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Doctor insights on: Folate Neural Tube

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How does folic acid prevent neural tube defects?

How does folic acid prevent neural tube defects?

NEURAL TUBE DEFECTS: Are one of the most common birth defects(1 in 1, 000 live births in this country). It is an opening in the spinal cord or brain that does not close properly. Folic acid and B12 help transport the necessary materials to make this happen normally. Folate (folic acid) is needed for production and maintenance of new cells, to make normal dna and rna. ...Read more

Folic Acid (Definition)

Folic acid, AKA folate (folic acid) (vit B9), is recommended for all women wanting to get pregnant -- 0.4mg (400mcg) daily, which is important for preventing birth defects like spina bifida. Women w/ a hx these disorders should take 10x that amt daily -- 4mg (4000mcg) through the 3rd month of pregnancy. It won't affect fertility, chances of conception/twins, or periods. ...Read more


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What are neural tube defects?

What are neural tube defects?

NTD: Neural tube defects are a host of lesions that affect the spinal cord. They vary in degree from spina bifida occulta ( mildest ) to craniorrachischis totalis ( severest), spina bifida, and myelomengocele being the most frequently encountered. They have been linked to a diet deficient in folate (folic acid) during pregnancy. ...Read more

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Are neural tube defect babies active?

Are neural tube defect babies active?

Possibly: It depends on multiple factors. There are different degrees of neural tube defects. Some people can have a mild defect and other may have a severe defect. It also depends on the location of the defect. Your doctor might be able to better answer this question with all of the relevant information. ...Read more

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What is neural tube defects often mentioned in pregnancy..?

Spina Bifida: "neural tube defects" is a general name for developmental problems regarding the early developing spinal cord. The most commonly known defect is called "spina bifida" -- a defect in which the developing spinal cord is open to the skin on the back of the baby. This can lead to bowel or bladder control problems, neurologic problems, and even paralysis. ...Read more

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Is there a relationship between cranioschisis and neural tube defects (ntds)?

Related conditions: Open neural tube defects affect areas from the head to end of spine. Usually referred to a Spina Bifida lower on down the vertebral column. The central nervous system needs to close early in gestation before birth. "Schisis" means open or failure to close. Carino's hiatus is a very severe condition. Consult w a pediatric neurologist is recommended ...Read more

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What are the tests for neural tube defects?

Antepartum Dx.: There are screening tests available to detect neural tube defects in the fetus. The most common is called alfa fetoprotein. The levels of this substance is significantly increased if the fetus is affected with an open neural tube defect. ...Read more

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Does prenatale vitamins contains enough folic acid to protect birth defects ?

Take vitamins: Folic acid is almost always included in prenatal vitamins because most pregnant women don't get enough of it from just what they eat. Taking folic acid for at least one month prior to conception lowers the risk of neural-tube defects, such as spina bifida, significantly. Recommended dose is 400 micrograms of folic acid every day prior to pregnancy and 600 micrograms when pregnant. ...Read more

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How can folate (folic acid) prevent birth defects?

Very important: Folate (folic acid) is used by the developing fetus in the formation of the nervous system and spinal cord. If the fetus does not receive enough folate, (folic acid) it is at risk for defects such as spina bifida, or anencephaly (no head). ...Read more

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Afp normal, enlarged brain ventricles, could it be a neural tube defect?

Neural tube defect: If AFP is normal there is likely not a neural defect, but the test is not 100% positive. ...Read more

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What is the best neural tube defect test?

NTD: The "best" test is an amniotic fluid AFP concentration. That picks up about 90% of open neural tube defects. However, an ultrasound examination also picks up the majority of open neural tube defects. ...Read more

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Afp normal, enlarged brain ventricles, is it still possible to have a neural tube defect ntd?

Afp normal, enlarged brain ventricles, is it still possible to have a neural tube defect ntd?

AFP: A normal AFP reduces the risk of an open neural tube abnormality. Enlarged cerebral ventricles are usually not associated with neural tube abnormalities. ...Read more

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Is arnold chiari malformation type one a neural tube defect?

Is arnold chiari malformation type one a neural tube defect?

No: The more accepted term is chiari malformation as arnold-chiari is an older term. This type of malformation is not a neural tube defect, but rather an abnormal migration of the cerebellar tonsils below the level of the foramen magnum (chiari type 1). This defect is attributed to a congenitally small posterior fossa, thus allowing the cerebellar tonsils to migrate downward. ...Read more

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Does folate (folic acid) deficiency anemia affect the brain and nerves?

Does folate (folic acid) deficiency anemia affect the brain and nerves?

Yes: Folate (folic acid) is needed for maintenance and repair of myelin, the covering of larger/faster nerve fibers. Deficiency in utero results in birth defects of the neural cord, low birth weight or prematurity. Deficiency will slow growth in children. Peripheral neuropathy results in adults. Deficiency is reversible if treated early enough. Nerves suffer from folate (folic acid) deficiency itself more than from anemia. ...Read more

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Will folic acid prevent Lamotrigine causing birth defects during pregnancy?

Lamictal is FDA: Pregnancy Category C. It would not be safe to assume that use of Folic Acid would be protective for potential side effects related to lamictal. ...Read more

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Has anybody heard of using vitamin b and folate (folic acid) to prevent birth defects?

Has anybody heard of using vitamin b and folate (folic acid) to prevent birth defects?

See below: Folate (folic acid) is definitely needed to prevent abnormalities of the spinal cord. Ass for vitamin b, I am unaware of any birth defects associated with low vitamin b levels. Maybe one of the obstetricians on the site will know. ...Read more

Dr. Jay Park Dr. Park
2 doctors agreed:
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Is it true that folate (folic acid) supplements prevent birth defects?

Dr. Jay Park Dr. Park
2 doctors agreed:

Yes: Folic acid deficiency in early pregnancy has been associated with neural tube defect, e.g., spina bifida. Any woman planning to get pregnant should be on vitamin supplement including folic acid. ...Read more

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Can folic acid prevent Lamotrigine causing all birth defects during pregnancy?

Can folic acid prevent Lamotrigine causing all birth defects during pregnancy?

Any drug causing: birth defects is separate from taking a supplement to support neurological development in pregnancy. Most supplements don't and aren't designed to prevent against birth defects. If you are concerned about this, discuss it with your OB/GYN doctor, and get a full evaluation of what you're taking, and what your concerns are. So, you can have piece of mind. Taking too much folic acid is not wise too. ...Read more

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Why is fetus at risk if folate (folic acid) deficiency?

Why is fetus at risk if folate (folic acid) deficiency?

Folate (folic acid): Folate is a co-factor used in cellular division. If there is a deficiency of folic acid, cells won't be able to divide properly. The net result is fewer cells. In a developing human this is associated with neural tube defects and cardiac defects. ...Read more

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Does folate (folic acid) deficiency affect brain's health of the baby ?

Does folate (folic acid) deficiency affect brain's health of the baby ?

See below: Folate (folic acid) deficiency can affect the development of the brain and spinal cord of the fetus. ...Read more

Dr. Kristi Woods
667 doctors shared insights

Folate (Definition)

Folate is a vitamin which is a kind of nutritional agent ...Read more