Doctor insights on:
Fibrinogen Storage Disease
Is a fibrinogen result of 11.2 nmol/l (reference values 5.3-10.3 nmol/l) worrisome for someone with heart disease?
Doubt it: Fibrinogen is a protein that is involved in clot formation. It is important to know why someone ordered fibrinogen levels in your case. Things that can increase levels of Fibrinogen go from: - Inflammatory process, fevers, recent flu for example - Even Stress (Merry XMAS) - Smoking If you smoke (quit) if you smoke and are on OCP STOP. Otherwise, healthy lifestyle will take care of it ;) ...Read moreSee 1 more doctor answer
A genetic disease is a disease that is caused by a defect in the genetic (dna) material in a gene(s). It can be inherited and mosy pose a risk to other family members and/or to future children. For many genetic diseases there are molecular tests that allow detection of a change(s) called mutations, we can also detect deltions or other changes to the gene's dna that can also result ...Read more
No, see below: Hyper-clotting disorders can be inherited or acquired. Common tests for inherited hyper-clotting diseases include testing for antithrombin, protein C and S deficiencies, factor V leiden and prothrombin gene mutations. For acquired ones, tests may include antiphopholipid syndrome, myeloproliferative, PNH, etc. Fibrinogen is reactive and dysfibrinogenemia is rare for thrombosis, thus not included. ...Read more
Is a simple coagulation lab test (PT/PTT INR & Fibrinogen) sufficient to diagnose Protein C,
&/or Factor V leidmen mutation disorders?
Fibrinogen: Is a key element of the clotting cascade. It is the precursor to fibrin. The conversion is activated by thrombin. ...Read more
My fibrinogen level is 5.4 cut of 4.7 is this dangerous my appt is also increased 45.2 cut of 36.5 really scared ?
Circulating Anticoag: If you meant aPTT, you may have what's called a circulating amici agility. Do not be scared. Ask questions, see a hematologist for further testing. Most times, aspirin daily is all you need. Please seek all the information you can get. Until you have answers, DO NOT GET PREGNANT, and maybe take a baby aspirin daily until further advised by your doctors ...Read more
Estrogen/fibrinogen: It depends on the route of administration. Typically, estrogen raises fibrinogen levels in the body (this is one of the many reasons why women taking birth control pills and hormone replacement therapy are more susceptible to blood clots). There are a few reports however that transdermal estrogen lowers fibrinogen levels. ...Read more
Multiple reasons.: There are multiple possible causes of low fibrinogen levels including: end-stage liver disease, severe malnutrition, congenital afibrinogenemia or hypofibrinogenemia, severe infections resulting in consumption of fibrinogen, medications that may impair hepatic synthetic function including valproic acid or l--asparaginase. ...Read moreSee 1 more doctor answer
Any tissue injury is associated with elevation in fibrinogen. Most clinically evident tumors have areas of necrosis and that can be a trigger for elevation of fibrinogen.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex, if you have sex. ...Read more
Clotting proteins: D-dimer is a breakdown product of fibrin that has been crosslinked, thus in elevated levels it indicates active clot lysis. Fibrinogen is a clotting factor normally present in the blood and needed to make fibrin, an essential part of a clot. In some settings, fibrinogen will go up in response to inflammatory or other stimuli. ...Read more
Eliquis: There should be no meaningful changeGet a more detailed answer ›
Yes: PRV is hypercoaguable conditionGet a more detailed answer ›
Interstitial lung disease is a group of various conditions that affect the thin tissue between the airspaces in the lung. These disorders lead to thickening, fibrosis & scarring of the lung over time, making it difficult for patients to breathe. They can be caused by exposure to environmental toxins, certain drugs, infections, autoimmune disorders, genetic problems ...Read more
Is a malignant condition that may have the appearance of eczema, with skin changes involving the nipple of the breast. The incidence is approximately around 3%. Most of them are also associated with underlying breast cancer. Biopsy should be done to confirm. Mammogram, sonogram and perhaps MRI breast should be done-depending on the case to ...Read more
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