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Doctor insights on: Gemcitabine Hydrochloride

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Dr. William Singer
15 doctors shared insights

Gemcitabine Hydrochloride (Overview)

Gemcitabine hydrochloride is a cancer agent.


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Can gemcitabine be substituted for taxotere (docetaxel)?

Can gemcitabine be substituted for taxotere (docetaxel)?

Gem for taxotere (docetaxel): Short answer is no. It cannot be substituted. Now depending upon the underlying cancer whether lung, breast, pancreatic or any other primary solid tumor, one can use taxol, Abraxane or Navelbine (vinorelbine) (they are taxanes like taxotere). If we want to move to a different agent altogether, then Gemzar or a no of other drugs would be available depending upon what the primary tumor is. ...Read more

Dr. William Singer
15 doctors shared insights

Gemcitabine Hydrochloride (Overview)

Gemcitabine hydrochloride is a cancer agent.


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Is metformin hydrochloride (glucophage xr) nephro toxic?

Is metformin hydrochloride (glucophage xr) nephro toxic?

Not exactly: If you have a moderate degree of renal disease, metformin can cause lactic acidosis, which is very serious. If you do not have renal disease, metformin is quite safe. ...Read more

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How do I tell my daughter about a side effect of gemcitabine chemo?

How do I tell my daughter about a side effect of gemcitabine chemo?

Gemcitabine: Side effects of gemcitabine include: leukopenia, neutropenia, thrombocytopenia, bleeding, nausea/vomiting, diarrhea, infection, dyspnea, pneumonitis, pulmonary fibrosis, ards, hepatic failure, mi, renal failure, hemolytic-uremic syndrome, array is, vasculitis, skin runs, pain fever, alopecia, paresthesia, flu syndrome, stomatitis, somnolence, and others. ...Read more

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What is the nature of gemcitabine/carboplatin side effects?

What is the nature of gemcitabine/carboplatin side effects?

See below: This combination of chemotherapy can lead to fatigue, nausea and vomiting, low blood counts, neuropathy. It is most commonly administered for lung cancer, but also can be used in other cancers. ...Read more

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What side effects are associated with Gemzar (gemcitabine)?

Gemzar (gemcitabine): See: http://www.drugs.com/sfx/gemcitabine-side-effects.html

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What is Gemzar (gemcitabine)?

Gemzar (gemcitabine): "Gemzar is used to treat cancers of the pancreas, lung, ovary, and breast. See: http://www.drugs.com/gemzar.html ...Read more

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Who should not take Gemzar (gemcitabine)?

Gemzar (gemcitabine): "Gemcitabine is contraindicated in those patients with a known hypersensitivity to the drug." See: http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a625c92b-c569-4b98-8d2e-2b3f5e12b34f ...Read more

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Does the chemo drug gemzar (gemcitabine) raise blood sugar in a diabetic?

Not known as such: Anything is possible, but this is not a common known side effect of gemzar/gemcitabine which has many side effects. You are taking this med, likely that you are on something else as well which may be the cause. Also, when ill, sugar levels tend to rise as well. Best is to consult your doc... Good luck. ...Read more

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What is the difference between gemzar (gemcitabine) & taxol? I have three stage 4 cancers.

What is the difference between gemzar (gemcitabine) & taxol?  I have three stage 4 cancers.

Side effects vary: Gemzar (gemcitabine) is generally well tolerated given weekly 2 out of 3 or 3 out of 4 weeks per cycle. Usually does not cause hair loss or neuropathy. Taxol can be given weekly or every 3 weeks and with risk of reactions during infusion (steroid premedication needed), some hair loss and significant neuropathy. ...Read more

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How effective is gemcitabine (Gemzar) for treating lung cancer?

How effective is gemcitabine (Gemzar) for treating lung cancer?

Mildly: Gemzar (gemcitabine), (gemcitabine) a form of chemotherapy can be used in non resectable lung cancer. It usually follows a couse of standard chemo such as Platinum/Taxol. When used in pancreatic Ca it is given with Abraxane, a form of Taxol which enhances Gemzar (gemcitabine) by a few weeks. After tumors respond to chemo which affects the tumor DNA, stem cells resistant to chemo reappear. Better results are now seen with anti PD-1. ...Read more

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Do you know if there are less toxic chemotherapeutic agents than gemzar (gemcitabine) and carboplatin for treating bladder cancer?

Do you know if there are less toxic chemotherapeutic agents than gemzar (gemcitabine) and carboplatin for treating bladder cancer?

Bladder cancer: You need to speak to the oncologist (P) involved with the care of the patient. There are 4 different types of bladder cancer and the treatment the patient is currently on may be the best and/or only choice. Speak to the O caring for the patient for information as to why the O chose those drugs, as the O knows the patient the best and can give you a meaningful response. Good luck. ...Read more

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In general, is Gemzar (gemcitabine) as chemo for pancreatic cancer more potent with many more side effects that most other agents, like 5-FU?

In general, is Gemzar (gemcitabine) as chemo for pancreatic cancer more potent with many more side effects that most other agents, like 5-FU?

One of the best drug: Gemzar (gemcitabine) was the first approved drug and was superior to 5-FU for treating this cancer . So it continues to be the key drugs in the newer combinatiions being developed(or recently developed such as NAb-Paclitaxel+Gemzar (gemcitabine)). It does not have any serious toxicities just lowers the blood counts which is mostly inconsequential. ...Read more

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What is the success rate of a patient taking gemzar (gemcitabine) for metastatic breast cancer?

What is the success rate of a patient taking gemzar (gemcitabine) for metastatic breast cancer?

It depends: The success of gemcitabine (or other chemotherapy) depends on several factors. Where the cancer is, what prior treatments have been administered, and if anything in addition to gemcitabine is being administered. Gemcitabine is effective in about 1/3 of patients treated if it is the first drug administered for metastatic breast cancer. These chances decline if it is the 2nd, 3rd or later treatment. ...Read more

Dr. Sanjiv Kaul
17 doctors shared insights

Gemzar (Definition)

Gemzar ...Read more