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Doctor insights on: Flumazenil Hepatic Encephalopathy

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What is hepatic encephalopathy?

What is hepatic encephalopathy?

Hepatic encephalopat: Hepatic encephalopathy is a condition of confusion or altered alertness due to inhibition of brain function. It is believed that this is related to insufficient metabolism of the liver and build up of chemicals that can be transmitted to the brain by the blood stream. In some cases, an elevated blood ammonia level correlates with this condition, but not always, and the role of ammonia is debated. ...Read more

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Dr. Michael DePietro
141 doctors shared insights

Encephalopathy (Definition)

Encephalon means brain, pathy means abnormal, so the full term means abnormal brain. I see the statement used by many of my colleagues, but it is not a diagnosis, ...Read more


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Has anyone survived hepatic encephalopathy?

Sure !: The encephalopathy can be treated by the treatment of liver failure and depeding on the cause and the state of the disorder can be reversed. ...Read more

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What is best anticonvulsant in ptn. With hepatic encephalopathy?

What is best anticonvulsant in ptn. With hepatic encephalopathy?

??PTN: I don't know what you mean by ptn. However, hepatic encephalopathy generally refers to the confusion that patients with cirrhosis develop. The sick liver is unable to clear toxins which then affect the brain. The patient will experience memory difficulties, difficulty with sleep, alterations in personality, and at its worse, it can cause coma. ...Read more

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Whats wernicke encephalopathy?

Whats wernicke encephalopathy?

Deficiency of B1: It is a neurologic syndrome caused by a deficiency of vitamin b1. It is mostly confined to those with severe malnutrition, classically patients with alcoholism. It damages areas of the brain concerned with balance, eye movements and memory so those with the syndrome have difficulty walking ( ataxia) memory problems, and ey movement abnormalities. ...Read more

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Whats the difference between hepatic encephalopathy and portosystemic encephalopathy?

Whats the difference between hepatic encephalopathy and portosystemic encephalopathy?

Hepatic encephalop: These are essentially the same. Portosystemic encephalopathy may occur in fulminant hepatitis caused by viruses, drugs, or toxins, but it more commonly occurs in cirrhosis or other chronic disorders when extensive portosystemic collaterals have developed as a result of portal hypertension due to the changes in the liver structure. It may also occur after portocaval shunts. ...Read more

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Is hepatic steatosis same as steatohepatitis?

Is hepatic steatosis same as steatohepatitis?

Not the same: "itis" means inflammation, so "steatohepatitis" is a liver inflammed in association with fatty infiltration. Steatosis just means fat has accumulated in the liver, without associated inflammation. A chronically inflammed liver is at risk for cirrhosis and liver cancer, so it is important to reverse steatohepatitis when possible (ie.Weight loss, correct diabetes & high cholesterol, stop alcohol). ...Read more

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Does hepatic encephalopathy cause short term memory loss?

Does hepatic encephalopathy cause short term memory loss?

Sort of: Hepatic encephalopathy can be associated with a variety of neurological symptoms from confusion and delirium to coma. Since confused patients may not be attentive it may appear they have short term memory loss. Once treated the mental status problems are reversible. ...Read more

Dr. Alan Ali Dr. Ali
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How does brain dysfunction occur in patient with hepatic encephalopathy?

Dr. Alan Ali Dr. Ali
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How does brain dysfunction occur in patient with hepatic encephalopathy?

Hepatic encephalopat: Nitrogenous waste products accumulate in the systemic circulation, such as Ammonia, which crosses the blood-brain barrier and is absorbed by brain cells which use ammonia to form Glutamine, which cause swelling of brain cells. ...Read more

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How is hypoxic ischemic encephalopathy treated?

How is hypoxic ischemic encephalopathy treated?

Hearing loss: Theoretically, hypoxia can affect any part of the brain, hence it is possible for auditory cortex be involved causing deafness. Not sure how often it occurs. ...Read more

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Wernicke encephalopathy disability treatable?

Wernicke encephalopathy disability treatable?

Yes: If diagnosed before permanent damage the disease is easily treatable with b1 vitamin supplementation. ...Read more

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Can morphine in a esld patient cause hepatic coma, renal failure and ultimately death?

Can morphine in a esld patient cause hepatic coma, renal failure and ultimately death?

No: Hepatic coma is from the buildup of toxins not being processed by the damaged liver...Which can poison the kidneys...And eventually result in death. Morphine or other narcotics may be given to an esld patient to reduce their discomfort as they are passing. ...Read more

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Can bloodletting help someone with hepatic encephalopathy?

Can bloodletting help someone with hepatic encephalopathy?

No. (?): "Bloodletting" refers to the ancient and long-discredited practice of bleeding someone to remove "evil humors" (another long-outdated concept). "Therapeutic phlebotomy" is used to treat diseases that cause overproduction of red blood cells or their constituents eg hemochromatosis, polycythemia vera, porphyria cutanea tarda. It is NOT indicated for hepatic encephalopathy. ...Read more

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Is cirrhosis terminal?

Is cirrhosis terminal?

Need more info: Cirrhosis can be "compensated" or decompensated-- like fluid build up in your abdominal cavity (ascites), confusion (hepatic encephalopathy), bleeding varices, liver cancer (hcc). You could have easy bruising, fatigue and jaundice (elevated bilirubin) as well. With some of the above, life expectancy can be lower, but transplant can fix this! see a liver doctor who can discuss the above with you. ...Read more

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What is best anti convulsant drug for patient with hepatic encephalopathy?

No one best: There is no one best drug but a physician will try to select one by balancing adequate seizure control, ease of use, other medical problems, with minimal risk of causing additional liver problems. Keppra (levetiracetam) (levetriacetam) is a potential choice with low risk of liver injury but there is no one best choice. ...Read more

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Why is chlordiazepoxides, diazepam, clofibrate, barbiturates contraindicated in renal failure?

Why is chlordiazepoxides, diazepam, clofibrate, barbiturates contraindicated in renal failure?

Impaired elimination: All drugs that are taken are eventually metabolized and eliminated from the body. Although liver enzymes perform the bulk of metabolizing of these agents, elimination of the drug and their metabolites relies, to varying degrees, on the kidney. If the kidneys are failing, elimination is impaired, and a toxic buildup of the drug and/or its metabolites is possible. ...Read more

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Can echogenicity of hepatic parenchyma is borderline mild mean auto immune hepatitis?

Can echogenicity of hepatic parenchyma is borderline mild mean auto immune hepatitis?

Fatty liver likely: Lots of substances may "infiltrate" the liver & increase echogenicity (sound waves bounce off liver better). Fatty liver is most common--due to diabetes, high cholesterol, obesity, drinking too much alcohol. Lose weight & stop alcohol consumption if these are your problems. Fatty liver with abnormal liver functions (blood tests) is however considerably more concerning than just an echogenic liver. ...Read more

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What is chronic liver parenchymal disease with cirrhosis; varices and ascites?

What is chronic liver parenchymal disease with cirrhosis; varices and ascites?

This sounds serious: To translate, you have liver cell damage and scarring (cirrhosis), which caused abnormally elevated portal vein pressures which caused venous distention in esophagus (varices). You also developed fluid in abdominal cavity, because of the high portal vein pressure. This imaging study is showing advanced stage of liver disease. You must get a specialist to treat you. ...Read more

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Pathophysiology of liver cirrhosis?

Pathophysiology of liver cirrhosis?

See below: Scar tissue in the liver as a result of different kinds of injuries. The significance is related to the chronicity for the injury and especially whether the injury is ongoing. ...Read more

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Is hepatic steatosis caused by alcoholism?

Is hepatic steatosis caused by alcoholism?

It can be: Hepatic steatosis (fatty liver) can be caused by both alcohol use and having an unhealthy diet & being obese. In fact, the most common cause of fatty liver disease in the US is poor diet & lifestyle. The disease that includes this cause is NAFLD (non-alcoholic fatty liver disease). ...Read more

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Dr. Bruce Weisbrot
509 doctors shared insights

Flumazenil (Definition)

Flumazenil is a long-acting benzodiazepine which is a kind of sleep-inducing drug ...Read more


Dr. Robert Rahimi
56 doctors shared insights

Hepatic Encephalopathy (Definition)

A condition in which liver failure causes symptoms ranging ...Read more