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Doctor insights on: Folfiri Chemotherapy

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How effective is the FOLFIRI chemotherapy regimen for treating colon cancer?

How effective is the FOLFIRI chemotherapy regimen for treating colon cancer?

Some effect: Single drug chemotherapy has failed to produce significant improvement in colorectal Ca. Combination chemo as in FOLFIRI with irinotecan has added about 5 month prolongation in survival and with immunotherapy using Avastin (bevacizumab) or Erbitux an additional 2-3 months can be observed. Chemo-Immuno with a mAb targeting the immunogenic protein appears to be giving further enhancement. ...Read more

Dr. Devon Webster
945 doctors shared insights

Chemotherapy (Definition)

The term chemotherapy typically is used to describe using chemicals to treat ...Read more


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How effective is the FOLFIRI-Bevacizumab chemotherapy regimen for treating colon cancer?

How effective is the FOLFIRI-Bevacizumab chemotherapy regimen for treating colon cancer?

Moderately useful: FOLFIRI-Bev is the standard, commonly used first line chemotherapy for metastatic Colon cancer. It can add about 12 to 18 months extra to your life such that an average patient can live for 2 to 3 years(some live upto 5-6 years... depending on sites of metastases and their response to chemotherapy. You need tell us more about your history such as dates of diagnosis and treatments/results so far?? ...Read more

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Is folfiri alone effective for metastic colon cancer than irinotecan alone ?

Is folfiri alone effective for metastic colon cancer than irinotecan alone ?

Two drugs vs one dru: Folfiri contains two drugs in the combination: 5-FY(Folinic acid) and Irinotecan. This combination is more effective than using irinotecan alone. It is often combined with Avastin (bevacizumab) in case it is being used to treat colon cancer. ...Read more

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What is chemotherapy?

Drugs for cancer: Various drugs are using alone or in combination to treat cancer. Collectively, they are called chemotherapy and can be used as single agents or in combinations. Many times biologic agents such as antibodies are also grouped in this category because the are used to fight cancer as well. ...Read more

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What is chemotherapy?

What is chemotherapy?

Chemotherapy: Is a fairly broad term to describe medications given to treat cancer. This is not necessarily limited to intravenous drugs. ...Read more

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How chemotherapy works?

Chemotherapy: Chemotherapy is a very broad term. Each agent works differently. Some replace parts of the dna of fast growing cells, some attack the way dna is repaired, some block very specific receptors needed for the cancer to grow. ...Read more

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What's chemotherapy like?

What's chemotherapy like?

Individualized: Some people tolerate chemotherapy well, and some have very severe side effects, usually weakness, nausea, vomiting, and diarrhea, and/or hair loss depending on what specific treatment you are using. The younger the better able you are to tolerate the side effects. ...Read more

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How is being on chemotherapy?

How is being on chemotherapy?

Nothing different th: Chemotherapy is use of drugs to treat cancer. Many of these drugs are quite similar to receiving other drugs like IV antibiotics. Chemotherapy does have some side effects which can be in the form of nausea or vomiting and sometimes hair loss. Blood counts tend to go down 1-2 weeks alter, so they need to be checked to make sure the white cell counts do not go down too low...This can cause infection. ...Read more