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Aspergers: Research is suggesting spectrum kids may be awash in serotonin in utero. There is speculation that ssri's may not be the best route in treating some of the difficulties associated with the spectrum because there may already be too much serotonin. Hopefully, future research will clarify. This is my take on the spectrum. http://www.youtube.com/watch?v=xg1ngp1ngds. ...Read more
I know that GABA inhibits release of dopamine, but what does glutamate do for dopamine? Precisely what would inhibition of NMDA do to dopamine?
No: It does not block Dopamine neurotransmission. It is believed to have a stabilizing effect on neural electrical hyperactivity, this it was developed to help control seizures or epilepsy. That is how some 'mood swings' may not be, strictly speaking, 'bipolar' as a seizure disorder of mood-regulating structures of the brain, the limbic system, could give you a very similar set of symptoms. ...Read moreSee 2 more doctor answers
They don't: Benzodiazepines increase the activity and potentcy of gaba receptors, which is an inhibitory neurotransmitter. Increasing the activity of gaba decreases anxiety and is sedating to lesser or greater degrees, which is why benzodiazepines are used for insomnia, panic attacks, and anxiety. ...Read more
What happens if someone is born with with a defect in which their body doesn't produce a crucial neurotransmitter like gaba? Is there a fix for it?
Consider the basics!: To make gaba and 5-htp, 84% of the population requires l-methylfolate, p5p, ; methylcobalamin. If you get those, you actually be able to get to baseline production of dopamine, serotonin, nor-epi, and melatonin. You need those before the others....Start with the raw ingredients that your body needs. You can find out how much you are deficient by being tested for the mthfr 677 ; 1298 genotypes! ...Read more
Alcohol wd come from low GABA high glutamine, true? But glutamine supps are used sometimes?! why u give it for alc wd, doesn't it raise glut even more?
More complicated: All neurotransmitter systems are inter-connected. So, it is not just a matter of the low gaba or high glutamate (not glutamine - different chemicals), but also elevated Dopamine and adrenaline, noradrenaline, as well as changes in serotonin, acetylcholine and probably the cannabinoid system as well. What we take in our stomachs and what happens in the brain are not necessarily related. ...Read more
Could a prolactin level of 30.8 and insuf vitamin D be indicator of low dopamine needing treatment with a dopamine agonist?
Prolactin -hi, low D: The need for dopamine replacement, as in Parkinsons's , presents with motor symptoms like cogwheel rigidity,gait changes. Too much dopamine can lead to psychotic symptoms. Meds as SSRIs,gaba, estrogen opioids,risperidone can increase prolactin.May be lab variation repeat in 1 month, may be due to prolactinoma a common small mass in the pituitary, check MRI. Low Vit D is commo f/u/w/doc ...Read more
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