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Doctor insights on: Gabapentin Vs Cymbalta For Fibromyalgia

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I have been diagnosed with fibromyalgia. I was taking cymbalta (duloxetine) but the cost was too high. I'm taking gabapentin 900 mg. not working any suggestions?

I have been diagnosed with fibromyalgia. I was taking cymbalta (duloxetine) but the cost was too high. I'm taking gabapentin  900 mg. not working  any suggestions?

Cymbalta (duloxetine): Is an antidepressant, which recently has been launched as a generic with lower costs to the public. You may like to try again. Gabapentin, a neurotrophic anticonvulsant, can be increased up to 3600 mg/ day. Both medications are used together or separate for the treatment of fibromyalgia. Discuss with your doctor to start another antidepressant if Cymbalta (duloxetine) is not an option. ...Read more

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Gabapentin (Definition)

Also called neurontin, (gabapentin) is an anticonvulsant medication used to treat seizure, also for post-herpetic neuralgia & other neuropathic pains, as well as restless leg syndrome. It works by lowering excitation ...Read more


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I've have fibromyalgia and currently taking gabapentin. I've tried amitryptaline and cymbalta (duloxetine) but had bad reactions. What are my other options?

I've have fibromyalgia and currently taking gabapentin. I've tried amitryptaline and cymbalta (duloxetine) but had bad reactions. What are my other options?

PT, support gp, Aqua: I like a holistic approach that combines the benefits of low dose neuropathic medication like Gabapentin and possibly Tramadol for pain if necessary with some form of a mild moverment program ie Pool therapy,light aerobic exercise w/a Physical Therapist or trainer that teaches light stretching exercise, Restorative yoga or Mat PIlates. Finally I rec a support group or cognitive behavioral therapy. ...Read more

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Tried numerous meds for fibro like lyrica, cymbalta, gabapentin, savella (milnacipran). None work, not fibromyalgia?

Tried numerous meds for fibro like lyrica, cymbalta, gabapentin, savella (milnacipran). None work, not fibromyalgia?

Fibromyalgia: Certainly the diagnosis may not be correct. Make sure you have had a Rheumatology work -up. Also it may be that the meds are just not working on you. ...Read more

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I have been diagnosed w/ fibromyalgia. im currently on 60mg cymbalta, 1800mg gabapentin. is there anything i can take for pain? tylenol (acetaminophen) doesnt help.

I have been diagnosed w/ fibromyalgia. im currently on 60mg cymbalta, 1800mg gabapentin. is there anything i can take for pain? tylenol (acetaminophen) doesnt help.

Yes : Consider getting a referral if your physician is running out of safe options. Low dose naltrexone or even Ketamine are worth considering. Behavioral support to turn down the volume on pain surprisingly effective for some. Access to same is the problem. Specialized care often helpful. ...Read more

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I have fibromyalgia & am currently on cymbalta (duloxetine) & gabapentin. Is low dose naltrexone something my gp can prescribe or must a pain mgm Dr? Thx

I have fibromyalgia & am currently on cymbalta (duloxetine) & gabapentin.  Is low dose naltrexone something my gp can prescribe or must a pain mgm Dr?  Thx

Your GP will know: Since regulations on classes of drugs are subject to change from time to time and place to place, ask the GP. I'd guess that they are able to, but they might still prefer not to - that would be legitamite. So, contact your GP to ask. The benefit of a specialist might be in finding non-drug methods to optimize your outcome. Best! ...Read more

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Can I take Cymbalta (duloxetine) with gabapentin?

Interaction checker: "Using gabapentin together with DULoxetine may increase side effects such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience some impairment in thinking and judgment." See: http://www.drugs.com/interactions-check.php?drug_list=1147-0,949-2273 ...Read more

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Can I take cymbalta (duloxetine) and gabapentin together?

Cymbalta/gabapentin: I think both could be taken together-both are indicated for neuropathic pain and both are not habit forming. ...Read more

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How does cymbalta (duloxetine) work differently from gabapentin for CIPN?

How does cymbalta (duloxetine) work differently from gabapentin for CIPN?

Different mechanism: Chemotherapy-induced peripheral neuropathy (CIPN) are often treated with neuropathic medicine (e.g. Gabapentin) or selective serotonin and norepinephrine reuptake inhibitor (Cymbalta/Duloxetine). Gabapentin works by mimic GABA receptors (mainly inhibitory receptors) in the synaptic pathway, reduce excitation of neurons. Duloxetine is believe to inhibit pro-inflammatory cytokines in the brain. ...Read more

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Does cymbalta (duloxetine) work better then gabapentin for nerve pain ?

Does cymbalta (duloxetine) work better then gabapentin for nerve pain ?

Cymbalta (duloxetine): Both medications are good but they are different. Cymbalta (duloxetine) works on 2different sites than gabapentin. Both are recommended in chronic pain. If you have not had success with gabapentin this maybe an option. ...Read more

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What drug has the least side effects to treat pain...Gabapentin lyrica (pregabalin) or cymbalta?

Would pich gabapenti: Any day i would pick Gabapentin over other based on clinical experience with side effects unless Gabapentin is not working well for patient. ...Read more

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If I had an adverse reaction to gabapentin for pain am I likely to suffer the same fate with cymbalta (duloxetine)? I know they work differently but still worried

If I had an adverse reaction to gabapentin for pain am I likely to suffer the same fate with cymbalta (duloxetine)? I know they work differently but still worried

Not necessarily: Cymbalta (duloxetine) and gabapentin are different classes of medications with different side effects. However, good to tell prescribing doctor about medications you did not tolerate and why. Some people are more sensitive in general to meds. Keep track of your responses. Discuss your concern with prescribing doctor. Ask what side effects might occur and what to do in that event. Take care. ...Read more

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What meds should I try to eliminate, gabapentin, cymbalta, (duloxetine) welbutrin, or remeron?

Ask your doctor: For some individuals using a combinations of medications allows them to maximize therapeutic benefit with minimizing dose dependent side effects . But for most of us "less is more". While it may be advisable to simplify your meds the specific choice and how to change the regimen requires a shared decision plan between you and your doctor. ...Read more

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What other drugs are available for nerve pain if Gabapentin, Lyrica (pregabalin) and Cymbalta don't work ?

What other drugs are available for nerve pain if Gabapentin, Lyrica (pregabalin) and Cymbalta don't work ?

Think beyond drugs: Medications are one way of controlling nerve pain. Pain is a complex holistic process. You may be able to decrease need for meds by addressing other issues. That includes nutrient status, stress or emotional trauma that may have accompanied or pre-dated the injury, and movement and use of the limb. It's a complex topic. You might look for a doc who does integrative or functional medicine. ...Read more

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Husband taking gabapentin and cymbalta (duloxetine) for neuropathy. Now can't have an ejaculation, close to it. Should he seek another opinion or check prostrate?

Husband taking gabapentin and cymbalta (duloxetine) for neuropathy. Now can't have an ejaculation, close to it. Should he seek another opinion or check prostrate?

To be honest: His ejaculation issues could be related to his medications and/or his neuropathy. Be aware, it's very uncommon that prostate issues are responsible for ejaculatory problems. You could visit this issue with a urologist if you're really inclined to have a second opinion. ...Read more

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Are there any medicines like Lyrica, (pregabalin) Cymbalta, and Gabapentin that don't cause weight gain?

COMMENTS: Of the listed three, Cymbalta causes nausea in 40%, and is the least likely to cause weight gain. Savella (milnacipran) may be of value in pain syndromes such as fibromyalgia, and seems to also be less troublesome. A possible alternative to gabapentin could be Grailise or Horizant, and due to duration of action may be also less weight gain. The meds cause appetite change, so less caloric intake can prevent. ...Read more

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Is it safe to take a TCA or a SSNRI for nerve pain if I had palpitations on low doses of first Cymbalta (duloxetine) (60mgOD), then gabapentin(100mgBID)?

Is it safe to take a TCA or a SSNRI for nerve pain if I had palpitations on low doses of first Cymbalta (duloxetine) (60mgOD), then  gabapentin(100mgBID)?

Palpitations: although there is some electrophysiologic effect with the above medicines in the absence of a clinical trial tolerability can not be assessed. Following initial dosing to steady-state an ECG may be of value in assessing the potential for arrhythmia by observing intervals such as the QT. Discuss this with the prescribing physician ...Read more

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I take cymbalta (duloxetine) and gabapentin for small fiber n. Gained 7 lbs in the 5 weeks i've been on GABA . Is there a med that won't cause weight gain?

I take cymbalta (duloxetine) and gabapentin for small fiber n.  Gained 7 lbs in the 5 weeks i've been on GABA . Is there a med that won't cause weight gain?

Not Realy: Weight gain with either or both of these medications are pretty typical. However, i would hope you are starting to feel better and now you can get out an exercise more to loose the extra weight. Hang in there. These medications are good ones, and worth trying for 90-120 days. ...Read more

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Dr. Laurence Badgley
1,356 doctors shared insights

Fibromyalgia (Definition)

Widespread pain and tenderness on palpation of specific muscle points, associated with variety of other symptoms that include fatigue, sleep disturbances, depression, ...Read more


Dr. Eric Levin
661 doctors shared insights

Neurontin (Definition)

Neurontin is a seizure agent which is a kind of ...Read more