Top
20
Doctor insights on: Gastrointestinal Stromal Tumor Prognosis

Share
1

1
Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? carcinoid Neuroendocrine tumors?

Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? carcinoid Neuroendocrine tumors?

Complicated question: Carcinoids are carcinomas, usually more slow growing than adenocarcinomas. For information in this topic you may consult this link: http://www.webmd.com/cancer/carcinoid-tumors#1 ...Read more

Neoplasms (Definition)

"tumor" literally translates as "mass", so even a fresh bruise could be called a "tumor". Doctors use the term "neoplasm" (tranlates literally as new growth) to describe tumors that are abnormal growths of cells. These may be benign or malignant; "malignant" = cancer. In everyday usage, we use "tumor" ...Read more


2

2
Metastatic carcinoma omental tissue with unknown source men?

Metastatic carcinoma omental tissue with unknown source men?

Unfortunate: This is usually an unfortunate situation. The most common primary site will be somewhere in the intestinal tract, like the stomach. The pathologists will try many stains on the tissue to help define the origin. This helps with choosing the most appropriate chemotherapy. ...Read more

See 1 more doctor answer
4

4
Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more

5

5
What is mucin-producing metastatic colonic adenocarcinoma?

Subtype of colon Ca: Mucin producing metastatic adenoca of the colon is derived from a primary adenoCa of colon producing large amounts of extracelluar mucin with greater than a 50% mucinous component.. The proximal colon and appendix represents 10-20% of these colorectal neoplasms . The rt. colon is the usual source for most of these lesions presenting with more advanced forms of disease than other colonic sites. ...Read more

6

6
What is anaplastic bladder tumor.?

What is anaplastic bladder tumor.?

Small cell type.: This is a rare form of bladder cancer which tends to spread to other parts of the body. This is composed of small/oat cells, and has a poor prognosis. ...Read more

7

7
Bladder tumor pathology showed low grade, noninvasive tumor. What will treatment be? Chemo, etc?

Bladder tumor pathology showed low grade, noninvasive tumor. What will treatment be? Chemo, etc?

Intravesicle meds: The treeatment of bladder cancer is based entirely on the extent of the mucosal invasion of muscle of the bladder. When the latter occurs surgery is required along with possible RT. When superficial it is managed by intra bladder chemo or BCG. ...Read more

See 1 more doctor answer
8

8
Urothelial carcinoma of the bladder with transmural and direct prostatic stromal invasion: does extent of stromal invasion significantly impact patient outcome?

Urothelial carcinoma of the bladder with transmural and direct prostatic stromal invasion: does extent of stromal invasion significantly impact patient outcome?

Yes and No: Survival by stage which correlates with invasiveness shows survival drop as stage increases. However, the staging system is going to calll 1mm into the prostate a t4a and 25mm into the prostate as the same. So, it is hard to tell that the exactly invasion depth into the prostate is proven to correlate with outcome. In general...The more aggressive it is, the worse patients do. ...Read more

9

9
Colon biopsy:huge tubulovillous adenoma with marked atypia, multi foci adenocarcinoma in situ &one tiny focus suggestive of micro invasion.Is it cancer?

Colon biopsy:huge tubulovillous adenoma with marked atypia, multi foci adenocarcinoma in situ &one tiny focus suggestive of micro invasion.Is it cancer?

Yes: Adenocarcinoma in situ is cancer. The area suggestive of micro invasion suggests you should have rather aggressive followup screening which I am sure your doctor has, or will soon suggest. Stay on top of this and follow his/her advice. ...Read more

See 1 more doctor answer
10

10
Colon surgery:tumor size=2cm.Pathologic staging(pt3, n1b, mx).2/17 lymph nodes show metastatic.Margins of resection free of carcinoma.Need chemotherapy?

Colon surgery:tumor size=2cm.Pathologic staging(pt3, n1b, mx).2/17 lymph nodes show metastatic.Margins of resection free of carcinoma.Need chemotherapy?

Yes: Chemotherapy regimens based on the drug Fluorouracil (5-fu) have been part of the treatment for high-risk stage ii or stage iii colon cancer. Many clinical trials have shown that these regimens improve overall survival primarily by reducing the high risk of recurrence within the first two years after surgery. ...Read more

11

11
Mesothelioma biopsy says 'portions of fibrous tissue infiltrated by malignant cells forming nests. tumor cells +'ve for CK7 and calretinin. prognosis?

Mesothelioma biopsy says 'portions of fibrous tissue infiltrated by malignant cells forming nests. tumor cells +'ve for CK7 and calretinin. prognosis?

Marker not prognosis: CK7 and calretinin are used to verify that the tumor is mesothelial in origin (versus adenocarcinoma of the lung). It does not provide information about prognosis. Factors associated with pleural mesothelioma prognosis include: functional status, blood counts, histology (epithelial best vs fibrosarcomatous poorest), and tumor size (degree of involvement of pleural cavity). Several new trials. ...Read more

13

13
Is renal cell carcinoma stage 4 an aggressive cancer?

Is renal cell carcinoma stage 4 an aggressive cancer?

Stage 4 : Stage 4 renal cell carcinoma usually means that the cancer has spread to other parts of the body. At this stage, the cancer is consider very aggressive. www.peedoc.com @drhtay. ...Read more

14

14
Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, Ive used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more

16

16
What about neuroendocrine (islet cell tumors)?

What about neuroendocrine (islet cell tumors)?

Interesting tumor: Overally, neuroendocrine tumors are often capable of over-producing hormones that your body naturally makes. Islet cells are cells that are naturally present in the pancreas and produce a number of hormones, most notably insulin. Insulin helps you break down and digest sugars. Patients with an islet cell tumor can produce too much Insulin resulting in weight & gain and low blood sugars. ...Read more

See 1 more doctor answer
17

17
Ovarian cancer, omental caking, spread though peritoneum --what is prognosis?

Probably not great.: This seems like advanced disease that is relatively widespread. This would likely be treated with chemotherapy, like Paclitaxel and cisplatin.In cycles. This has been shown to have a 5 year survival of up to 20%. ...Read more

See 2 more doctor answers
18

18
Grade 2 invasive ductal carcinoma infiltrating as cords and tumour cells in a fibroadipose stroma, what does this mean?

Grade 2 invasive ductal carcinoma infiltrating as cords and tumour cells in a fibroadipose stroma, what does this mean?

Grade 2: There are 2 basic forms of breast cancer, ductal and lobular. Yours tumor is a ductal but it sounds like it has some lobular features, in particular it's infiltrating as cords sometimes called "Indian file infiltration". I don't think this has any clinical significance. See your oncologist and follow their advice. Most important is knowing lymph node status. Best of luck and God bless. ...Read more

See 1 more doctor answer

Prognosis (Definition)

The prognosis is the predicted outcome or "forecast" for a disease or process. It is only an estimate but is likely based on past experience or data taking into account the individual's overall health status. It may suggest progression of disease ...Read more


Dr. Qamar Khan
1 doctor shared a insight

Gastrointestinal (Definition)

Definition: anything pertaining to ...Read more