Doctor insights on:
Gastrointestinal Stromal Tumor Prognosis
Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? carcinoid Neuroendocrine tumors?
"tumor" literally translates as "mass", so even a fresh bruise could be called a "tumor". Doctors use the term "neoplasm" (tranlates literally as new growth) to describe tumors that are abnormal growths of cells. These may be benign or malignant; "malignant" = cancer. In everyday usage, we use "tumor" ...Read more
Unfortunate: This is usually an unfortunate situation. The most common primary site will be somewhere in the intestinal tract, like the stomach. The pathologists will try many stains on the tissue to help define the origin. This helps with choosing the most appropriate chemotherapy. ...Read moreSee 1 more doctor answer
What does each word/phrase mean?Infiltrating, well differentiated adenocarcinoma; carcinoma focally invades superficial submucosa;no lymphovascular invasion?Is surgery advised for this type of report?
Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?
Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more
Subtype of colon Ca: Mucin producing metastatic adenoca of the colon is derived from a primary adenoCa of colon producing large amounts of extracelluar mucin with greater than a 50% mucinous component.. The proximal colon and appendix represents 10-20% of these colorectal neoplasms . The rt. colon is the usual source for most of these lesions presenting with more advanced forms of disease than other colonic sites. ...Read more
Intravesicle meds: The treeatment of bladder cancer is based entirely on the extent of the mucosal invasion of muscle of the bladder. When the latter occurs surgery is required along with possible RT. When superficial it is managed by intra bladder chemo or BCG. ...Read moreSee 1 more doctor answer
Urothelial carcinoma of the bladder with transmural and direct prostatic stromal invasion: does extent of stromal invasion significantly impact patient outcome?
Yes and No: Survival by stage which correlates with invasiveness shows survival drop as stage increases. However, the staging system is going to calll 1mm into the prostate a t4a and 25mm into the prostate as the same. So, it is hard to tell that the exactly invasion depth into the prostate is proven to correlate with outcome. In general...The more aggressive it is, the worse patients do. ...Read more
Colon biopsy:huge tubulovillous adenoma with marked atypia, multi foci adenocarcinoma in situ &one tiny focus suggestive of micro invasion.Is it cancer?
Colon surgery:tumor size=2cm.Pathologic staging(pt3, n1b, mx).2/17 lymph nodes show metastatic.Margins of resection free of carcinoma.Need chemotherapy?
Yes: Chemotherapy regimens based on the drug Fluorouracil (5-fu) have been part of the treatment for high-risk stage ii or stage iii colon cancer. Many clinical trials have shown that these regimens improve overall survival primarily by reducing the high risk of recurrence within the first two years after surgery. ...Read more
Mesothelioma biopsy says 'portions of fibrous tissue infiltrated by malignant cells forming nests. tumor cells +'ve for CK7 and calretinin. prognosis?
Marker not prognosis: CK7 and calretinin are used to verify that the tumor is mesothelial in origin (versus adenocarcinoma of the lung). It does not provide information about prognosis. Factors associated with pleural mesothelioma prognosis include: functional status, blood counts, histology (epithelial best vs fibrosarcomatous poorest), and tumor size (degree of involvement of pleural cavity). Several new trials. ...Read more
What is life expectancy of small cell neuroendrocrine carcinoma that metastizied to the brain (35 tumors) and spinal fluid (3 tumors)?
Metastatic brain ca: Poor prognosis. 6-8 months or less especially if more than one. ...Read more
Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?
Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, Ive used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more
RT NEPRECTOMY CLEAR CELL RENAL CARCINOMA(FUHRMAN GRADE 2) CONFINED TO KIDNEY.URETER RESECTION MARGIN, SINUS & HILUM , ADRENAL FREE FROM TUMOR?
Unclear: Sorry I am unclear as to what your question is. Please clarify. ...Read more
Interesting tumor: Overally, neuroendocrine tumors are often capable of over-producing hormones that your body naturally makes. Islet cells are cells that are naturally present in the pancreas and produce a number of hormones, most notably insulin. Insulin helps you break down and digest sugars. Patients with an islet cell tumor can produce too much Insulin resulting in weight & gain and low blood sugars. ...Read moreSee 1 more doctor answer
Grade 2 invasive ductal carcinoma infiltrating as cords and tumour cells in a fibroadipose stroma, what does this mean?
Grade 2: There are 2 basic forms of breast cancer, ductal and lobular. Yours tumor is a ductal but it sounds like it has some lobular features, in particular it's infiltrating as cords sometimes called "Indian file infiltration". I don't think this has any clinical significance. See your oncologist and follow their advice. Most important is knowing lymph node status. Best of luck and God bless. ...Read moreSee 1 more doctor answer
Tuberous sclerosis have a large percentage of which of the following tumors? 1-renal cell carcenoma 2-adenoma 3-angiomyolipoma 3-oncocytoma 4-sarcoma
For colon cancer,Peritoneal Carcinoma's, roughly what percentage of those malignant tumors are cancerous.I read malignant tumors are 100% cancer.
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