Doctor insights on:
Depends on stage: Chemotherapy is never used for stage 1 cancers (early). It is sometimes used in stage 2 cancers (early but more advanced than stage 1). Chemotherapy is definitely beneficial in stage 3 cancers (locally advanced) and in stage 4 cancers (distant spread). ...Read moreSee 2 more doctor answers
Same drugs as other: Same chemotherapy drugs are used for treating both types of colon cancer. The only difference is lack of benefit from EGFR inhibitors(Cetuximab and Panitumumab). Avastin (bevacizumab) also works in both types. I trust that you know there are 3 chemo drugs that are widely used(5FU or Capecitabine, Irinotecan and Oxaliplatin) ...Read more
Diagnoged with cutaneous tcell lymphoma nhl.Treated with eletron beam.Interferon, gemcitabine, anthracycline, etoposide, procarbazine.Nodules over body .?
Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?
Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more
What option is there if chemo fails for met colon cancer ?xeloda (capecitabine) n irinotecan failed
Oxaliplatin is good: Another good chemo drug is Oxaliplatin. This is often used in combination with 5-FU and Avastin (bevacizumab). If your tumor is KRAS wild type, then EGFR inhibitors(like Cetuximab and Panitumumab) also become relevant choices to use alone or in combination with other drugs. ...Read more
Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?
Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more
What can prognosis b like for metastic colon cancer that chemotherapy oxyplatin and raltitrexed ?
Colon mets: Not having your chart and you in front of me makes it very hard to give you an accurate idea on prognosis. When chemo is started, that means your CA cells have gone beyond the boundaries which would have made txing it simple. The simpler the tx, the better the prgns. The harder the tx, the worse the prgns. On a positive note, f/u with your docs, stay faithful, and you might get a pleasant surprise ...Read more
Ciii ovarian cancer in 06, 1212, surgery and chemo paxitaxtel/carboplatin. In remission. Recurrence treated with tamoxifen, carboplatin alone, abraxan, then topotacan to no avail. Which chemo next?
Many options: Choosing chemo depends on many factors, so only your doctor can decide what might work for you. Drugs you haven't mentioned include altretamine, capecitabine, cytoxan, (cyclophosphamide) vinorelbine, ifosfamide, etoposide, and irinotecan. There are also several hormonal agents. And a clinical trial might be an option. Check out www.Cancer.Gov for more info. And good luck. ...Read moreSee 1 more doctor answer
Yes: Doxorubicin (adriamycin (doxorubicin)) can indeed cause nerve damage, but not always the typical 'peripheral neuropathy' seen with other chemotherapy drugs. It affects the myelin sheath of nerve and ganglia and can cause 'ganglionopathy'. Symptoms include numbness/tingling in both the arms/hands and legs/feet (not just the feet). Other drugs given alongside adriamycin (doxorubicin) can add to the risk. ...Read moreSee 1 more doctor answer
NO SPECIFIC REASON: Here are 3 possible reasons: 1) Most clinical trials use this sequence, although it has been given after in other studies as well 2) Etoposide is a shorter infusion 1-2 hours, Ifosfamide typically hours to 24 hrs, requiring monitoring of urine 3) Giving etoposide 1st also allows opportunity to give IV hydration prior to ifosfamide ...Read moreSee 1 more doctor answer
What would be best chemo / treatment after irinotecan n Xeloda (capecitabine) failed for colon cancer with mets?
Difficult to answer.: recommended chemotherapy regimens change regularly depending on the results of studies. Your oncologist should keep on top of those studies and will be able to recommend the next approved therapy or any experimental trials which may be available. I would talk further with your oncologist before making any plans. Good luck. ...Read more
Chemotherpay failed , irinotecan and oxyplatin in metastic colon cancer . Liver and peritoneal mets . Is there anything else ?
Sorry to: hear that. Discuss with your Oncologist what is the next step. Get family and spiritual support as well. Good luck ...Read more
So many variables: Too many variables to give you a pertinent answer. Consult your oncologist to help you with clinical decisions ...Read more