Doctor insights on:
Focal Segmental Glomerular Sclerosis
MRI brain results Impression- there is cerebral atrophy with subcortical WMC, consistent wit microangiopathic disease, demyelination, or giliosis?
Covering the bases: That signal that is seen in patients who age is seen very frequently. Most of the time it is what has become known as microangiopathic disease or small vessel disease. Demyelination and gliosis come with a more notable history. Gliosis or scarring and demyelination also produces symptoms that MRI is useful for. Depends on why you had the MRI in the first place. The first entity more common than 2 ...Read more
Please explain: renal cortex contains 29 glomeruli, 13 of which
are globally sclerosed. There is focal segmental mesangial
Sclerosis: So Glomeruli are Filteration units of Kidney. Since kidney's main function is Filteration; the health of glome is directly related to renal function. Sclerosis in layman term means scarring. So 13/29 glomes are scarred. Which means approximately 50% of functional units are scarred or non functional. Mesengial hypercellularity refers to the inflammation in the kidney. Very common with FSGS ...Read more
Not similar diseases: Als is very different, and is a disease of "mis-folded proteins" like alzheimers and parkinson's, and all of these affect older people. Ms is an autoimmune disease afflicting younger patients who have hereditary susceptibilities and environmental exposures. Ms can be successfully treated and controlled, but ALS does not respond well to current therapies. ...Read more
MRI showed moderate supratenatorial white matter disease suspicious of demyelinating process. Multiple nodular foci periventricular Could you explain?
Concern for MS, But: Phyllis, talk to the doctor who ordered the MRI, since he/she can interpret the MRI in the context of the symptoms that brought you to the clinic. In some cases, periventricular white matter lesions are the result of migraines, old head trauma, neuron migration issues, or MS. It is hard to know from just a description of the MRI which is the cause. Good Luck and Stay Healthy! ...Read moreSee 1 more doctor answer
F,48. Pls detail(1)"nonspec hyperintense FLAIR foci involving L.parietal+bilateral.frontal.lobes" +(2)"signal void along main intracranial vasculature?
Radiology terms: This is specialized radiology terminology and isn't helpful by itself. The radiologist should provide a conclusion at end of report as to what it all means. This must then be interpreted in context of what symptoms led to study in first place. Too much for any of us to answer in this format. Talk to the doctor who ordered the study. Good luck. ...Read more
Abnormal FDG activity involving pleural thickening in Rt lower lateral lung base compatible with inflammatory VS early neoplasticism disease. Meaning?
Pleural thickening: It means that the pleural thickening is metabolically active(i.e. It is not chronic scarring, which would be inactive). The 2 main possibilities for this, as you mention, are an active inflammation, which is benign, or neoplastic disease(tumor). Speak with your doctor. If the answer is not clear based on your entire clinical picture, biopsy could be needed to determine what it is. ...Read more
Attenuation of hep parenchyma. Diffuse capsular enhancement and focal capsular retraction on liver ct. No focal lesions. Could sle serositis cause ?
Kidney Disease: "diffuse" means all over the kidney, "parenchymal" means the solid part of the kidney that filters the liquid waste products out of the blood, and "disease" means something is wrong. Typically "diffuse parenchymal disease" means an overall medical problem with the kidney, such as diabetic nephropathy, or post-streptococcal nephritis. In the pediatric world we use this term slightly differently. ...Read more
Help me interpret vulvar biopsy. Focal squamous atypia. Ki-67 shows mild increase cell proliferation focal vin can't be excluded. Lichen sclerosis?
Nothing serious yet: This report suggests slightly abnormal changes (atypia & increased cell proliferation) which can be a reaction to irritation but there is no definitive evidence of precancerous change (VIN). In short there is nothing to worry about right now unless you are concerned and you'd like a second opinion ...Read more
Is stable bilateral frontaoparietal white matter t2w/flair hyperintense signals, probably chronic microvascular ischemic changes called mild stroke?
Result for my brain MRI -asymmetric decreased attenuation in the left basal ganglia, variant dilated perivascular spaces or punctate chronic lacune. ?
MRI report: This is language used in radiology to describe what they see. Ordinarily, they cannot distinguish a small stroke (lacune) from a perivascular space. A "puntate lacune" though is very small. It is probably just the side view of a blood vessel (aka perivascular). Do you smoke? Do you have high blood pressure? Do you have diabetes mellitus? Atrial fibrillation? These are stroke risk factors. ...Read moreSee 1 more doctor answer
MRI scan shows two small focal flair hot spots in either frontal lobes subcortically. Mild peri ventricular gliosis. Age related mild diffuse atrophy.
Probably not...: ...significant. A few small lesions can be seen in many patients without an underlying problem. If there is any concern, then a repeat MR in 4-6 months can be performed. Without any interval change, then you should not worry. However, atrophy at your age is more worrisome and not common, and your Doctor should examine you closely for any underlying cause. ...Read moreSee 1 more doctor answer
Typo: This is probably a secretarial error for "calcified granuloma with focal caseation". ...Read more
Skin biopsy result: superficial to mid dermal perivascular lymphocytic infilitrate with focal basal vacuolar changes.does thismean allergic vasculitis?
Need data: Is it primary or secondary fsgs. In addition how much protein is in the urine and what is the current kidney function? If the kidney function is significantly depressed the prognosis is poor. If there is more than 4000mg protein in the urine the prognosis is poor. Primary fsgs has a worse prognosis than secondary fsgs. Follow up with a nephrologist for appropriate treatment. ...Read more
Are Few tiny scattered nonenhancing T2/T2 FLAIR hyperintensities involving periventricular/ subcortical Zones supratentorial compartment bilat normal?
MRI: You can talk to your doctor about what this finding means in the context of your clinical picture, but usually what you are describing is an incidental, age-related finding that is probably of not much concern. ...Read more
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