Doctor insights on:
Focal Lobular Carcinoma In Situ
Also called lobular: Neoplasia...It forecasts that you will develop a breast cancer in either breast. Some used to do "mirror" biopsies. Others contemplate bilateral mastectomy. Lcis is a risk not a cancer, but the lobular invasive cancer can pose detection problems. Discuss this with a breast cancer team. I would watch very carefully. Lobular cancer makes up only 15% of invasive cancer. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Yes BUT: We need to consider that this is probably lobular "neoplasia" vs. Cis. That being said we still feel this is marker of increased cancer risk. We shouldn't neglect putting together fam history, other risk factors, limitations & risks in imaging, etc before discounting antihormonal therapy and rarely surgery. Many do choose close follow-up. Natural treatments may be incorporated with sufficient data. ...Read more
What are the causes of breast and arm pain after having biopsy with lobular carcinoma in situ diagnosis?
LCIS : Lobular-carcinoma-in-situ (lcis) is a microscopic finding on breast biopsy that is associated with an increased risk of breast cancer in either breast of those affected. It is silent in that it causes no symptoms. Therefore, your breast & arm pain is unrelated to the diagnosis. Perhaps the pain is related to the biopsy procedure itself. If so, it should resolve pretty quickly. ...Read more
Biopsy: The only way to make a diagnosis of ilc is by biopsy (usually needle biopsy). The problem with ilc is that it often does not show up on a mammogram or sonogram until it is large or a lump can be felt. That is why the diagnosis of ilc is often made later than other types of breast cancer. ...Read moreSee 1 more doctor answer
Good: Lobular breast cancer is more frequently multifocal and bilateral than ductal carcinoma. However, with mastectomy (lumpectomy may not be sufficient) and sentinel lymph node biopsy, with follow-up hormone therapy and/or radiation should yield a good outcome, depending on the grade and stage of the cancer. Stage is most important, along with hormone receptor status. ...Read moreSee 1 more doctor answer
Is mastectomy good for an invasive & in situ lobular carcinoma, stage 1b, sbr grade 2, 8 mm in size with good margins except anterior margin 1.5mm ?
Concern: The 1.5mm margin anteriorly is the only margin that gives me concern. For patients undergoing lumpectomy, obtaining at least a 2mm margin is associated with a decreased risk of recurrence. It would not be usual practice to take you back to surgery for a re-excision of this margin, however. ...Read moreSee 1 more doctor answer
No: Although both are breast cancers they are different in the significance attached to them. Lobular carcinoma is more likely to be larger, lymph node positive and estrogen positive then invasive ductal. A study in the ann surg oncol. 2010 jul;17(7):1862-9. Epub 2010 feb 17 suggests that invasive lobular carcinoma has a better prognosis stage for stage than invasive ductal carcinoma. ...Read more
Stage-Dependent: Breast cancers are staged based upon the size of the cancer, lymph node or distant organ involvement, direct extension to the skin or chest wall muscles, and unique molecular features of the tumor. Published rates of 5-yr survival (http://www.Cancer.Org/cancer/breastcancer/detailedguide/breast-cancer-survival-by-stage) vary quite a bit based on these variables, between 15%-93%. ...Read moreSee 1 more doctor answer
What is the survival rate for stage 3 invasive lobular carcinoma? Possibly has been there for 3-4 years undetected.
5 year: survival rate is approximately 70%.Get a more detailed answer ›
I have invasive lobular carcinoma, stage 2b, grade 2, spread to 1 lymph-node. Estrogen + , her2 - should I consider genetic testing?
Yes, please: Breast cancer at age 33 meets criteria for brca testing. The results may significantly impact one's surgical treatment decision (best to do before radiation therapy, since this would be unnecessary if one opts for mastectomy). That said, without any other risk factors, the statistical probability of being brca (+) is not that high. Please see a genetic counselor. ...Read more
The drug is taxotere (docetaxel) and cyclophosphamide used in chemo due to early stage of invasive lobular carcinoma does side effect cause insomia , depression?
Chemo and cancer: Dealing with cancer and its treatment is not something easy to do in many cases. Not only it is affecting your physical condition, emotionally, you can also develop anxiety, depressed mood, depression etc through out the battle. The chemo themselves do not give you insomnia. However, steroids are given prior to chemo, and this can cause insomnia. Depression/anxiety cause insomnia too. ...Read more
Depends: Depends on where this diagnosis was made. Is a non-invasive disease. Ductal carcinoma in situ of the breast is treated with lumpectomy and sometimes hormone therapy & radiation. Lobular carcinoma in situ of breast is treated as a benign pre-cancerous lesion. Cancer in situ of the colon treated as an early cancer with surgery. Gynecologist can answer this for a cervix lesion. ...Read moreSee 1 more doctor answer
Since no one has: Answered in a week, i think it is because like me, they do not know what cin is. We all know that carcinoma in situ means the cancer is superficial, not invading through a structure, and generally conveying risk of becoming invasive cancer. This is most prevalently used in breast cancer. However, i cannot contrast to cin. I do not know what that is. ...Read more
Unfortunately High: Anal carcinoma in situ is a rare pre-cancerous condition that often will recur. It may be associated with HIV and is usually directly caused by hpv. Sometimes close observation by anal "mapping" every 3-4 months is enough with small operations to remove any new lesions as needed. In other instances, treatment with imiquimod, laser therapy or radiation therapy might be recommended. ...Read more
Good question: And difficult to tell sometimes. The most straightforward way to put it is that a benign neoplasm will never turn into an invasive malignancy within your lifetime. Cis will eventually turn into one. But, because we don't live forever, cis might not turn into a malignancy during one's lifetime anyway. Pathologists can usually, but not always, tell the difference by microscopic cell exam. ...Read more
Depends on where this diagnosis was made. Is a non-invasive disease. Ductal carcinoma in situ of the breast is treated with lumpectomy and sometimes hormone therapy & radiation. Lobular carcinoma in situ of breast is treated as a benign pre-cancerous lesion. Cancer in situ of the colon treated as an early cancer with surgery. Gynecologist can answer this ...Read more
Means localosed in place. Medical terms is for carcinoma "localized and did not spread out" it is really description of precancerous condition with bad name that disturbs many patients. Carcinoma in situ is not a killer. If left untreated will develop into invasive cancer ...Read more
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