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Doctor insights on: Folfiri Chemotherapy

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Is cytoxan (cyclophosphamide) chemotherapy?

Is cytoxan (cyclophosphamide) chemotherapy?

Yes.: Generic name of Cytoxan is cyclophosphamide. It is a drug commonly used to treat a variety of cancers, but may also be used to treat some autoimmune disorders, such as lupus. ...Read more

Dr. Devon Webster
972 doctors shared insights

Chemotherapy (Definition)

The term chemotherapy typically is used to describe using chemicals to treat ...Read more


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What is adjuvant chemo?

What is adjuvant chemo?

Adjuvant chemo: Adjuvant chemo is chemotherapy that is given after curative surgical resection of a cancer. It is given to reduce risk of recurrence of cancer. ...Read more

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Colon cancer chemo necessary?

Colon cancer chemo necessary?

Depends on stage: Chemotherapy is never used for stage 1 cancers (early). It is sometimes used in stage 2 cancers (early but more advanced than stage 1). Chemotherapy is definitely beneficial in stage 3 cancers (locally advanced) and in stage 4 cancers (distant spread). ...Read more

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Can adriamycin (doxorubicin) (chemo) cause neuropathy?

Can adriamycin (doxorubicin) (chemo) cause neuropathy?

Yes: Doxorubicin (adriamycin (doxorubicin)) can indeed cause nerve damage, but not always the typical 'peripheral neuropathy' seen with other chemotherapy drugs. It affects the myelin sheath of nerve and ganglia and can cause 'ganglionopathy'. Symptoms include numbness/tingling in both the arms/hands and legs/feet (not just the feet). Other drugs given alongside adriamycin (doxorubicin) can add to the risk. ...Read more

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Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Get Oncotype: In order to answer this question, more details are needed (size of tumor, lymph node involvement, etc). A test that will help to decide if you need chemotherapy or not is the oncotype dx. I highly recommend you speak with your oncologist and even consider a 2nd opinion. ...Read more

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Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Same drugs as other: Same chemotherapy drugs are used for treating both types of colon cancer. The only difference is lack of benefit from EGFR inhibitors(Cetuximab and Panitumumab). Avastin (bevacizumab) also works in both types. I trust that you know there are 3 chemo drugs that are widely used(5FU or Capecitabine, Irinotecan and Oxaliplatin) ...Read more

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Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more

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Peripheral t-cell lymphoma cure: chop induction+ifosfamide/mtx + autologous transplant or romidepsim+brenduximab?

Peripheral t-cell lymphoma cure: chop induction+ifosfamide/mtx + autologous transplant or romidepsim+brenduximab?

Complex problem: Cannot comment with 2 lines of information. Need the entire clinical context. If you seek more detailed information get a formal second opinion. ...Read more

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Why etoposide administered before ifosfamide in chemotherapy ?

Why etoposide administered before ifosfamide in chemotherapy ?

NO SPECIFIC REASON: Here are 3 possible reasons: 1) Most clinical trials use this sequence, although it has been given after in other studies as well 2) Etoposide is a shorter infusion 1-2 hours, Ifosfamide typically hours to 24 hrs, requiring monitoring of urine 3) Giving etoposide 1st also allows opportunity to give IV hydration prior to ifosfamide ...Read more

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Is adjuvant therapy(chemo) effective for non-hodgkin's lymphoma cases?

Is adjuvant therapy(chemo) effective for non-hodgkin's lymphoma cases?

Yes: Chemotherapy is the primary treatment for non hodgkins lymphoma. It's effectiveness depend on several favors like stage, type of lymphoma, and the international prognostic index. ...Read more

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Chemo drugs for lung cancer ?

Chemo drugs for lung cancer
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Yes: Depending on the stage, how advanced the disease is and what type of lung cancer it is, chemotherapy can play a major role in treatment of lung cancer. ...Read more

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How is chemo drug - docetaxel (taxotere)?

How is chemo drug - docetaxel (taxotere)?

?: Sorry but your question makes no sense. What do you want to know about docetaxel? ...Read more

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How effective is the FOLFIRI chemotherapy regimen for treating colon cancer?

How effective is the FOLFIRI chemotherapy regimen for treating colon cancer?

Some effect: Single drug chemotherapy has failed to produce significant improvement in colorectal Ca. Combination chemo as in FOLFIRI with irinotecan has added about 5 month prolongation in survival and with immunotherapy using Avastin (bevacizumab) or Erbitux an additional 2-3 months can be observed. Chemo-Immuno with a mAb targeting the immunogenic protein appears to be giving further enhancement. ...Read more

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Breast cancer chemotherapy in hepatitis b patients?

Breast cancer chemotherapy in hepatitis b patients?

Challenging : Appropriate involvement of hepatologist and treatment (or prophylaxis) of hep b is imperative. ...Read more

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How effective is avastin (bevacizumab) as targeted therapy for the metastatic colorectal cancer?

See below: It is not a curall for colon cancer but is effective therapy to a large extent it depends onthe size and wehre it is. Almost certianly it requires more than this drug to get a cure if acure is possible. ...Read more

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How effective iressa (gefitinib) for lung cancer after chemo?

How effective iressa (gefitinib) for  lung cancer after chemo?

Only if ..: Gefitinib will only work if there is a egfr mutation detected on the cancer. It will not be effective if there is no egfr mutation detected. ...Read more

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What option is there if chemo fails for met colon cancer ?xeloda (capecitabine) n irinotecan failed

What option is there if chemo fails for met colon cancer ?xeloda (capecitabine) n irinotecan failed

Oxaliplatin is good: Another good chemo drug is Oxaliplatin. This is often used in combination with 5-FU and Avastin (bevacizumab). If your tumor is KRAS wild type, then EGFR inhibitors(like Cetuximab and Panitumumab) also become relevant choices to use alone or in combination with other drugs. ...Read more

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How effectice is Xeloda (capecitabine) for metastatic breast cancer?

How effectice is Xeloda (capecitabine) for metastatic breast cancer?

Quite effective: Xeloda (capecitabine) is quite an effective drug and has been used in metastatic breast cancer. The response will be higher when it is combined with other chemotherapy agent- with additional possible side effects. Discuss further with you oncologist in detail. ...Read more

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How effective is the FOLFIRI-Bevacizumab chemotherapy regimen for treating colon cancer?

How effective is the FOLFIRI-Bevacizumab chemotherapy regimen for treating colon cancer?

Moderately useful: FOLFIRI-Bev is the standard, commonly used first line chemotherapy for metastatic Colon cancer. It can add about 12 to 18 months extra to your life such that an average patient can live for 2 to 3 years(some live upto 5-6 years... depending on sites of metastases and their response to chemotherapy. You need tell us more about your history such as dates of diagnosis and treatments/results so far?? ...Read more