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Doctor insights on: Gemcitabine

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Can I take anitacids while taken gemcitabine? Thanks in advance.

Can I take anitacids while taken gemcitabine? Thanks in advance.

Very much so: Gemcitabine is a chemotherapeutic agent that kills cancer cells undergoing DNA synthesis. It appears to act through inhibition of DNA polymerase. It is given by intravenous infusion, over a period of 30 minutes. Possible Side Effects include effect on WBC and on the GI tract for which one takes anti-nausea medications including antacids, (e.g. milk of magnesia, (magnesium hydroxide) calcium tablets such as Tums), sal ...Read more

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What is Gemzar (gemcitabine)?

What is Gemzar (gemcitabine)?

Gemzar (gemcitabine): "Gemzar is used to treat cancers of the pancreas, lung, ovary, and breast. See: http://www.drugs.com/gemzar.html ...Read more

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Who should not take Gemzar (gemcitabine)?

Gemzar (gemcitabine): "Gemcitabine is contraindicated in those patients with a known hypersensitivity to the drug." See: http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a625c92b-c569-4b98-8d2e-2b3f5e12b34f ...Read more

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Can gemcitabine be substituted for taxotere (docetaxel)?

Can gemcitabine be substituted for taxotere (docetaxel)?

Gem for taxotere (docetaxel): Short answer is no. It cannot be substituted. Now depending upon the underlying cancer whether lung, breast, pancreatic or any other primary solid tumor, one can use taxol, Abraxane or Navelbine (vinorelbine) (they are taxanes like taxotere). If we want to move to a different agent altogether, then Gemzar or a no of other drugs would be available depending upon what the primary tumor is. ...Read more

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What side effects are associated with Gemzar (gemcitabine)?

Gemzar (gemcitabine): See: http://www.drugs.com/sfx/gemcitabine-side-effects.html

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What is the nature of gemcitabine/carboplatin side effects?

What is the nature of gemcitabine/carboplatin side effects?

See below: This combination of chemotherapy can lead to fatigue, nausea and vomiting, low blood counts, neuropathy. It is most commonly administered for lung cancer, but also can be used in other cancers. ...Read more

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How do I tell my daughter about a side effect of gemcitabine chemo?

How do I tell my daughter about a side effect of gemcitabine chemo?

Gemcitabine: Side effects of gemcitabine include: leukopenia, neutropenia, thrombocytopenia, bleeding, nausea/vomiting, diarrhea, infection, dyspnea, pneumonitis, pulmonary fibrosis, ards, hepatic failure, mi, renal failure, hemolytic-uremic syndrome, array is, vasculitis, skin runs, pain fever, alopecia, paresthesia, flu syndrome, stomatitis, somnolence, and others. ...Read more

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Diagnosed with stage 4 pan can. Treated w/Gemcitabine/abraxane combo. Pretreatment ca19-9 was 486. Now ca19-9 is in normal range. What does this mean?

Diagnosed with stage 4 pan can. Treated w/Gemcitabine/abraxane combo. Pretreatment ca19-9 was 486. Now ca19-9 is in normal range.  What does this mean?

Temporary control: Stage 4 pancreas cancer only be managed with chemo, that is Folfieri (FOLFOX+ Irinotecan). Following this Gemzar (gemcitabine) + Abraxane gives best control as noted by normal Ca19.9 used for monitoring Follow up with serum markers and PET/CAT essential since increase in Ca19.9 suggests need for experimental trial with immunotherapy. ...Read more

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Does the chemo drug gemzar (gemcitabine) raise blood sugar in a diabetic?

Not known as such: Anything is possible, but this is not a common known side effect of gemzar/gemcitabine which has many side effects. You are taking this med, likely that you are on something else as well which may be the cause. Also, when ill, sugar levels tend to rise as well. Best is to consult your doc... Good luck. ...Read more

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What is the difference between gemzar (gemcitabine) & taxol? I have three stage 4 cancers.

What is the difference between gemzar (gemcitabine) & taxol?  I have three stage 4 cancers.

Side effects vary: Gemzar (gemcitabine) is generally well tolerated given weekly 2 out of 3 or 3 out of 4 weeks per cycle. Usually does not cause hair loss or neuropathy. Taxol can be given weekly or every 3 weeks and with risk of reactions during infusion (steroid premedication needed), some hair loss and significant neuropathy. ...Read more

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In addition to gemcitabine, are there any new treatments for advanced pancreatic cancer (in older people)?

In addition to gemcitabine, are there any new treatments for advanced pancreatic cancer (in older people)?

Cyberknife: Aggressive local treatment in addition to chemotherapy has offered good palliation of the symptoms and improvement of local control. Use of cyberknife radiosurgery in elderly with advanced pancreatic cancer patients is usually very well tolerated and improves local control and can offer palliation if patient is symptomatic. Gemzar (gemcitabine) alone or in combination with 5-fu mainstay of systemic therapy. ...Read more

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How effective is gemcitabine (Gemzar) for treating lung cancer?

How effective is gemcitabine (Gemzar) for treating lung cancer?

Mildly: Gemzar (gemcitabine), (gemcitabine) a form of chemotherapy can be used in non resectable lung cancer. It usually follows a couse of standard chemo such as Platinum/Taxol. When used in pancreatic Ca it is given with Abraxane, a form of Taxol which enhances Gemzar (gemcitabine) by a few weeks. After tumors respond to chemo which affects the tumor DNA, stem cells resistant to chemo reappear. Better results are now seen with anti PD-1. ...Read more

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What are typical side effects of liver cancer chemo therapy consisting of Gemcitabine + Oxaliplatin ( GEMOX) ?

What are typical side effects of liver cancer chemo therapy consisting of Gemcitabine + Oxaliplatin ( GEMOX) ?

Modest side effects: Gemcitabine is a well tolerated chemo drug. It can cause some decrease in blood counts, so monitor your CBC periodically(something your oncologist will discuss and do it for you). Oxaliplatin has some additional side Effects like nausea and neuropathy, yet these are manageable by any good oncologist. So I would advice you to proceed with chemo and wait to worry if you have any side effects. ...Read more