears necessary to use combination therapy in treatment and has supported the concept that the use of immunochemotherapy improves results over chemo alone. ...Read more

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How effective is the IFL chemotherapy regimen for treating colon cancer?

How effective is the IFL chemotherapy regimen for treating colon cancer?

It is an old regimen: It is one of the effective treatment regimens for metastatic colon Cancer which first appeared on the scene more than 5 years back and became popular for a while to be soon upgraded with other more effective modern regimens which also include Avastin (bevacizumab) in combination with chemotherapy. ...Read more

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What is radiation therapy treatment for colon cancer?

What is radiation therapy treatment for colon cancer?

Energy beams: For certain types of colorectal cancer, energy beams are focused in the cancerous area. These beams are designed to kill cancer cells and decrease the chance of the tumor growing back. Depending on the situation, radiation can be used either before an operation or after an operation. ...Read more

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Is herceptin (trastuzumab) effective in treating bowel cancer?

No: There is no evidence that Herceptin (trastuzumab) is useful in treating colon cancer. It' s use has been expanded to patients with metastatic esophageal and stomach cancers who over express the her2 protein ...Read more

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How effective is the XELOX chemotherapy regimen for treating colon cancer?

How effective is the XELOX chemotherapy regimen for treating colon cancer?

Relatively good: According to the Journal of Clinical Oncology XELOX is a highly effective first-line treatment for metastatic colon cancer. To be more accurate (55%) of patients achieve a response, and 30% experience disease stabilization for more than 3 months following treatment. Always consult with your oncologist. ...Read more

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Pancreatic cancer, ampullary tumor. Whipple procedure. Spread to liver, not respectable. Chemo for 6 months and continuing. Prognosis?

Pancreatic cancer, ampullary tumor. Whipple procedure.  Spread to liver, not respectable. Chemo for 6 months and continuing. Prognosis?

Poor: While Whipple is the best approach for a primary pancreatic or ampullary lesion, the recurrence rate at 1-2 yrs is 90%. Chemo either of the FOLFIERI or Genciabine /Abraxane combo have limited effects on liver mets which in pancreas are not considered amenable to resection. There is an FDA protocol using specific monoclonals targeting pancreas that might be available but only after chemo failure ...Read more

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How effective is capecitabine (Xeloda) for treating colon cancer?

How effective is capecitabine (Xeloda) for treating colon cancer?

Good: Xeloda by itself is similar to 5 FU regimen. However these days we tend to add other medications such as oxalipatin and sometimes avastin (bevacizumab) depending on the stage. ...Read more

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What chemotherapy treatments exists for patients with esophageal cancer?

What chemotherapy treatments exists for patients with esophageal cancer?

Many: It depends on the type of esophageal cancer and the stage. Cisplatin plus 5-fu is a common regimen, and it is sometimes given with radiation. Other types of chemo being studied include taxol, gemciteabine, irinotecan, and xeloda (capecitabine). A good website for cancer information is www.Cancer.Gov, the national cancer institute website. Good luck! ...Read more

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Which is best treatment for pancreatic cancer?

Which is best treatment for pancreatic cancer?

Depends: Several factors: 1) resectability 2) comorbidities of the patient 3) stage. So depends on the stage. If metastatic, surgery not indicated. If not metastatic, is it resectable? Hope this helps. ...Read more

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Is folfiri alone effective for metastic colon cancer than irinotecan alone ?

Is folfiri alone effective for metastic colon cancer than irinotecan alone ?

Two drugs vs one dru: Folfiri contains two drugs in the combination: 5-FY(Folinic acid) and Irinotecan. This combination is more effective than using irinotecan alone. It is often combined with Avastin (bevacizumab) in case it is being used to treat colon cancer. ...Read more

Dr. M. Hytham Beck
19 doctors shared insights

Gemcitabine Hydrochloride (Definition)

Gemcitabine hydrochloride ...Read more


Dr. Katharine Cox
21 doctors shared insights

Gemzar (Definition)

Gemzar ...Read more