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Doctor insights on: Fingolimod

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Glatiramer acetate (copaxone) vs. Interferon?

Glatiramer acetate (copaxone) vs. Interferon?

See answer below: Both are used in rrms with similar efficacy levels. Copaxone (glatiramer) does not need blood monitoring and is administered as a subcutaneous sc injection daily. Side effects include injection site reactions. Interferons need lab work monitoring, can be a weekly injection into a muscle (avonex), every other day sc (betaseron) or three times a week sc (rebif). Most commo side effects include flu-like symptoms. ...Read more

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What new treatments are there for multiple sclerosis?

What new treatments are there for multiple sclerosis?

Define new...: First line therapies include: -interferon beta-1a (avonex) im once a week. -interferon beta-1a (rebif) sc three times a week. -interferon beta-1b (betaseron, extavia) sc every other day. -glatiramer acetate sc (copaxone) sc daily. Second line therapies include: -mitoxantrone (novantrone) IV q3months. -natalizumab (tysabri) IV q4weeks. -fingolimod (gilenya) PO daily. ...Read more

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Which is better? Interferon or tysabri (natalizumab)?

Which is better? Interferon or tysabri (natalizumab)?

NO contest: Tysabri (natalizumab) is the second most potent MS drug on the market, but it has a risk, as can potentially cause Progressive Multi-focal Encephalopathy, and possibly melanoma. Interferons are drugs of the past, and being phased out over time, due to lack of efficacy, but they are quite safe in most patients. ...Read more

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What exactly is a mental health check?

What exactly is a mental health check?

Wellness screen: A mental health check is brief screening of emotional, social and occupational functioning that is often done as a part of a annual medical check-up. Mental health checks are a good way of identifying people who have undiagnosed but very treatable mental health concerns. ...Read more

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Define health is wealth?

Definition: Good health, mental , physical & spiritual, leads to enjoyment of life to its fullest. Wealth without good health cannot provide any quality to your life. Thus goes this saying! health leads to wealth, but not vice versa! ...Read more

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I've read in healthtap about tecfidera, gilenya (fingolimod) and tisabry MS treatments. What's your opinion about interferon treatment (using rebif 44mg)?

I've read in healthtap about tecfidera, gilenya (fingolimod) and tisabry MS treatments. What's your opinion about interferon treatment (using rebif 44mg)?

Not first choice: Look, we are in a new age of treatment, and need to acknowledge that the older injectables were great to use, but the drugs you listed are far more effective, and avoid needles (except tysabri, (natalizumab) one infusion monthly) yet, risks are present with all three, and in comparison with rebif, absence of long-term safety data. If you are doing well, could stay on current med, but change if MRI is active. ...Read more

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Would you recommend Gilenya (fingolimod) or Tecfidera as choice for new oral meds for MS?

Reasonable, but...: It is a reasonable question; but, the answer is not that simple, maybe. I suggest you look at the National Multiple Sclerosis Society web site, where available meds are discussed. Both meds are outrageously expensive, even though the chemical in Tecfidera has been around for decades (arguably no justification for its cost). Tecfidera arguably has a better side-effect profile. Talk to your MD ...Read more

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Is tysabri (natalizumab) a treatment for ms?

Yes: This is a monoclonal antibody, infused once monthly, and is the currently most potent medication on the market for MS. In several cases, a deadly infection called PML has occurred with pts taking this medication, but blood tests can predict risk, and if positive can prompt the discontinuation of Tysabri (natalizumab).. Drug can be used early or late, but is approved for first line. ...Read more

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Please describe the most prevalent childhood disease?

Please describe the most prevalent childhood disease?

Asthma: The most prevalent chronic childhood disease is asthma. Prevalence is the total number of children with the disease at the current time. For asthma, the prevalence is about 10% of children. For childhood acute illnesses that go away after a short while, colds are the most common (usually caused by rhinoviruses). ...Read more

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Can od prescribe medicine?

DO?: Did you mean a do, doctor of osteopathy? If that's what you meant, then yes they can prescribe medicine. ...Read more

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Initial side effects of avonex (interferon beta 1a) (beta interferon 1a) for ms?

MS and AVONEX (interferon beta 1a): Avonex (interferon beta 1a) is often prescribed for ms.Side effects are mild1 flu like symptoms, headache and muscle pain are the most common side effects of avonex2 it can causeabdominal pain, toothache and dizziness most of the side effects are mild and do not need any treatment or can be treated easily. 3 unusual bruising or bleeding or frequent infections or chest pain can be serious and seek medical help asap. ...Read more

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Are imuran (azathioprine) & betaferon effective treatments for ms?

Are imuran (azathioprine) & betaferon effective treatments for ms?

Yes they can be: The evidence is stronger for beta interferons (avonex, Rebif and betaseron) than it is for immuran. Interferons are fda approved and immuran is not (for ms) they all have a modest but definite effect in reducing the number of attacks in remitting relapsing forms the effect varies from patient to patient. ...Read more

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What is lithium prescribed for ?

What is lithium prescribed for ?

Why Lithium: There are a number of reasons for prescribing lithium, some of which are off-label. Lithium is commonly prescribed to treat symptoms of bipolar disorder. Other reasons include assisting with anger management by decreasing explosive episodes. Another is to augment or boost the antidepressant effects from antidepressants. ...Read more

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Betaseron (interferon beta 1b) adverse reactions?

Betaseron (interferon beta 1b) adverse reactions?

Multiple..: 1) depression 2) allergic reaction 3) injection site necrosis http://www.Rxlist.Com/betaseron-drug/side-effects-interactions.Htm. ...Read more

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Cimzia (certolizumab pegol) 200 ? Uguale a humira?

Cimzia (certolizumab pegol) 200 ? Uguale a humira?

Similar medications: Cimzia (certolizumab pegol) and Humira both work by blocking tnf alpha. They are similar medications but not the same. They should not be used together. They both increase the risk of infection. They both increase the risk from tuberculosis. ...Read more

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Is the term frigid used anymore for women?

Is the term frigid used anymore for women?

Older term: This is an older term for women with an abnormal disinterest in sex or an inability to orgasm even during masturbation. Regardless of the nomenclature, sexual health in women may require counselling and treatment if the problem persists and is interferring with women's life. ...Read more

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How close in relationship is tecfidera & copaxone (glatiramer)?

How close in relationship is tecfidera & copaxone (glatiramer)?

VERY DIFFERENT: Entirely different chemical classes, with distinct different mechanisms of action, and outcome data. Both seem safe, Copaxone (glatiramer) tho is injected daily, causes lipoatrophy, hypertension, and injection reactions. Tecfidera may be tough to tolerate due to flushing, nausea, diarrhea, stomach pain. Copaxone (glatiramer) relapse reduction is 29%, but tecfidera, drops 44-52%, oral twice daily, no needles. Talk to doc. ...Read more