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Doctor insights on: Folfiri Chemotherapy

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How effective is the FOLFIRI chemotherapy regimen for treating colon cancer?

How effective is the FOLFIRI chemotherapy regimen for treating colon cancer?

Some effect: Single drug chemotherapy has failed to produce significant improvement in colorectal Ca. Combination chemo as in FOLFIRI with irinotecan has added about 5 month prolongation in survival and with immunotherapy using Avastin (bevacizumab) or Erbitux an additional 2-3 months can be observed. Chemo-Immuno with a mAb targeting the immunogenic protein appears to be giving further enhancement. ...Read more

Dr. Devon Webster
966 doctors shared insights

Chemotherapy (Definition)

The term chemotherapy typically is used to describe using chemicals to treat ...Read more


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How effective is the FOLFIRI-Bevacizumab chemotherapy regimen for treating colon cancer?

How effective is the FOLFIRI-Bevacizumab chemotherapy regimen for treating colon cancer?

Moderately useful: FOLFIRI-Bev is the standard, commonly used first line chemotherapy for metastatic Colon cancer. It can add about 12 to 18 months extra to your life such that an average patient can live for 2 to 3 years(some live upto 5-6 years... depending on sites of metastases and their response to chemotherapy. You need tell us more about your history such as dates of diagnosis and treatments/results so far?? ...Read more

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Is folfiri alone effective for metastic colon cancer than irinotecan alone ?

Is folfiri alone effective for metastic colon cancer than irinotecan alone ?

Two drugs vs one dru: Folfiri contains two drugs in the combination: 5-FY(Folinic acid) and Irinotecan. This combination is more effective than using irinotecan alone. It is often combined with Avastin (bevacizumab) in case it is being used to treat colon cancer. ...Read more

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What is chemotherapy?

Drugs for cancer: Various drugs are using alone or in combination to treat cancer. Collectively, they are called chemotherapy and can be used as single agents or in combinations. Many times biologic agents such as antibodies are also grouped in this category because the are used to fight cancer as well. ...Read more

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What is chemotherapy?

What is chemotherapy?

Chemotherapy: Is a fairly broad term to describe medications given to treat cancer. This is not necessarily limited to intravenous drugs. ...Read more

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How chemotherapy works?

How chemotherapy works?

Chemotherapy: Chemotherapy is a very broad term. Each agent works differently. Some replace parts of the dna of fast growing cells, some attack the way dna is repaired, some block very specific receptors needed for the cancer to grow. ...Read more

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What's chemotherapy like?

What's chemotherapy like?

Individualized: Some people tolerate chemotherapy well, and some have very severe side effects, usually weakness, nausea, vomiting, and diarrhea, and/or hair loss depending on what specific treatment you are using. The younger the better able you are to tolerate the side effects. ...Read more

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How is being on chemotherapy?

How is being on chemotherapy?

Nothing different th: Chemotherapy is use of drugs to treat cancer. Many of these drugs are quite similar to receiving other drugs like IV antibiotics. Chemotherapy does have some side effects which can be in the form of nausea or vomiting and sometimes hair loss. Blood counts tend to go down 1-2 weeks alter, so they need to be checked to make sure the white cell counts do not go down too low...This can cause infection. ...Read more

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Which products or metals is chemotherapy made of?

Which products or metals is chemotherapy made of?

Synthetic chemicals: Most chemotherapy is made from the synthetic chemicals just like any other drugs. A few of chemotherapy drugs are derived from metals like a drug called Cisplatin is derived from the metal, platinum and is widely used to treat various cancers. ...Read more

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Can chemotherapy cause a stroke?

Yes (but most don't): While cancer is a hypercoagulable state and can increase your risk for stroke, i know of one chemotherapy agent (there may be more, but it is quite uncommon) that can cause stroke. Asparaginase, used to treat certain leukemias, can cause strokes. ...Read more

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Can chemotherapy cause bursitis?

Can chemotherapy cause bursitis?

Unlikely: It's unlikely that bursitis is caused by chemotherapy. I would consider an alternative answer. Your physician can help clarify why you have bursitis, is there a variety of other issues that need to be considered. ...Read more

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What exactly is photo chemotherapy?

PUVA (Psoralen+UVA): Photochemotherapy/phototherapy generally refers to puva therapy using psoralen (taken by mouth) and then later "tanning" to ultraviolet a light (uv-a) to treat various skin conditions like atopic dermatitis, psoriasis, urticaria, cutaneous t-cell lymphoma and skin manifestations of graft-versus-host disease. The psoralen makes the offending cells in the skin sensitive to damage from ultraviolet a. ...Read more

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Will chemotherapy make you sterile?

Maybe: Chemo can definitely reduce fertility. I discuss fertility with all patients of childbearing age, and offer sperm banking to men, and referral to a fertility expert for egg harvest for women. Menstruation after chemo is generally a marker for fertility. Chemo can induce damage to the genes in sperm and eggs, and patients shouldn't conceive during chemo due to risk of birth defects. ...Read more

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Is chemotherapy actually very toxic?

Possible: Chemotherapy is a broad term for a large number of drugs used alone or in combination. Also the doses vary depending upon the disease. The are also variations in individual's susceptibility. There are also a large number of drugs used to combat side effects. I can only say that it can be anything from very toxic to mild depending on the situation. ...Read more

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Is np caused by chemotherapy curable?

Np?: Could you be more specific as to what "np" is, then we can help answer your question. ...Read more

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How expensive are chemotherapy drugs?

Varies with each dru: Many of the older drugs, widely used even now, are not too expensive. This includes nearly all of Chemotherapy drugs. The more modern drugs called targeted agents are more expensive, typically costing 6K-10K USD per rmonth. The brand new drugs in the last 5 years have started costing 10K-12K USD/month, which has created a lot of unrest in the medical community as it is no longer affordbable. ...Read more

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How can the chemotherapy affect my dad?

Good question: But impossible to answer here. Depends on what cancer he has, what chemo he gets, how healthy he is, and many other factors that we do not know. Even so, people react differently to drugs so there is always a degree of uncertainty. You need to go over this with his oncologist before he gets the chemo. ...Read more