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Doctor insights on: Fluoxetine Citalopram

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What are the differences between fluoxetine and citalopram?

What are the differences between fluoxetine and citalopram?

They are similar: Fluoxetine and citalopram are both selective serotonin reuptake inhibitors so they are in the same class of medicines. Fluoxetine is the oldest medicine in the class and has a long chemical half-life. Citalopram is much newer, has a shorter half-life and fewer side effects. They are both used to treat depression, anxiety and some other illnesses. ...Read more

Dr. Heidi Fowler
1,057 Doctors shared insights

Fluoxetine (Definition)

Fluoxetine (brand prozac) is an antidepressant in the class known as serotonin selective reuptake inhibitors aka ssris. Fda approved in 1987 for the treatment of major depressive disorder. Subsequently approved for obsessive compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. Significantly safer and much better ...Read more


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Is Prozac (fluoxetine) fast acting then citalopram? Would Prozac (fluoxetine) cause less side effects then the citalopram?

Is Prozac (fluoxetine) fast acting then citalopram? Would Prozac (fluoxetine) cause less side effects then the citalopram?

NO: Prozac (fluoxetine) is not faster or slower acting than any other antidepressant. They all take about the same amount of time. There is no quick fix. ...Read more

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Is tenderness in the skin due to citalopram or fluoxetine anything to be worried about?

Is tenderness in the skin due to citalopram or fluoxetine anything to be worried about?

Not necessarily: First, I am not sure if those medications are the source of your pain. However, if they are and the pain is to much then stop the medication only after you speak to the prescribing physician. ...Read more

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Should I wait for however long it takes for the citalopram to get out of my system to start fluoxetine?

What did your: Physician/ psychiatrist say? No, you don't have to have a drug holiday before changing from citalopram to fluoxetine. ...Read more

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Does Prozac (fluoxetine) cause side effects? Is it better to take then citalopram?

Does Prozac (fluoxetine) cause side effects? Is it better to take then citalopram?

Possibly: All medications have potential side effects, although in general, they seldom occur, and if they do, are mostly manageable. Every event that happens during the pre marketing drug trials gets listed as a side effect, even if unrelated to the drug. Discuss your concern with your prescriber to hear what he or she has seen with use of the agent and learn why you need this drug in the first place. ...Read more

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I am currently taking fluoxetine, but have read about the side effects and would like to know more about the alternative citalopram. Thoughts?

I am currently taking fluoxetine, but have read about the side effects and would like to know more about the alternative citalopram. Thoughts?

Similar side effects: Side effect profile is very similar except in my experience fluoxetine may be more likely to increase anxiety and insomnia. Citalopram may have less potential for sexual side effects as well. ...Read more

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Should I wait until citalopram is out of my system to start fluoxetine cause it says they can interact or does that mean if they are taken together?

Consult provider: The provider directing this change should advise you on this, but if you must decide on your own - play it as safe as possible. Even for your own ability to evaluate the new drug, it will be clearer if the old one is not clouding the water. But the doctor is responsible and needs to be involved if possible. Best! ...Read more

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Took citalopram for 3 days off now cause had all types of side effects. Now on fluoxetine but haven't started do I need to wait or is it ok to start?

Took citalopram for 3 days off now cause had all types of side effects. Now on fluoxetine but haven't started do I need to wait or is it ok to start?

Go ahead and take it: You should start the drug. You might want to check with your doc first, by telephone, but there is no need for you to suffer in the meantime. These are generally pretty safe drugs. Call 911 if you have thoughts of hurting yourself. Otherwise, I bet you will feel better after you take the Fluoxetine. ...Read more

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Citalopram off, on fluoxetine now, Would side effects from other med go away when can Itake new med? Didn't take other med today so when should start?

Great questions.: Ideally these should have been answered by the prescribing physician. Not knowing specifically which side effects you were having I can't really comment on that, but usually it is not recommended that you suddenly stop taking one drug to allow a "wash out" period, because you could have unpleasant withdrawal symptoms. Review the materials you got from your pharmacy, and if not helpful call your MD ...Read more

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I was only on citalopram for 3 days and on fluoxetine it won't do nothing when start this fluoxetine will it? Cause I had side effects to citalopram?

Can't predict: Some can handle one SSRI but not others, some can't do well w/ any. It's case by case. Follow instructions carefully and if you are not happy - ask for guided taper off. Don't do it yourself - ever - if possible. Consider non-pharma CBT Therapy. Learning life skills can be more helpful to some. Best wishes! ...Read more

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Have headache from citalopram is this still side effects from it? But I have switched to fluoxetine now when can expect to go away?

Medicine half life: It is possible this is still a side effect of the old medicine, it is possible it is not a side effect. I would give this a week or so, it takes time for medicines to wear off. Hopefully the new medicine does not cause the same symptom. ...Read more

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If still have itching from citalopram how would I know if I am allergic to the fluoxetine? Cause took fluoxetine and itched has be from citalopram.

If still have itching from citalopram how would I know if I am allergic to the fluoxetine? Cause took fluoxetine and itched has be from citalopram.

The best way to: Tell would be to go off one drug have the itching stop completely and the start the new drug and see if the side effect returned, However, with medications such as the antidepressants that take so long to work that is not always practical. If the itching continues to improve then it is likely that you are not allergic to fluoxetine, If it stays they same or worsens after a week then you may be, ...Read more

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How long for side effects or allergic reaction to the fluoxetine if just took it this morning? Cause still have side effects of citalopram.

How long for side effects or allergic reaction to the fluoxetine if just took it this morning? Cause still have side effects of citalopram.

Can't be sure: It depends on the type of reaction. If this was the first time you took fluoxetine, I would not expect allergic sensitization to develop until about 10 or more days later. If you have GI upset from it, then the reactions can happen within 15-30 minutes but others can occur hours later. ...Read more

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When I don't take Citalopram 20 or Fluoxetine 20 I'm impatient most of time everyday. Is this sign of depression and whether I should continue it?

When I don't take Citalopram 20 or Fluoxetine 20 I'm impatient most of time everyday. Is this sign of depression and whether I should continue it?

Depends on you: SRIs impart patience, some call it zombiism, so we can cope with the unnatural stressors of civilization. SRI's were originally meant to be used for 6 mos max as a bridge back to well being. Were you impatient before? If not then this is a withdrawal effect & the sooner you stop the better off you'll be. Until age 27 the brain has the ability to reverse alterations caused by drugs, after that??? ...Read more

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I'm taking 200mg of sertraline a day, yet it doesn't help anymore, the same happened when I took citalopram and prozac, (fluoxetine) what others could I try?

I'm taking 200mg of sertraline a day, yet it doesn't help anymore, the same happened when I took citalopram and prozac, (fluoxetine) what others could I try?

Antidepressants: Your psychiatrist could consider augmenting your sertraline with other agents including abilify, (aripiprazole) wellbutrin, l-methyl folate, etc. Could consider changing to Effexor or cymbalta. For sure, psychotherapy needs to be part of your treatment rather than hoping for pharmaceuticals to manage the entire problem. Best wishes. ...Read more

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What do I do if the fluoxetine causes headaches like the Citalopram? Just take Tylenol (acetaminophen) or ask Dr to see what they can do?

What do I do if the fluoxetine causes headaches like the Citalopram? Just take Tylenol (acetaminophen) or ask Dr to see what they can do?

Tylenol, (acetaminophen) other drug: You can take anything you'd like for the headache, perhaps with the exception of ultram (with caution), but talk to your doctor about a different class of drug for you depression ...Read more

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on citalopram for 3 days but have side effects, and increased anxiety and panic attacks u think a dr could change me to Prozac (fluoxetine) since its fast acting?

on citalopram for 3 days but have side effects, and increased anxiety and panic attacks u think a dr could change me to Prozac (fluoxetine) since its fast acting?

SLOW IT DOWN: May need to just reduce the dose a little of the citalopram. There is no faster acting medication and Prozac (fluoxetine) would not be faster. When you have anxiety you need to go on medication very slowly to avoid increase in anxiety. ...Read more

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What is the difference between Prozac (fluoxetine) and celexa?

What is the difference between Prozac (fluoxetine) and celexa?

Prozac (fluoxetine) was prototype: Prozac or fluoxetine was the first selective serotonin reuptake inhibitor. Later ssri's that were developed worked on other subtypes of the serotonin receptors in the brain and thus in theory had less side effects.
Also they were metabolized differently by the liver. Therefore duration of action or interaction with other medications differed.
An example would be different degree of sexual problems. ...Read more

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Switching from celexa to prozac (fluoxetine). What can I expect?

Celexa (citalopram): Under supervision, most likely u will tolerate the switch well. ...Read more

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Prozac (fluoxetine) is making me sick. Do you think I should switch back to celexa?

Prozac (fluoxetine): Not sure why u switched from Celexa to prozac, (fluoxetine) but u need to talk to your prescribing doctor first. ...Read more

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Was on celexa for 13 years. Titrated to Prozac (fluoxetine) but caused bad side effects. Can I go back to celexa and be normal again or will it not work the same?

Data not available: The only ssri for which we have such data is prozac (fluoxetine). If a person has been on Prozac (fluoxetine) and it failed to work and they stopped it, then there was a 90% chance of it working when it was readministered. That type of data are not available for celexa. Having said that however I suspect that it is likely the same case for the other ssri's based on my clinical experience. Best wishes. ...Read more

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I have to get off of venlafaxine, its my call when, is there more of a success rate with Prozac (fluoxetine) or with celexa?

I have to get off of venlafaxine, its my call when, is there more of a success rate with Prozac (fluoxetine) or with celexa?

Work w/ a provider: I should only be your "call" to decide to begin the process - a pro needs to determine the pace for your safety. Serotonin-syndrome is no joke. Also, while some do find a switch among SSRIs to be helpful - each has a list of side effects and response seems to be unique for each person. While you search - also try som CBT therapy - it may be the best bridge or alternative. No side effects at all. ...Read more

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Does the medication celexa cause weight gain? I was on it for three years and now I'm prozac (fluoxetine). Could these two medications cause weight gain?

Yes: Although Celexa is labeled as weight neutral and Prozac (fluoxetine) is weight negative. I have actually seen weight gain as well sometimes with these meds. A lot depends on the patient their own personal reaction to medicines. Check with your doctor to see if another medicine would be better and less likely to cause weight gain for you. ...Read more

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Which is better for anxiety or depression. Celexa or prozac (fluoxetine)? Which has fewer side affects?

It depends: Both medis are in the same class, so side effect profiles are similar. Both are good agents for depression and anxiety. However individual patient respond to meds differently. Hope this helps. ...Read more

Dr. Alan Ali
921 Doctors shared insights

Citalopram (Definition)

Citalopram is a ssri medication used to treat anxiety and depression disorders, it's also used to treat ptsd and ocd. It takes 4 to 6 weeks to be fully effective. Side effects; sedation, minor temporary stomach issues, delayed orgasm in males and rarely weight gain. It is ...Read more


Dr. Alan Ali
778 Doctors shared insights

Prozac (Definition)

Prozac is a serotonin reuptake blocker which is a kind of ...Read more