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Gaba Supplements That Pass The Blood Brain Barrier
A dietary supplement, also known as food supplement or nutritional supplement, is a preparation intended to supplement the diet and provide nutrients, such as vitamins, minerals, fiber, fatty acids, or amino acids, that may be missing or may not be consumed in sufficient quantities in a person's diet. Some countries define dietary supplements as foods, while ...Read more
What is the criteria based on which you decide to prescription atenolol (doesn't cross blood brain barrier) vs metropolol (crosses blood brain barrier)?
It depends: It all depends what are you trying to treat. These medications have some similar but have different reasons for prescribing. ...Read more
Since GABA is the major inhibitory transmitter, if large amounts are introduced to the brain, can it produce anxiolosis and eventually coma?
Is magnesium l-threonate the only type of mg that crosses the blood brain barrier?What type of mg would help for GABA receptor upregulation?
Not really: Other forms of magnesium get into brain but at lower levels. There is one study in rats, not humans, that shows enhancement of learning & memory with magnesium l-threonate. In the study, the rats drank the compound in water -- 604 mg/kg/day. Of course supplement companies like life extension foundation are happy to sell you preparations of this although there are no clinical studies in humans. ...Read more
Heard that perfumes contain toxic chemicals capable of remaining in the brain for decades once crossed the blood brain barrier, is this true?
I don't think so: Our world's full of causes, and an understandable fear of "chemicals" has prompted some people to demand a "perfume-free workplace." i don't want to get into any arguments here, but i think most healthtap members will tell you these fears are not evidence-based. The most inflammatory claim about neurotoxicity is a non-peer-reviewed poster. I'll add that i very much dislike artificial fragrances. ...Read more
Since GABA is the main inhibitory transmitter in the brain, if levels rise high enough could it cause anxiolosis and eventually coma?
Do I understand?: Great question. I think you are asking whether gamma-amino butyric acid can produce excitoxicity. This is a completely different function from synaptic inhibition, and it's been reported in some animal models recently especially in the immature hippocampus and conjecturally as a cause of the brain damage from repeated alcohol / sedative withdrawl. Check the scientific papers yourself. ...Read moreSee 1 more doctor answer
Studies show that olive leaf extract interacts with the hiv's enzyme and proteins from stopping the virus from replicating thus destroying the HIV !?
Not enough: That's a far cry from showing that it will be beneficial to people with HIV infection. Lots of things destroy HIV that we can't use for treatment. We already have great drugs that stop viral replication. What we need now is something that rids the body of latent infection. Neither killing the virus nor stopping its replication will do that. ...Read moreSee 1 more doctor answer
All the medicines are absorbed in blood stream through small intestine? How it reaches its destination?
No, most though: several such as suboxone are set up to be absorbed directly from the inside of the mouth. It goes against the 2nd law of thermodynamics for drugs to "run directly to a spot". They diffuse like a drop of ink in water. for more detail on this. a directed question to me, the only MD PhD pharmacologist would be good. ...Read more
Does upregulation of insulin receptors occur in neurons just as other cells in the body, if the brain is always receiving a steady supply of glucose?
In the case of a stimulant overdose. Would labetalol protect the CNS (and not just the blood vessels) from any damage if administered early enough?
Understanding that deplin is the methyl folate (folic acid) needed to cross blood brain barrier, why is the dose so high 7.5 or 15mg? Non script mf is a lot lower
Biological activity: The l-methyl folate (folic acid) is the biologically active form and will directly affect receptors. You need to know that as we age, fully 52% of adults start to lose the ability to chemically convert folate (folic acid) properly. Therefore, over the counter folate (folic acid) is not identical, and the "methyl folate (folic acid)" sold in health food stores is often the reverse optical isomer and would be fully inactive. ...Read moreSee 1 more doctor answer
What evidene exists on short-term cocaine use on the cardiovasulature, heart, brain blood supply, or the central nervous system? Is damage reversible?
Vasoconstriction: Cocaine causes blood vessels to shrink down (vasoconstrict). This increases blood pressure and decreases blood flow to vital organs. This can cause strokes, kidney failure, heart attacks, etc. The constriction is temporary, but the damage can be permanent. ...Read moreSee 1 more doctor answer
Is there any evidence that Betablockers deplete levels of CoQ10 in the body?I've heard taking CoQ10 can interfere with antiplatelet and blood thinners
Yes, possibly: While not widely known, according to http://tinyurl.com/zfr2xre beta-blockers can lower CoQ10 levels, and CoQ10 can reduce the dose of beta-blockers needed, so I advise all on beta-blockers to take CoQ10. CoQ10 may reduce effectiveness of Coumadin and Plavix, though it's not clear if that is clinically significant. If you take a steady dose of CoQ10 you can adjust the dose of Coumadin accordingly. ...Read moreSee 1 more doctor answer
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