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Doctor insights on: Fibrolamellar Carcinoma Of The Liver

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Is cirrhosis of the liver cancer?

Is cirrhosis of the liver cancer?

No, but raises risk: Cirrhosis describes the scarring that occurs when the liver has been damaged by hepatitis or alcohol use. Cirrhosis is not cancer, but it is a strong risk factor for the development of liver cancer. In fact, any person with cirrhosis should undergo regular screening to detect the development of cancer. Guidelines recommend a liver ultrasound every 6 months in patients with cirrhosis. ...Read more

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Dr. Barry Rosen
4,369 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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What is anaplastic metastic carcinoma of the liver?

What is anaplastic metastic carcinoma of the liver?

Poorly defined CA: Anaplastic is a pathology term to describe how the cells look under the microscope. It generally means theres no discernible pattern (generally not a good thing) metastatic means it has spread beyond its initial location. Liver means thats where it started. ...Read more

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Can liver transplant is possible in the fourth stage of liver cancer?

Can liver transplant is possible in the fourth stage of liver cancer?

May be: Depends on type of cancer, location, size and number of lesions. If stage 4 is from another site ( like colon cancer) then transplant is not an option. U need to discuss with ur oncologist. ...Read more

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Dr. Bryan Wu Dr. Wu
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What's the chromosome number of infiltrating ductal carcinoma?

Dr. Bryan Wu Dr. Wu
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What's the chromosome number of infiltrating ductal carcinoma?

Depends on grade: The level of chromosomal aberrations in infiltrating ductal carcinoma is correlated with the grade of the cancer cells. "grade" means the microscopic appearance and corresponds with how closely the cancer cells try to form normal breast structures. High grade or poorly differentiated infiltrating ductal carcinomas tend to have more chromosomal abnormalities than non-high grade carcinomas. ...Read more

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Malignant neoplasm of the breast which spread to the lung. The lung cancer is what type?

Malignant neoplasm of the breast which spread to the lung. The lung cancer is what type?

Same: With metastasis the distant lesion usually is the same histology -pathology as the primary. So breast adenocarcinomas will be the cell type in the chest- lung in the case cited. ...Read more

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What is the pathophysiology of liver cancer?

What is the pathophysiology of liver cancer?

Many: Hepatitis infection and chronic inflammation are some of the etiological factors--fibrosis and inflammation from chemicals has also been implicated. ...Read more

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Is macroglobular steatosis a form of liver cancer?

Is macroglobular steatosis a form of liver cancer?

No: Steatosis is accumulation of fat, macrogloular means large size globules. ...Read more

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Which is the survival of malignant pleural mesothelioma?

Which is the survival of malignant pleural mesothelioma?

Weeks to months: Malignant pleural mesothelioma usually presents with symptoms, such as chest pain, shortness of breath, etc. As such, it is usually found in an advanced stage, with little to be done as far as curative procedures. Treatment is generally symptomatic only. ...Read more

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What are the risk in second stage of liver cancer?

What are the risk in second stage of liver cancer?

Progression : Sounds like you are using the tnm classification for liver cancer staging. The risk is progression, worsening liver failure and death. Liver transplant is the only way to survive. Prognosis & survival can be prolonged by minimally invasive interventional radiology procedures - chemo-embolization, radio-embolization, & thermal-ablation. These can also be done as a bridge to liver transplantation! ...Read more

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Is liver cancer the final stage of life?

Is liver cancer the final stage of life?

Not necessarily: Liver cancer is a pretty bad diagnosis, depends whether it is primary or metastatic. There is treatment though including transplant if you are young and in good shape, and there are many other novel treatments as well. You need close follow up with your doctors at this point and to evaluate all the options. Good luck! ...Read more

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What are the causes of liver cirrhosis and liver cancer?

What are the causes of liver cirrhosis and liver cancer?

Etoh, hepatitis, etc: Alcohol and hepatitis c are the most common causes of cirrhosis in the us. Worldwide, hepatitis b is #1 etiology. Other causes include toxins, heart failure, inflammatory autoimmune diseases, or unknown causes in about 30% of cases (idiopathic). Hepatocellular cancer (primary liver ca) can occur in long standing cirrhosis from any cause but more so in a background of hepatitis b or c infection. ...Read more

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What are the symptoms of hepatocellular carcinoma?

What are the symptoms of hepatocellular carcinoma?

Often asymptomatic: Since the liver is so resilient, hcc can be asymptomatic until late stages. When symptoms are present they will manifest as nausea, taste disturbances, fatigue and sometimes jaundice. ...Read more

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Which form of lung cancer has the best prognosis?

Which form of lung cancer has the best prognosis?

Bronchoalveolar has: The least tendency to metastasize (travel), but tantalizes surrgeons because it seems cured, and can pop up later. It has the best prognosis for surviving for 5 years, but it's because it commonly grows slowly not becuase doctors' interventions produce the desired effect. Also, new biologic markers (egfr) and mutations may indicate response to drugs. ...Read more

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Is metastatic thyroid cancer of the lungs cureable?

Is metastatic thyroid cancer of the lungs cureable?

Most likely not: Thyroid cancer that has spreaded to the lung is unlikely to be curable. However, there are treatments available to control the disease such as radioactive iodine if the cancer cells would pick up iodine. Patient can be treated and maintained with good quality life for many many years with repeat treatment if necessary. ...Read more

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Is metastatic melanoma cancer of the lungs usually terminal or survivable?

Varies: This depends if the metastatic disease can be removed surgically. The best chance at survival depends on removal of all the disease. ...Read more

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What is the difference between liver cancer and cirrhosis of the liver?

What is the difference between liver cancer and cirrhosis of the liver?

Depends: Liver cancer can arise from cirrhosis which is called a primary liver cancer or hepatocellular cancer (HCC), or a secondary liver cancer meaning the cancer has come from somewhere else in the body (metastatic liver cancer). Either way, you need to see a liver specialist who can suggest options. ...Read more

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What is the average lifespan of hepatocellular carcinoma?

What is the average lifespan of hepatocellular carcinoma?

Complicated: The answer depends on several factors including the underlying liver disease, the size number and pattern of spread within the liver, and any other medical problems that the patient has that will effect their ability to tolerate therapy. There are several treatments available for hcc. ...Read more

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How risky is squamous cell carcinoma of the tonsil?

How risky is squamous cell carcinoma of the tonsil?

Depends: Early stage tonsil cancer due to hpv has a relatively good prognosis. Advanced cancer due to smoking, and alcohol has worse outcome. See this site for more information on oral cancers. http://www.cancer.gov/cancertopics/pdq/treatment/oropharyngeal/healthprofessional. ...Read more

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Tell me more about fibrolamellar hepatocellular carcinoma - a rare form of liver cancer?

Tell me more about fibrolamellar hepatocellular carcinoma - a rare form of liver cancer?

Better prognosis: Fibrolamellar hepatocellular carcinoma has better prognosis than usual liver cancers. The diagnosis is made by examining the tissue by a pathologist. See this site for more info. http://www.ncbi.nlm.nih.gov/pubmed/16475212. ...Read more

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What is anaplastic metastic carcinoma of the liver?

Poorly defined CA: Anaplastic is a pathology term to describe how the cells look under the microscope. It generally means theres no discernible pattern (generally not a good thing) metastatic means it has spread beyond its initial location. Liver means thats where it started. ...Read more

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Is there anything that causes high grade neuroendocrine carcinoma of the liver?

Is there anything that causes high grade neuroendocrine carcinoma of the liver?

Not known: Neuroendocrine carcinomas that originate in the liver are very rare ( about 200 reported cases in english literature). Intestinal neuroendocrine carcinomas that metastasize to the liver are more common, but still rare compared to the usual adult tumors. We do not know what causes any of these tumors. ...Read more

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Metastic liver carcinoma ?

Metastic liver carcinoma ?

Possible: It is possible for a cancer in the liver to spread to other organs. It is also common for other cancers to spread to the liver. The best examples being colorectal or lung cancers. Hope that helps. ...Read more

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High grade neuroendocrine carcinoma of liver?

High grade neuroendocrine carcinoma of liver?

There are treatments: The vast majority of neuroendocrine carcinomas in the liver originate in another site. Since the liver disease is the most common contributor to survival, we will often use liver directed therapies to control the liver component of the disease. There is an imaging techinque (ga68) used in europe that is available in certain centers in the us that can help evaluate the ds and response to trtment. ...Read more

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Is it true that hepatocellular carcinoma liver disease or liver cancer?

Liver cancer: Heaptocellular carcinoma is a primary cancer of the liver. Hcc is most commonly associated with underlying liver disease, such as viral hepatitis, but can be associated with other conditions of the liver that cause scarring or cirrhosis. Although hcc can also occur in otherwise normal liver substance, this is rare (only 10% of cases). ...Read more

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Can you tell me about liver cancer (hepatocellular carcinoma) and used nexavar (sorafenib)?

Can you tell me about liver cancer (hepatocellular carcinoma) and used nexavar (sorafenib)?

Used for Stage 4: Nexavar, or sorafenib, is used to treat advanced, unresectable hepatocellular carcinoma. It is also used to treat patients with advanced kidney cancer. This drug is a multikinase inhibitor and works by decreasing tumor growth and replication, by inhibiting the formation of blood vessels that tumors rely on to get nourishment. This is not a curative treatment, prolonging survival on average 7 mo. ...Read more

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I found a large tumor on my right liver. After cutting the entire right liver off, doctor found that it is actually adrenocortical carcinoma. Pls help?

I found a large tumor on my right liver. After cutting the entire right liver off, doctor found that it is actually adrenocortical carcinoma. Pls help?

Sorry to hear: It is hard to give recommendations since we do not know all the information pertaining your case. Two things i would suggest: first, make sure your doc has expertise in management of these rare cancers. I personally refer them to an academic center. Second, you should get genetic testing for lifraumeini (p53 mutation), especially if there's family history of cancer. Best to you and god bless. ...Read more

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Iam 63 old have soft tisse mass in descedig colon measres 67*42*38 mm with focal liver lesion in rt lobe show adeno carcinoma with necrosis?

Iam 63 old have soft tisse  mass  in descedig colon measres 67*42*38 mm  with focal liver lesion in rt lobe 
show adeno carcinoma  with necrosis?

Colon mass: Cheryl, this is difficult to answer. If you have a biopsy diagnosis of colorectal carcinoma, then the liver lesion may represent a metastasis. It could also represent only a liver hemangioma. Only a liver biopsy of the lesion is definitive. Red cell tagging studies sometimes can be definitive noninvasive study for liver hemangioma but does not have 100% sensitivity and may give false negative. ...Read more

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Carcinoma endometrium spread to lungs,liver,lymphnod,bone.2nd line chemo goin on.pain not tolerable.will chemo will be effective?how to manage pain.

Carcinoma endometrium spread to lungs,liver,lymphnod,bone.2nd line chemo goin on.pain not tolerable.will chemo will be effective?how to manage pain.

Specialty referral: This is a question that needs to be addressed without delay by your multidiciplinary team. Both the pain management people and perhaps the radiation oncologist who can manage local bone pain ("spot-welding") may have something to offer. Most such pain can be handled with opiates when the "war on drugs" doesn't interfere. You have my sympathy. Best wishes. ...Read more

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What is the best treatment for hepatocellular carcinoma besides liver transplantation?

What is the best treatment for hepatocellular carcinoma besides liver transplantation?

Resection: Licer resection is the next best treatment, tumor ablation would be next followed up by liver directed chemotherapy and finally systemic (total body) chemotherapy. ...Read more

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What does it mean to be diagnosed with carcinoma head of pancreas with liver metastasis (stage iv) how fatal is this disease?

What does it mean to be diagnosed with carcinoma head of pancreas with liver metastasis (stage iv) how fatal is this disease?

It is very bad News: Pancreatic Cancer is the most dangerous and difficult to treat Cancer there is. Yet there is some treatment available and it is getting slowly better each year. Right now it is a matter of trying to control and extend life by a few months if we are lucky. Treatment is mostly done using chemotherapy drugs for cases like this one who have spread (Metastatic). ...Read more

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What is small cell carcinoma lung cancer with liver cancer stage 4?

Bad situation: Small cell is a very bad cancer. Stage four is very advanced. Very poor prognosis at best-- usually months only. ...Read more

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Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more

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My mother has been diagnosed with a squamous cell rectal carcinoma with metastatic liver and lung tumors how long with treatment should we elect to?

My mother has been diagnosed with a squamous cell rectal carcinoma with metastatic liver and lung tumors how long with treatment should we elect to?

Probably anal cancer: Likely anal and not rectal given the pathology. If squamous cell, needs specific chemotherapy. However, not curable but treatable. Treatment should be continued based on response, however, the drugs used for this cancer have a cumulative toxicity. Hope this helps. ...Read more

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Dr. Lawrence Kessler
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Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more