Doctor insights on:
Final Days Of Small Cell Lung Cancer
Is it true that small cell lung cancer is considered a sleeper cell where it only presents itself aggressively in the final stages? Making sense of dx
Interesting term: All cancers can display a wide range of behavior, from very slow, to very fast growing. This is true even of small cell cancer, which has a well-earned reputation of growing rapidly and spreading early, often before it's detected. I've never heard the term "sleeper cell" used in this field, but if it applies anywhere, this might be a reasonable description of all lung cancer, esp small cell. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
She was diagnosed with non small cell lung cancer stg. 4 and died 29 days later. Before she was diagnosed she seemed fine. How could this happen?
Small cell cancer: Most cancers have a volume doubling time of about 3 months, except small cell cancer. Problem with small cell cancer is that it goes fast, may have no symptoms initially and can go be in multiple organs the time it is diagnosed, and can include the lining of the heart and can cause fluid and compression of the heart. ...Read more
Rarely is cured.: It depends on the stage and if the cancer has spread. Small cell lung carcinoma is usually treated with chemotherapy and radiation. It is one of the most aggressive subtypes of lung cancer. Definitely consult with an oncologist, but patients with small cell should weigh the benefits of participating in treatment offered in clinical trials at university centers. ...Read more
Diagnostic test: First of all, a biopsy needs to be done to establish a diagnosis. Once is confirmed, then staging work-up needs to be done that include- ct scan; a bone scan and imaging for the head- MRI brain will be preferable than ct scan- if possible. Discuss further with your oncologist. ...Read more
Lung cancer: Small ("oat") cell lung cancer is distinguished by the fact that is has almost always spread beyond the lung when discovered and is therefore not surgically curable, but responds very well to initial chemotherapy. Now that the other common types are coming to be more treatable as well, "non-small cell" is giving way to more elaborate diagnostic schemes. Good luck ; keep up hope. ...Read more
Limited: Most with this diagnosis have less than 2 years of survival, unless found when small and peripheral so it can be removed! ...Read more
Hard to tell:
Small cell lung cancer is a rapid growing cancer, but the exact size change in a particular patient is often hard to predict. Several factors affect the growth of tumors in a person, including immune factors and genetic factors.
But in general, once small cell lung cancer is diagnosed, it is never just watched, so it is hard to see how fast it will grow. ...Read more
Neuroendocrine tumor: Primary lung lesions are comprised mainly of malignant cells of the bronchus or squamous cell cell and malignant cells of lung glandular tissue or adenocarcinoma of lung. The 3 rd tumor is neuroendocrine or small cell Ca. It is similar in structure and response to the carcinoid of bowel.Tumors other than mets are therefore classed as small cell and non small cell tumors. ...Read more
End of life: If small cell carcinoma is terminal, it means that all means of treatment have failed. Symptoms, including shortness of breath, fatigue, and pain will become more pronounced. This is the time to have comfort care measures in place to make the end as bearable as possible. Pain control at this point is critical. ...Read more
Yes: Small cell carcinomas may arise in many organs. They typically show evidence of differentiation toward certain glandular structures, called 'neuroendocrine' differentiation. Small cell cancers tend to be rapidly proliferating tumors, and thus may be treated initially with chemotherapy. ...Read more
How likely is it for someone who has never smoked or been around smokers to be diagnosed with small cell lung cancer?
Would you have symptoms of small cell lung cancer for 18 months prior to diagnosis, or does small cell grow too rapidly for this to happen?
Depends on the grade: After a biopsy, when small cell carcinoma is diagnosed, it is often given a "grade" by the pathologist (e.g., low-grade or high-grade) based on the appearance under a microscope. There are small cell cancers that can grow slowly, & only be discovered on screening CT scans (not causing any symptoms). Others cause symptoms & spread quickly (high-grade). Not all small cell cancers behave alike. ...Read more
Nsclc: First of all, a biopsy will need to be done to the lung mass/nodule not only to establish diagnosis but also to find the histology and genetic profile of the cancer. Then, complete staging work-up with pet/ ct scan need to be done to stage the cancer. The treatment will depend on the histology/molecular-genetic mutation status, stage, as well as overall condition and preference of a patient. ...Read more
5yr suvival bystage:
Ia = 49%
ib = 45%
iia = 30%
iib = 31%
iiia = 14%
iiib = 5%
iv = 1%
http://www. Cancer. Org/cancer/lungcancer-non-smallcell/detailedguide/non-small-cell-lung-cancer-survival-rates. ...Read more
One type of lung:
Cancer. It is not easy to explain. There are multiple subtypes within in this type. These are due to smoking and tend to spread locally as compared to early spread through blood for small cell cancer. See this site for more info.
http://www. Cancer. Gov/cancertopics/pdq/treatment/non-small-cell-lung/patient/page1. ...Read more
The stage and others: Will depend on the stage and other prognostic factors. In general, the 5 year overall survival for stage 1 is 60-80%., stage 2 is 40-50%; stage 3 is 10-23%, and stage 4 is less than 10%. These however are the statistics obtained when using regular cytotoxic chemotherapy. With more personalized and more targetted therapy-we are hoping the number will improve. ...Read more
Often cures: Surgery is the standard of care for stage I and ii lung cancer in the physically fit patient, and should be considered as an option in many patients with stage iiia. Often can be done minimally invasively thorascopically or with a robot. Recovery varies with the level of invasiveness. Lung surgery has best outcomes by a board certified thoracic surgeon. ...Read more
Robot or VATS: Optimal lung cancer surgery, in appropriate candidates, is anatomic lobectomy (part of lung) or pneumonectomy (whole lung). Complete lymph node sample or dissection is integral part of case. Traditional centers use thoracotomy as primary approach. Modern minimally invasive approaches include vats and robotic techniques. Optimal lung cancer treatment is by comprehensive multidisciplinary approach. ...Read more
Not enough space: Let's see: most common category of lung cancer, often but not always tobacco related, treated with surgery if possible but radiation and chemo are often used as well. I suggest you visit the national cancer institute website. It's has good info regarding all kinds of cancers. ...Read more
Deoxygenated blood enters the lungs from the right side of the heart and travels to the lungs. When you inspire, oxygen flows into the lungs, transverses the capilliares and attaches to hemoglobin down a gradient. At the same time, co2 diffuses into the capilaries and is expelled with exhalation. Oxygen rich blood then flows to the left side of the heart and into the ...Read more