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Doctor insights on: Gastric Lipase

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Dr. Donald Jacobson Dr. Jacobson
Psychiatry
36 years in practice
Vanderbilt University School of Medicine
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I have gerd, 4 small gastric ulcers, & gastritis. Lipase enzymes mildly over limit, amylase levels are fine. What could this be from?

I have gerd, 4 small gastric ulcers, & gastritis. Lipase enzymes mildly over limit, amylase levels are fine. What could this be from?

Excessive acid: There could be a medical condition causing too much acidity (zollinger-ellison) syndrome, or it could be from an h. Pylorii infection. Please discuss further with your GI doc since further testing is available to figure this out. Best wishes. ...Read more

Dr. Todd Igel
354 doctors shared insights

Lipase (Definition)

Lipases, such as lipoprotein lipase and endothelial lipase, are enzymes that breakdown circulating triglycerides (tg). Specifically, lipases degrade tg rich lipoproteins including chylomicrons, very low density lipoprotein (vldl) and remnant particles produced by breakdown of chylomicron and vldl particles. Decreased lipase function leads to accumulation of ...Read more


Dr. Matt Wachsman Dr. Wachsman
Internal Medicine
32 years in practice
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Had blood test amylase 64 of 90u/l normal & lipase 67 of 13-60 u/l normal range . Ultrasound normal , pancreatitis? Feel gastric after day of alcohol

Had blood test amylase 64 of 90u/l normal & lipase 67 of 13-60 u/l normal range . Ultrasound normal , pancreatitis? Feel gastric after day of alcohol

Those are close: to the normal range and not necessarily a problem. cannot say in your particular case, but generally, tests that are within 5% of the normal range are not indicative of much. Furthermore alcohol certainly causes damage to the pancreas and some drinking can cause some (small) changes in lab tests at levels below that causing serious toxicity. ...Read more

Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
3

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What causes low lipase?

What causes low lipase?

No disease: Low lipase is not a pathologic state. You did not state the actual level and the normal ranges that the lab would have reported. ...Read more

Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
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How do I reduce my lipase level?

How do I reduce my lipase level?

Why is it elevated?: An elevated lipase is usually an indication of pancreatitis and that needs to be treated by a physician and is not an issue for self diagnosis or treatment. ...Read more

Dr. Ed Friedlander Dr. Friedlander
Pathology
40 years in practice
Northwestern University Feinberg School of Medicine
5

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Substrate name for lipase enzyme?

Olive oil: At least that's what we used for assays when i was doing a lot of clinical chemistry. Today kitmakers sell you "lipase substrate" which the physician need only do quality control on. I suspect it's olive oil. ...Read more

Dr. Arthur Heller Dr. Heller
Internal Medicine - Gastroenterology
39 years in practice
Jefferson Medical College of Thomas Jefferson University
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What does an elevated lipase and amylase mean?

Can be pancreas infl: Amylase: enzyme made by pancreas and salivary glands. Elevation can be seen with pancreatitis, mumps, vomiting/bulimia sometimes with other GI (gallbladder, ulcer), gyn issues. Lipase is a somewhat more specific pancreatic enzyme. Mild elevations non specific, very high more specific marker of pancreatic inflammation. Kidney disease screws up the values. Incr. In cystic fibrosis, celiac, . ...Read more

Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
7

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What could cause slightly elevated lipase levels?

How elevated?: It would help to know the number. Gall stones and alcohol are the common causes of elevated lipase. ...Read more

Dr. Pavel Conovalciuc Dr. Conovalciuc
Family Medicine
19 years in practice
State Medical University N Testemitanu of Republic of Moldova
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Is there any way to consume lipase with orlistat?

Why?: Orlistat is a lipase blocker causing fatty diarrhea thereby leading to weight loss. Taking lipase will cause your fats to be absorbed offsetting the effect of orlistat. It makes no sense to take both together. ...Read more

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Dr. Ed Friedlander Dr. Friedlander
Pathology
40 years in practice
Northwestern University Feinberg School of Medicine
9

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My lipase levels are elevated. What can this mean?

Maybe nothing: A mild elevation of serum lipase generally means nothing whatever. Even taking an Ibuprofen tablet may raise the level. The reference range is simply what most folks have. Lipase is assayed primarily to rule out acute pancreatitis, which is not a subtle disease and in which lipase is usually several times above the top of the reference range. ...Read more

Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
10

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My lipase level came back as 20, should I be concerned?

No: Serum lipase level of 20 is normal. Why did you have the test done? All lab results need to be interpreted in the clinical context. ...Read more

Dr. Clarence Grim Dr. Grim
Internal Medicine - Endocrinology
53 years in practice
University of Missouri-Columbia School of Medicine
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Lipase levels were mildly elevated; what would cause this?

High lipase levels: 33 F from Canada notes lipase levels mildly elevated and asks what could cause this. There are many things that can cause this including pancreatitis, gall bladder stone in pancreatic duct, meds, kidney disease, So you really need to ask the Dr who ordered it to interpret it for you as your team there knows you best. You can also google this. But I recommend uptodate.com 4 best source of med info ...Read more

Dr. Silviu Pasniciuc Dr. Pasniciuc
Internal Medicine
23 years in practice
University of Medicine and Pharmacy 'Carol Davila'
12
Dr. Thomas Knecht Dr. Knecht
Internal Medicine - Endocrinology
27 years in practice
UC San Diego School of Medicine
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Lipase level of 889. How high is this considered? Concerning?

Lipase level of 889. How high is this considered? Concerning?

Pancreatitis: Hi. What did the doc who ordered the test tell you? We order tests for a reason to either try to confirm a suspicion or rule it out. In your case, it's looking for causes of your abdominal pain and bloating. Your lipase is high, and the most common reason would be pancreatitis, which certainly could be the cause of your symptoms. Pancreatitis can make you very sick. Talk with your doc. ...Read more

Dr. Ed Friedlander Dr. Friedlander
Pathology
40 years in practice
Northwestern University Feinberg School of Medicine
14

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What are normal Lipase and Amylase levels for 27 year old female?

Depends on the lab: However, there are pitfalls. The published ranges are set so that 5% of healthy people fall outside. Low values in a person who feels and appears well aren't helpful. Just the irritation of an ERCP can raise the numbers. And 1% of humankind have an antibody that causes a high amylase without there being anything else wrong. Most mild variations from normal can be ignored. ...Read more

Dr. Kathy Robinson Dr. Robinson
Family Medicine
28 years in practice
University of North Carolina School of Medicine
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My lipase is 61u/l when the reference range is 13-60. Is this a problem???

Probably not: If your doctor suspects that there is any problem with your pancreas then they may want to repeat it but if this was just found in routine labs then I would just ignore it. Slight levels outside of the range rarely mean that there is a problem. ...Read more

Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
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What does "amylase is more sensitive and lipase test is more specific" mean?

See below:: Amylase is elevated more often in patients with panreatitis, but elevated amylase, unless substantially high does not mean pancreatitis. When lipase is elevated the person is more likely to have pancreatitis. See this site for general explanation of these terms http://gim.Unmc.Edu/dxtests/reviewof.Htm. ...Read more

Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
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Amylase elevated -250. Lipase is normal. What causes this?? Should I be concerned?

Any symptoms?: Why were these tests ordered? There are many causes of elevated amylase and it would require in person evaluation to ascertain the cause. You may consult this site for information on this topic: https://medlineplus.gov/ency/article/003464.htm For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex. ...Read more

Dr. Andrew Seibert Dr. Seibert
Internal Medicine - Gastroenterology
31 years in practice
University of Louisville School of Medicine
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Normal eus but lipase now highest ever at 1600. Causes? No drinking or other risk factors.

Normal eus but lipase now highest ever at 1600. Causes?  No drinking or other risk factors.

Need more info: Too complex a situation to be dealt with by a text message. We need to know more information, such as what does your CT scan show, and whether your amylase and white blood count are also elevated. You might consider a second opinion on HealthTap Prime, if you have your lab and x-ray reports. Otherwise, return to your gastroenterologist for further evaluation. ...Read more

Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
19

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What is considered to be a "normal lipase level" and what can you do to naturally increase it?

Where?: Lipase is usually measured in serum and it should be less than 160. It is secreted by pancreas and is normal constituent of intestine. There is no need to try to increase your serum level of lipase. If you have pancreatic deficiency, oral supplements are available, but you should discuss that with your doctor. See this site for more info. http://www.nlm.nih.gov/medlineplus/ency/article/003465.htm. ...Read more

Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
20

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Everything has been normal and I have no symptoms. Are there other reasons for lipase elevation?

Macrolipase: In occasional cases antibody bound to lipase, macrolipase, causes increased blood levels of lipase without any ill-effects on the person. ...Read more

Gastric (Definition)

This refers to something that is ...Read more