Doctor insights on:
Focal Ductal Carcinoma In Situ
"in place": Ductal carcinoma in situ (DCIS) of the breast is a breast cancer which has started in the ducts of milk glands (as most breast cancers do) but not yet invaded beyond that into the fat of the breast. Untreated, it has a high likelihood of becoming invasive breast cancer, a potentially fatal disease. Treated DCIS has a high cure rate. Some with DCIS benefit from taking med to prevent 2nd cancer. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Viral insertion: DCIS is the earliest phase of transformation to malignancy developing in the ductal system before invasion into parenchyma has occurred. It is defined on mammo by clustered microcalcification. In general the long terminal repeat of the MMTV viral genome enters the ductal cell to initiate transformation. with time the cells become aggressive and invade basement membrane helped by the EBV virus ...Read more
INVASIVE or DCIS?: These terms are incongruous: dcis is, by definition, breast cancer that has not "broken out" of the ducts and entered the adjacent supportive tissue of the breast; invasive, or infiltrating ductal cancer, by definition, has. The treatment of these 2 diseases is quite different since there is a risk of systemic disease with the latter. Please clarify, thanks. ...Read moreSee 3 more doctor answers
Genetic mutations: This is mostly a random event. There's a natural instability in the human genome even if you are never exposed to anything that's obviously a mutagen. The other factors that place you at risk for breast cancer (nulliparity, brca1 / brca2 mutations, etc.) are risk factors here, but no woman (and actually no man either) is immune. ...Read more
Is ductal carcinoma in situ really breast cancer? Can lifestyle, nutrition or supplements affect its course or occurrence?
Precancerous: Carcinoma in-situ is just one step short of cancer. There is no scientific evidence for or against life style changes altering the course of in-situ lesions. You may engage in life style changes that promote a healthy life style but should not omit conventional treatment. Steve jobs low grade cancer became fatal while he tried to treat it by alternative methods. See your doctor. ...Read moreSee 4 more doctor answers
What is the meaning of multifocal ductal carcinoma in situ, left breast and right subdural hematoma?
cancer and clot: Multifocal means mutiple seperate sites of cancer cells in the ducts or tubes of the breast. In situ means the cancer has not spread outside the ducts, into the surrounding breast tissue. In this instance the problem is in the left breast. Subdural hematoma is a blood clot between the brain surface and the membrane (called dura) covering the brain. In this instance the clot is the right side. ...Read more
Report of biopsy reads (in part):invasive ductal carcinoma with 'focal squamous differentiation' does this mean in fact there are squamous cells pres?
It depends: Tumors that are grade 3, or that have a high "proliferation rate", may spread more quickly than grade 1 or 2. Tumors that are er- (estrogen receptor negative) or her2+ spread more quickly than other types. Inflammatory breast cancer of any type can spread in days; the other types of invasive ductal carcinoma generally take months. ...Read moreSee 1 more doctor answer
Depends: Not all breast cancers are the same and many other factors help to predict better or poorer outcomes such as tumor grade, # of positive lymph nodes, estrogen receptor status, her2neu status, etc. A score called oncotype DX based on genetic profiling of the cancer helps define prognosis also and tailor decisions as to the best and most beneficial treatment to use. ...Read more
Most cancers cause: higher body temperatureGet a more detailed answer ›
Who said that???: That is the most common category of breast cancer, so i'm not sure why anybody would say such an absurd thing. It is curable if found early but it kills thousands of women every year. Ask the husband who lost a wife or the child who lost a mother if they think it's no big deal. ...Read more
Breast cancer: Ductal carcinoma in-situ is the earliest stage of a breast cancer. It is also referred to as dcis or non-invasive breast cancer. Dcis is when the cancer cells are growing within the breast ducts. At this stage, it is usually not palpable on physical examination. It is usually discovered where there are abnormal microcalcifications seen on a mammogram. ...Read moreSee 1 more doctor answer
Depends on grade: The level of chromosomal aberrations in infiltrating ductal carcinoma is correlated with the grade of the cancer cells. "grade" means the microscopic appearance and corresponds with how closely the cancer cells try to form normal breast structures. High grade or poorly differentiated infiltrating ductal carcinomas tend to have more chromosomal abnormalities than non-high grade carcinomas. ...Read more
Stage-Dependent: Breast cancers are staged based upon the size of the cancer, lymph node or distant organ involvement, and unique molecular features of the tumor. Published rates of 5-yr survival (http://www.Cancer.Org/cancer/breastcancer/detailedguide/breast-cancer-survival-by-stage) vary quite a bit based on these variables, between 15%-93%. The type of cancer (ductal, lobular, etc) doesn't impact survival. ...Read more
Depends on where this diagnosis was made. Is a non-invasive disease. Ductal carcinoma in situ of the breast is treated with lumpectomy and sometimes hormone therapy & radiation. Lobular carcinoma in situ of breast is treated as a benign pre-cancerous lesion. Cancer in situ of the colon treated as an early cancer with surgery. Gynecologist can answer this ...Read more
Means localosed in place. Medical terms is for carcinoma "localized and did not spread out" it is really description of precancerous condition with bad name that disturbs many patients. Carcinoma in situ is not a killer. If left untreated will develop into invasive cancer ...Read more
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