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Doctor insights on: Fibrous Dysplasia Face

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I have mazabraud syndrome. Will fibrous bone dysplasia of the femoral neck cause permanent disability?

I have mazabraud syndrome. Will fibrous bone dysplasia of the femoral neck cause permanent disability?

Varies.: the location, extent and progression of the dysplasia varies. BUT it occurs after the bones are already formed. The femoral neck is a relatively bad spot for it but it is ONE spot. so, there are limits on the effect of it in isolation. Furthermore the muscle myxoma's vary but since some become malignant they all have to be removed. ...Read more

Dr. Peter Ihle
1 doctor shared a insight

Dysplasia (Definition)

Abnormal cells which may be pre-malignant, but can also result ...Read more


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Superficial fragments of oesophagel mucosa lined by stratified squamous epithelium showing mild acanthosis and papillomatosis. Please explain?

Superficial  fragments of oesophagel mucosa lined by stratified squamous epithelium showing mild acanthosis and papillomatosis.  Please explain?

Fancy med talk: I just looked up in a medical dictionary: acanthosis means a thickening of a layer of the mucosa of the esophagus. This can be seen with chronic inflammation ( like with reflux disease). The word papillomatosis refers to papilla or projection of tissue sticking out. This can occur if there is chronic injury to the tissue and regeneration. Please ask your GI doctor to take the time to review this. ...Read more

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What does this mean? Inverted papilloma with dysplasia and foci of in situ invasive squamous cell carcinoma (transitional)?

What does this mean? Inverted papilloma with dysplasia and foci of in situ invasive squamous cell carcinoma (transitional)?

Premalignant: An inverted papilloma is a tumor in which surface epithelial cells grow downward into the underlying supportive tissue. It may occur in the nose and/or sinuses or in the urinary tract (bladder, renal pelvis, ureter, urethra).. With dysplasia and in-situ squamous Ca this would probably be a premalignant sinus carcinoma bordering on squamous cell Ca needing resection. ...Read more

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Epithelial cell abnormality, High-Grade Squamous Intraephithelial lesion, atypical glandular cells and sever dysplasia. What should my concern be?

Epithelial cell abnormality, High-Grade Squamous Intraephithelial lesion, atypical glandular cells and sever dysplasia.  What should my concern be?

Pap smear: Is this the result of your pap smear? if yes, then it means moderate or severe cervical intraepithelial neoplasia or carcinoma in situ, which in some cases could lead to cervical cancer. you need Colposcopy and possible biopsy. Talk to your Gynecologist regarding a treatment plan. ...Read more

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Please interpret this tissue biopsy. Fibrous pericardium with granulation tissue and fibrinous exudate. There is mild fibroplasia?

Please interpret this tissue biopsy. Fibrous pericardium with granulation tissue and fibrinous exudate.  There is mild fibroplasia?

Healing: The pericardium has been injured in some way, perhaps by surgery or there may be a healing infection. What is means most of all is there isn't tumor. ...Read more

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Help me interpret vulvar biopsy. Focal squamous atypia. Ki-67 shows mild increase cell proliferation focal vin can't be excluded. Lichen sclerosis?

Help me interpret vulvar biopsy. Focal squamous atypia. Ki-67 shows mild increase cell proliferation focal vin can't be excluded. Lichen sclerosis?

Nothing serious yet: This report suggests slightly abnormal changes (atypia & increased cell proliferation) which can be a reaction to irritation but there is no definitive evidence of precancerous change (VIN). In short there is nothing to worry about right now unless you are concerned and you'd like a second opinion ...Read more

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I was Diagnosed with Severe Dysplasia(CIN3)involving ectocervical squamous mucosa and fragments of benign endocervical glandular epithelium. ?

I was Diagnosed with Severe Dysplasia(CIN3)involving ectocervical squamous mucosa and fragments of benign endocervical glandular epithelium. ?

Cervical Cancer: CIN3 is a high risk precursor to cervical cancer and needs to be treated and followed up. Local procedures like LEEP or cone biopsy are important to exclude possible occult invasion. Follow-up following those with visual exam, pap and HPV testing to exclude recurrence or residual are vital. Visual exam to exclude HPV disease of vagina or vulva are also important. ...Read more

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What is inverted papilloma with dysplasia and foci of in situto invasive squamous cell carcinoma(transitional)?

What is inverted papilloma with dysplasia and foci of in situto invasive squamous cell carcinoma(transitional)?

Location: What is the source of the biopsy? In the paranasal sinuses inverted papilloma is a sinus tumor traditionally treated with surgery, especially if there are foci of carcinoma. ...Read more

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Please translate. focal squamous atypia .. Ki-67 shows mild increase in cell proliferation. Focal VIN can't be excluded

Please translate.  focal squamous atypia .. Ki-67 shows mild increase in cell proliferation. Focal VIN can't be excluded

Pap smear: I take it that this is the result of a Pap smear and requires follow-up by your physician as this may show some abnormal cells that could be the precursor of a possible serious condition ...Read more

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Diagnosed with keratosis without dysplasia for white patch under tongue. Cancerous?

Diagnosed with keratosis without dysplasia for white patch under tongue. Cancerous?

No Cancer found: Your diagnosis is Keratosis(without Dysplasia). This means it is NOT a Cancer. But you should have this area checked by your doctor periodically, especially if you see any growth or change in this area. ...Read more

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Is hip dysplasia genetic?

Is hip dysplasia genetic?

Usually not: it may be caused by low amniotic fluid volume, inhibiting the fetal movement. I may be associated with rare bone displaces, or mor frequently seen in chromosomal disorders like Down syndrome. It may be a sporadic finding. ...Read more

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Mole grew back 6 weeks after shave. Report compound melanocytic nevus architectural disorder moderate cytologic atypia. What's this mean, melanoma ?

Mole grew back 6 weeks after shave. Report compound melanocytic nevus architectural disorder moderate cytologic atypia. What's this mean, melanoma ?

Seek 2nd opinion: Recurrence of a mole makes it likely that it is a melanoma. You should get further surgery done by a melanoma expert(surgical Oncologist). It always useful to seek 2 or 3 opinions and go with the aggregate of the recommendation, provided to you. ...Read more

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My skin biopsy says mild perivascular lymphcytic infiltrate. Mild mucopolysacharide like material in papilary dermis extending to skin. What is this?

My skin biopsy says mild perivascular lymphcytic infiltrate. Mild mucopolysacharide like material in papilary dermis extending to skin. What is this?

Nonspecific.: This is a very nonspecific picture. It can be seen in many common skin conditions, such as sunburn, eczema, and medication rashes. The fact that the pathologist did not list a diagnosis indicates that the appearance is too nonspecific to pinpoint a cause, so (s)he just described what (s)he saw. ...Read more