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Doctor insights on: First Trimester Serum Screening

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What is a first trimester screening for a fetus?

What is a first trimester screening for a fetus?

Blood and U/S tests.: First trimester screen for any pregnancy includes a sonographic examination to determine plurality, basic fetal anatomy, gestational sac location, fetal viability and gestational dates - as well as blood tests (hcg, papp-a, maternit21/harmony tests) to determine the risk for down syndrome, fetal growth restriction, preeclampsia (uterine artery dopplers), preterm birth (cervical length). Nicolaides. ...Read more

Dr. Milton Alvis Jr
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Screening (Definition)

Examples are: colonoscopy for colon polyp or cancer; mammograms for breast lesions or cancer; psa a blood test that could indicate enlargement of cancerous prostate tissue; blood sugar or hemoglobin a!c for diabetes. Many think that scanning the whole body will pick up a cancer--in all likelihood, it will not. There also is no good blood test, yet, ...Read more


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What is first trimester screening and maternal fetal medicine?

What is first trimester screening and maternal fetal medicine?

Ob terms: 1st trimester screening are any tests done during a pregnancy during the first 12-14 weeks of pregnancy. This can include ultrasounds. blood tests and others. Maternal fetal medicine is a subspecialty of obstetrics. It's also often called "perinatology". These are obstetricians who go on to do additional training in the management of high risk pregnancies. ...Read more

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Should i be worried if soft markers were found in anatomy scan when harmony, AFP and first trimester screening were very low risk?

I'm sure it's hard : Not to worry till your OB can gather enough additional information to confirm or rule out a problem. However, it also assures you that you & your baby are receiving excellent medical care & that all needed tests &/or referrals will be offered to you in a timely fashion. Try to stay positive & healthy. You may not have. Been able to process everything your OB said at first, so ask him/her again. ...Read more

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Already had harmony test, afp, first trimester screening and they were all very low what might a dr suggest if soft markers are found on anatomy scan?

Reassurance!: If all that's found is a soft marker, and your screening and cell free dna results are normal, the most likely answer is that the soft marker is a normal variant. However if there is a finding consistent with a birth defect, that might merit further investigation, such as diagnostic testing within amniocentesis. ...Read more

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Which is a better predictor of Down syndrome during the first trimester screening, low papp-a or high hCG levels? Or the ratio between the two values?

Which is a better predictor of Down syndrome during the first trimester screening, low papp-a or high hCG levels? Or the ratio between the two values?

Four tests: A combination of four tests, quad screen, is done twice as a screening test for down syndrome. See this site for more info. http://www.mayoclinic.com/health/quad-screen/my00127. ...Read more

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I had a normal first trimester screening and harmony prenatal test. Is an AFP blood test necessary? Can it come back high risk?

I had a normal first trimester screening and harmony prenatal test.  Is an AFP blood test necessary?  Can it come back high risk?

The msAFP is: To assess the risk of open neural tube defects i.e. Spina bifida, which is not tested by harmony or the first trimester screen. It is up to you if you would like to be screened for ntds. Keep in mind that, if detected, these defects can be repaired by a skilled pediatric neurosurgeon while the baby is still inside you. Speak to your obgyn and make an informed decision. Hope this helps. ...Read more

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If the 1st trimester screening for Down syndrome was negative, how much does an echogenic focus at 20 week screening factor in?

If the 1st trimester screening for Down syndrome was negative,  how much does an echogenic focus at 20 week screening factor in?

Amniocentesis is key: If you had amniocentesis which did not reveal abnormalities consistent with .Down syndrome, then the only concern would be structural abnormalities, such as heart abnormalities. If you have not had amniocentesis, you should have it. ...Read more

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Fetal hb @ 6w2d. Doc didn't tell me # of BPM & i didn't ask but was only told to come back @ 12w to have the 1st trimester screening. Shoud i worry?

Fetal hb @ 6w2d. Doc didn't tell me # of BPM & i didn't ask but was only told to come back @ 12w to have the 1st trimester screening. Shoud i worry?

No: The presence of the heart beat is way more significant than the exact rate and the chances of miscarriage are much decreased. Your doctor would certainly be bringing you back sooner if the rate was not in a normal range. ...Read more

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My 1st trimester screening came back very low 1 in 3, 000. I just took the harmony genetic test. Is there any chance my risk can change to high risk?

My 1st trimester screening came back very low 1 in 3, 000. I just took the harmony genetic test. Is there any chance my risk can change to high risk?

Not likely: Your numbers are quite good. The 1 in 3000 is based on your first trimester screen which is a probability. The harmony test is based on the fetal dna in your blood. Therefore, it has a higher detection rate than the first trimester screen, and in theory could change--but not highly likely given your good numbers. ...Read more

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What heron does to baby in first trimester?

What heron does to baby in first trimester?

Heroin and Pregnancy: It is not good. But, at this point it does not matter. What matters today is that you get to your doctors, to the hospital or to a drug and alcohol treatment facility so that you can be safely detoxed and allowed to join the program with other women like you to help each other stay clean. There really and honestly is a solution to this problem and it requires action today. Please take this advice. ...Read more

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Serum (Definition)

Serum is the component of blood that does not contain cells or clotting factors. It does contain electrolytes an ...Read more