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Doctor insights on: Folic Acid Sickle Cell Anemia

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What is the amino acid substitution in sickle cell anemia?

What is the amino acid substitution in sickle cell anemia?

See below: The normal glutamic acid is replaced by valine at position 6 of the beta globin chain. ...Read more

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Folic Acid (Definition)

Folic acid, AKA folate (folic acid) (vit B9), is recommended for all women wanting to get pregnant -- 0.4mg (400mcg) daily, which is important for preventing birth defects like spina bifida. Women w/ a hx these disorders should take 10x that amt daily -- 4mg (4000mcg) through the 3rd month of pregnancy. It won't affect fertility, chances of conception/twins, or periods. ...Read more


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How is living with sickle cell anemia/disease?

Depends on the sever: It all depends on what kinds of sickle cell anemia you have and how severe it is. For instance someone with sickle cell trait may have no problems whatsoever. ...Read more

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Can sickle-cell anemia be detected from a test?

Can sickle-cell anemia be detected from a test?

Yes: Certain blood work - i.e. Cbc, and a hemoglobin electrophoresis, - would need to be done to establish a diagnosis of sickle cell anemia. ...Read more

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Can you develop sickle cell anemia as an adult?

Can you develop sickle cell anemia as an adult?

Yes: You may not manifest sickle cell anemia until later in life. However, you don't develop or acquire sickle cell anemia at some point in life. It is genetic so you had it since birth. ...Read more

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What can cause the symptoms of sickle cell anemia?

Anemia itself : Causes some symptoms. Sickle cells can decrease flow to organs and lead to bone pain and chest syndrome. ...Read more

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What is the long-term outlook for sickle cell anemia?

What is the long-term outlook for sickle cell anemia?

Sickle cell future: As we better understand sickle cell disease, we hope to increase the quality of life for those affected by this disease. It is essential for those who have this disease to see a physician who specializes in sickle cell. For those with very severe disease, bone marrow transplantation may offer a cure. For others, screening and healthy lifestyle choices will help manage their disease. ...Read more

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What parts of the body does sickle cell anemia effect?

What parts of the body does sickle cell anemia effect?

Several symptoms: Sickle cell anemia leads to pain in the bones. It can also lead to shortness of breath, fatigue, chest pain, strokes. It affects the bones, brain, kidneys, heart, joints, lungs and spleen. ...Read more

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Can you explain a punnet square of sickle cell anemia ?

Can you explain a punnet square of sickle cell anemia ?

In 400 words?: This sounds like homework. This is simple mendelian genetics, the old 1:2:1 ratio of outcomes if two carriers mate. So if two sickle carriers mate, 1/4 offspring will be wild-type, 2/4 will be carriers, and 1/4 will have full-blown sickle cell disease. http://www.ndsu.edu/pubweb/~mcclean/plsc431/mendel/mendel1.htm. ...Read more

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What is most commonly affected with sickle cell anemia?

What is most commonly affected with sickle cell anemia?

Several symptoms: Sickle cell anemia leads to pain in the bones. It can also lead to shortness of breath, fatigue, chest pain, strokes. ...Read more

Dr. James Ball
348 doctors shared insights

Sickle Cell Disease (Definition)

This is a genetic disorder in which hemoglobin is abnormally made., more common in people of african descent. This abnormality causes red blood cells to become stiff and fall apart. This can cause very specific symptoms: pain, pneumonias, strokes, spleen problems, and many other problems. Some have mild disease, some ...Read more


Dr. Steven Ginsberg
1,239 doctors shared insights

Anemia (Definition)

Anemia refers to any condition where there is a decrease in the red blood cells in the body. There are numerous causes of anemia but they can basically be broken down into 3 categories: decreased production of red blood cells increased destruction of red ...Read more