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Free Kappa Lambda With K L Ratio
Kappa Lambda ratio u 1.92(L) Free kappa LT chains ur 32.10 (H) Free Lambda LT chains ur 16.70 (H) 24 hour urine What does this mean?
Test results came back and say Free Kappa Lt Chains, S 34.81 Free Lambda Lt Chains, s is 29.22Kappa,lambda ratio is 1.19. Is it myeloma What is test 4
Light chains: Light chains (kappa and lambda) are a part of the immunoglobulin molecues the body makes. A given plasma cell only makes one type of light chain, most commonly this is kappa. When immunoglobulin cells proliferate like a neoplasm, then one type will overwhelm the others. Your values are nearly even, and the ratio is not abnormal, so it is unlikely that you have myeloma or another Ig-producing lesion. ...Read more
Causes if a polyclonal gammopayhy with elevated kappa and lambda free light chains? Seems to be of the IGG type slightly elevated count.
Polyclonal IgG: It can be caused by numerous inflammatory, infectious, and malignant causes, for example; TB, Rheumatoid arthritis, cirrhosis of the liver, lymphoma, and MS. A more extensive list, click on Table 3 link inside article below. http://www.aafp.org/afp/2005/0101/p105.html http://www.ncbi.nlm.nih.gov/pmc/articles/PMC356447/ Mild elevation could simply be a mild cold with a rhinovirus. No worries. ...Read more
What is the significance of having low serum levels of kappa and lambda free light chains? I had high ch50 and normal C3 and c4.
The: Concern would be low ch50 and low c3 ; c4, like in lupus. Elevations in kappa or lambda would be of concern for myeloma, not to worry about these levels. ...Read more
Immunoglobulin free lt chains blood results : kappa free light chain 20.36 (h) lambda 12.14 normal. Kappa; dheas is 25. Crp is 2.13. Sed rate is 25.?
Labs: Cannot possibly interpret lab results in the absence of a medical history and exam. If you have had these tests ordered by a doctor, discuss results with them. ...Read more
Kappa/lambda: Hi, the normal Kappa/lambda is approximately 0.26 to 1.65. this ratio has to be interpreted along with Serum electrophoresis and also the free light chain values (kappa and lambda), if the free chain is elevated and the ratio is elevated then that could be due to plasma cell disorders like multiple Myeloma or Primary Amyloidosis if the symptoms present. Having said that it's not easy to draw ...Read more
Can you get all amyloidosis if you have kappa rather than lambda light chains? I also have a kappa lambda ratio of 175
Yes: Listen, Jane. I'm worried about you. You're already on cyclophosphamide and dexamethasone -- extremely potent medications -- yet you list no illness for which they are indicated. It's not for your thyroid cancer. You have a duty to find out exactly what is happening with you, including getting a 2nd opinion from a physician who's explain clearly. Amyloid is confusing; be proactive. ...Read more
I suspect nothing: As far as this pathologist is concerned, a sed rate of 28 is fine especially for an adult female like yourself. It's worthless unless very high, and even then only to confirm systemic inflammation. The new work on intact and fragmented antibodies shows a huge variability in the ratios of kappa and lambda and i would draw no conclusions whatever. You're a person, not numbers. How do you feel? ...Read more
My haematologist says my kappa lambda ratio is seriously skewed. Kappa light chains @580 paraproteins 30. Does this imply a poor outcome?
Bad ratio: I am surprised you do not ask your oncologist questions about your outcome. Did you not ask? If you did, did you not get a response that you understood. You oncologist (o) knows your case best of all. Give your o a call and get your answer from the physician who knows you best of all. ...Read more
I've just found out that 3 tests show low kappa/lambda ratio, with lambda light chain levels increased. Do these results mean a thing without m protein?
Check with your doc: Kappa and lambda are parts of immunoglobulins which are proteins certain white blood cells make to fight infections. These are referred to as polyclonal since they come from different cells. Some blood disorders can produce lots of m (monoclonal) kappas or lambdas that come from a single, usually malignant cell. Ask your doctor who ordered the lab test to help interpret your specific results. ...Read more
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