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Doctor insights on: Fibromatosis

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Is neurofibroma sarcoma genetic?

Is neurofibroma sarcoma genetic?

Yes: Neurofibromatosis type 1 and type 2 are both hereditary diseases. Malignant tumors like sarcomas are a rare complication of neurofibromatosis. The technical name given to these are "malignant peripheral nerve sheath tumors, " and these are a type of sarcoma. Here's a link to a free full text article on the subject: http://theoncologist.Alphamedpress.Org/content/5/6/477.Full. ...Read more

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Is malignant histiocytoma hereditary?

Is malignant histiocytoma hereditary?

MFH: Malignant fibrous histiocytoma is an umbrella term used to describe a range of more specific sarcomas. Although many of these tumors have unique cytogenetic profiles, they are largely not hereditary. ...Read more

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Is neurofibromatosis a cancer?

Is neurofibromatosis a cancer?

NO: Nf is a genetic disosrder that can predispose patient to tumors, mostly benign such as neurofibromas tumors of skin and other tissues .Plexiform neurofibromas are deeper tumors that affect nerves. These rarely become malignant. Other tumors can involve optic nerve (gliomas) , acoustic nerves (neuromas), meningiomas, astrocytoma brain, intestinal tumors (carcinoids)and adrenal pheochromocytomas. ...Read more

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What exactly is melanosis cutaneous fibromatosis?

What exactly is melanosis cutaneous fibromatosis?

Disease: Depends where the lesion is. Likely it is a benign tumor (fibroma) that has skin color changes (melanosis) that need to be followed and biopsied on a regular basis. Autoimmune disease might also be a contributing factor. Ur dermatologist could best answer this. ...Read more

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Is synovial chondrofibromatosis treated by radiation?

Is synovial chondrofibromatosis treated by radiation?

Synovial Disorders: Synovial chondromatosis, which is a proliferative disease of the synovium, results in multiple intra-articular loose bodies. This condition is typically treated surgically with open or arthroscopic synovectomy and/or loose body removal. See your local orthopaedic surgeon for treatment of this condition. ...Read more

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Is fibromatosis a soft tissue sarcoma?

Is fibromatosis a soft tissue sarcoma?

Yes: Fibromatosis, while it doesn't have "sarcoma"in the name is actually a low-grade sarcoma. However, this only applies to cases occurring in the abdomen. Less commonly, these tumors can occur on the extremity. Cases of Palmar and Plantar fibromatosis are not aggressive and generally behave in a benign fashion. Have your sarcoma pathology checked by an expert david.stockman@orthopath.com ...Read more

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What are types of neurofibromatosis besides acoustic neurofibromatosis?

What are types of neurofibromatosis besides acoustic neurofibromatosis?

3 major types: (nf 1 consists of two or more neurofibromas on or under the skin, or one plexiform neurofibroma, café au lait spots (pigmented, light brown macules, freckles of armpit and groin, lisch nodules (hamartomas of iris), optic nerve gliomas and skeletal deformities. Nf2 centrla nf with bilateral acoustic neuromas(balance, hearing, ringing ears) .Nf3 schwannomas develop cranial, spinal and peripheral nerves. ...Read more

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Is neurofibromatosis a rare disease?

Is neurofibromatosis a rare disease?

Define rare: At 1/4000 births this is relatively common compared to many genetically influenced afflictions. About a 3rd are new mutations and the others are passed from an affected parent to half their offspring. ...Read more

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What is kaposi hemangioendothelioma lymphomatosis?

What is kaposi hemangioendothelioma lymphomatosis?

Chronic skin tumor: Kaposi sarcoma is a hemangio endothelial sarcoma, reddish and nodular on the skin of the lower extremity, chronic in behavior and taking years to advance. Local excision and RT control it. With HIV, an acute variant found usually on the face and virtually fatal until found to be due to immunodeficiency and Herpes 8. When immune system regulated and Herpes 8 vaccine employed the disease regresses ...Read more

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Is hallux rigidus hereditary?

Is hallux rigidus hereditary?

In part. : Hallux rigidus is not clearly hereditary but there is probably some component that predisposes some to this problem. However, the major determinants are previous trauma to the joint and repetitive injury that accumulates over time. ...Read more

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Plantar fibromatosis does physical therapy help?

Plantar fibromatosis does physical therapy help?

Not usually: These growths can be treated with topical verapamil or removed surgically by a podiatrist. ...Read more

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How is familial adenomatous polyposis inherited?

How is familial adenomatous polyposis inherited?

Autosomal dominant: Enter omim in your browser and go to the database of all inherited diseases. Autosomal dominant means that affected individuals have one normal and one abnormal gene copy, the abnormal one dominating to cause disease. An affected person has a 50% chance to pass on the abnormal gene and fap with each pregnancy. ...Read more

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How is familial adenomatous polyposis inherited?

How is familial adenomatous polyposis inherited?

Autosomal Dominant: Fap is inherited in an autosomal dominant fashion. This means that if one parent has the gene, and the other parent doesn't, each child has a 50% chance of receiving the gene for fap. The disease causes hundreds of polyps to form in the colon (see the picture), leading to colon cancer. ...Read more

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What causes dysplastic nevi syndrome?

What causes dysplastic nevi syndrome?

It is a familial: condition, but a lot is still not understood about transfer in families. Patients with this syndrome are at higher risk for abnormal moles and melanoma. So regular checks with dermatology is imperative ...Read more

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Can peyronies disease cause dupuytrens contractures?

Can peyronies disease cause dupuytrens contractures?

Dupuytrens, Peyronie: and Ledderhose are all fibromatosis of the fascial layer. They are related but one does not cause the other. If one has a significant amount of genes for the trait then those that have locations outside the hand and have knuckle pads have a usually more aggressive the in the hand. WRT to your real question NO one can't transfer it by contact from one body area to another or to another person . ...Read more

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What is hereditary non-polyposis colorectal cancer (hnpcc) vs familial adenomatous polyposis (fap)?

What is hereditary non-polyposis colorectal cancer (hnpcc) vs familial adenomatous polyposis (fap)?

Both inherited: In fap presents as colonic polyps ( gardners syn will have other tumors ) , autosomal recessive due to mutations in gate keeper, tumor suppres gene. On the contrary hnpcc or lynch syndrome. Is autosomal dominant, due to dna mismatch in repair, associated with other cancers of stomach, endomet. Ca, ovary, brain, skin etc. ...Read more

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Is ectopic hamartomatous thymoma a benign or malignant tumor?

Is ectopic hamartomatous thymoma a benign or malignant tumor?

Depends: A thymoma is a malignant tumor of the thymus, and the seriousness depends on details in the pathology report. An ectopic thymus and a hamartoma are both benign, but if the report says "thymoma" then it is probably malignant although not necessarily very serious if completely removed. Discuss with your surgeon! ...Read more

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Are pelvic tumors, like malignant ovarian tumors, genetic?

To some extent: Almost all tumors have a genetic component in that heredity plays a role in the susceptibility to cancers. In the case of ovarian cancer there are a few well characterized genetic markers that portend higher incidence, e.g., brca 1 and brca 2. ...Read more

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Is potaba effective for plantar fibromas?

Is potaba effective for plantar fibromas?

Haven't heard of it: Potaba is potassium para-aminobenzoate, and has been used for scleroderma, for dupuytren's contractures, and for peyronie's disease of the penis. Potaba is believed to block the formation of abnormal fibrous tissue, but it is hard to find exact results about how well it works in the 3 preceding conditions. Unable to find any research / information on it's effectiveness for a plantar fibroma. ...Read more

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