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Doctor insights on: Functional C1 Inhibitor Eia

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C1 Esterase Inhibitor Panel had two functional and one protein level. The protein level was 11 (20-40 ml/dL). What does that mean? Other two normal.

C1 Esterase Inhibitor Panel had two functional and one protein level. The protein level was 11 (20-40 ml/dL). What does that mean? Other two normal.

Makes no sense: C1INH assays may show low C1INH (which you appears to have) or normal C1INH level with impaired functioning if you are looking for the typical cases of hereditary edema. If the quantity is low, there cannot be normal functioning. If you do have HAE, treatment should be started promptly to prevent throat swelling. ...Read more

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If u get a steroid tendon inj & r taking a cyp450 3a4 inhibitor at the same time is it like getting 3 steroid injections?

If u get a steroid tendon inj & r taking a cyp450 3a4 inhibitor at the same time is it like getting 3 steroid injections?

No: It is still one steroid injection. Biotransformation in liver is important for drugs given trough mouth, im and IV since those effect depend on concentration of drug in blood. Liver (and p450 enzyme system) has relatively little effect on drugs injected in joints, epidural space, tendons, body cavities. ...Read more

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What can you tell me about cox-2 inhibitors?

What can you tell me about cox-2 inhibitors?

Pain med: Cox-1 (cyclooxygenase-1) is an enzyme that regulates prostaglandins, and is important for a healthy stomach lining and kidneys. Inhibition turns this off, leading to gastrointestinal bleeding. Cox-2 (cyclooxygenase-2) is an enzyme that makes the prostaglandins which increase inflammation, pain and fever. So a cox-2 inhibitor is, in effect, a pain blocker. ...Read more

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I need to know what is a reuptake inhibitor?

I need to know what is a reuptake inhibitor?

Reuptake inhibitor: Selective serotonin reuptake inhibitors (ssris) affect the concentration in the brain of the neurotransmitter serotonin, which plays a role in depression. ... Do not take an ssri if you have taken a monoamine oxidase inhibitor (maoi) in recent weeks. ... ...Read more

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Why tyramine contraindicated with mao inhibitor?

Why tyramine contraindicated with mao inhibitor?

Will cause severe BP: Tyramine in large doses can raise your blood pressure, that can cause a stroke and death. Small doses don't do that because there is enough MAO in your intestinal tract to metabolize the tyramine. When you take a MAO inhibitor, tyramine is no longer metabolized in the gut, so it is free to raise your blood pressure to a very high level. This is less likely to happen with topical MAO called emsam. ...Read more

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Why tyramine is contraindicated with mao inhibitor?

Why tyramine is contraindicated with mao inhibitor?

Increase BP: Tyramine in large doses can raise your blood pressure, that can cause a stroke and death. Small doses don't do that because there is enough MAO in your intestinal tract to metabolize the tyramine. When you take a MAO inhibitor, tyramine is no longer metabolized in the gut, so it is free to raise your blood pressure to a very high level. This is less likely to happen with topical MAO called emsam. ...Read more

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How does huperzine differ from other acetylcholinesterase inhibitors?

How does huperzine differ from other acetylcholinesterase inhibitors?

Drug out of China: Huperzine a might have some benefit similar to drugs such as donepezil, rivastigmine, or galantamine, (galantamine hydrobromide) as it too, is a cholinesterase inhibitor. Has received hype in the alternative literature, due to lack of branding and commercial ownership, but it is unlikely to be any better than the above prescription meds. Do not waste money pursuing the "chinese aricept". ...Read more

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What is an ACE inhibitor/medicine?

What is an ACE inhibitor/medicine?

Blood Pressure Treat: Ace inhibitors block the conversion angiotensin i to angiotensin ii, which constricts the vessels, increases the following: salt retention in the kidney, sympathetic tone, aldosterone and ADH (vasopressin) (anti-diuretic hormone) secretion. The inhibition of this conversion decreases blood pressure and wall stress in the heart muscle. ...Read more