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Doctor insights on: Folfiri Chemo

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Is cytoxan (cyclophosphamide) chemotherapy?

Is cytoxan (cyclophosphamide) chemotherapy?

Yes.: Generic name of Cytoxan is cyclophosphamide. It is a drug commonly used to treat a variety of cancers, but may also be used to treat some autoimmune disorders, such as lupus. ...Read more

Dr. Devon Webster
977 doctors shared insights

Chemotherapy (Definition)

The term chemotherapy typically is used to describe using chemicals to treat ...Read more


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Colon cancer chemo necessary?

Colon cancer chemo necessary?

Depends on stage: Chemotherapy is never used for stage 1 cancers (early). It is sometimes used in stage 2 cancers (early but more advanced than stage 1). Chemotherapy is definitely beneficial in stage 3 cancers (locally advanced) and in stage 4 cancers (distant spread). ...Read more

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What is adjuvant chemo?

What is adjuvant chemo?

Adjuvant chemo: Adjuvant chemo is chemotherapy that is given after curative surgical resection of a cancer. It is given to reduce risk of recurrence of cancer. ...Read more

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Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Get Oncotype: In order to answer this question, more details are needed (size of tumor, lymph node involvement, etc). A test that will help to decide if you need chemotherapy or not is the oncotype dx. I highly recommend you speak with your oncologist and even consider a 2nd opinion. ...Read more

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Chemo drugs for lung cancer ?

Chemo drugs for lung cancer
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Yes: Depending on the stage, how advanced the disease is and what type of lung cancer it is, chemotherapy can play a major role in treatment of lung cancer. ...Read more

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Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Same drugs as other: Same chemotherapy drugs are used for treating both types of colon cancer. The only difference is lack of benefit from EGFR inhibitors(Cetuximab and Panitumumab). Avastin (bevacizumab) also works in both types. I trust that you know there are 3 chemo drugs that are widely used(5FU or Capecitabine, Irinotecan and Oxaliplatin) ...Read more

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Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more

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What option is there if chemo fails for met colon cancer ?xeloda (capecitabine) n irinotecan failed

What option is there if chemo fails for met colon cancer ?xeloda (capecitabine) n irinotecan failed

Oxaliplatin is good: Another good chemo drug is Oxaliplatin. This is often used in combination with 5-FU and Avastin (bevacizumab). If your tumor is KRAS wild type, then EGFR inhibitors(like Cetuximab and Panitumumab) also become relevant choices to use alone or in combination with other drugs. ...Read more

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Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more

Dr. Liawaty Ho Dr. Ho
5 doctors agreed:
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How effective iressa (gefitinib) for lung cancer after chemo?

Dr. Liawaty Ho Dr. Ho
5 doctors agreed:
How effective iressa (gefitinib) for  lung cancer after chemo?

Only if ..: Gefitinib will only work if there is a egfr mutation detected on the cancer. It will not be effective if there is no egfr mutation detected. ...Read more

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How is chemo drug - docetaxel (taxotere)?

How is chemo drug - docetaxel (taxotere)?

?: Sorry but your question makes no sense. What do you want to know about docetaxel? ...Read more

Dr. Craig Lum Dr. Lum
1 doctor agreed:
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What can prognosis b like for metastic colon cancer that chemotherapy oxyplatin and raltitrexed ?

Dr. Craig Lum Dr. Lum
1 doctor agreed:
What can prognosis b like for metastic colon cancer that chemotherapy oxyplatin and raltitrexed ?

Colon mets: Not having your chart and you in front of me makes it very hard to give you an accurate idea on prognosis. When chemo is started, that means your CA cells have gone beyond the boundaries which would have made txing it simple. The simpler the tx, the better the prgns. The harder the tx, the worse the prgns. On a positive note, f/u with your docs, stay faithful, and you might get a pleasant surprise ...Read more

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Ciii ovarian cancer in 06, 1212, surgery and chemo paxitaxtel/carboplatin. In remission. Recurrence treated with tamoxifen, carboplatin alone, abraxan, then topotacan to no avail. Which chemo next?

Ciii  ovarian cancer in 06, 1212, surgery and chemo paxitaxtel/carboplatin.  In remission. Recurrence treated with tamoxifen, carboplatin alone, abraxan, then topotacan to no avail. Which chemo next?

Many options: Choosing chemo depends on many factors, so only your doctor can decide what might work for you. Drugs you haven't mentioned include altretamine, capecitabine, cytoxan, (cyclophosphamide) vinorelbine, ifosfamide, etoposide, and irinotecan. There are also several hormonal agents. And a clinical trial might be an option. Check out www.Cancer.Gov for more info. And good luck. ...Read more

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Can adriamycin (doxorubicin) (chemo) cause neuropathy?

Can adriamycin (doxorubicin) (chemo) cause neuropathy?

Yes: Doxorubicin (adriamycin (doxorubicin)) can indeed cause nerve damage, but not always the typical 'peripheral neuropathy' seen with other chemotherapy drugs. It affects the myelin sheath of nerve and ganglia and can cause 'ganglionopathy'. Symptoms include numbness/tingling in both the arms/hands and legs/feet (not just the feet). Other drugs given alongside adriamycin (doxorubicin) can add to the risk. ...Read more

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Why etoposide administered before ifosfamide in chemotherapy ?

Why etoposide administered before ifosfamide in chemotherapy ?

NO SPECIFIC REASON: Here are 3 possible reasons: 1) Most clinical trials use this sequence, although it has been given after in other studies as well 2) Etoposide is a shorter infusion 1-2 hours, Ifosfamide typically hours to 24 hrs, requiring monitoring of urine 3) Giving etoposide 1st also allows opportunity to give IV hydration prior to ifosfamide ...Read more

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What would be best chemo / treatment after irinotecan n Xeloda (capecitabine) failed for colon cancer with mets?

Difficult to answer.: recommended chemotherapy regimens change regularly depending on the results of studies. Your oncologist should keep on top of those studies and will be able to recommend the next approved therapy or any experimental trials which may be available. I would talk further with your oncologist before making any plans. Good luck. ...Read more

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Chemotherpay failed , irinotecan and oxyplatin in metastic colon cancer . Liver and peritoneal mets . Is there anything else ?

Sorry to: hear that. Discuss with your Oncologist what is the next step. Get family and spiritual support as well. Good luck ...Read more

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Is folfiri alone effective for metastic colon cancer than irinotecan alone ?

Is folfiri alone effective for metastic colon cancer than irinotecan alone ?

Two drugs vs one dru: Folfiri contains two drugs in the combination: 5-FY(Folinic acid) and Irinotecan. This combination is more effective than using irinotecan alone. It is often combined with Avastin (bevacizumab) in case it is being used to treat colon cancer. ...Read more

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What is prognosis With chemotherapy for metastic colon Cancer ?

So many variables: Too many variables to give you a pertinent answer. Consult your oncologist to help you with clinical decisions ...Read more