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Doctor insights on: Fibrinogen Storage Disease

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Is a fibrinogen result of 11.2 nmol/l (reference values 5.3-10.3 nmol/l) worrisome for someone with heart disease?

Is a fibrinogen result of 11.2 nmol/l (reference values 5.3-10.3 nmol/l) worrisome for someone with heart disease?

Doubt it: Fibrinogen is a protein that is involved in clot formation. It is important to know why someone ordered fibrinogen levels in your case. Things that can increase levels of Fibrinogen go from: - Inflammatory process, fevers, recent flu for example - Even Stress (Merry XMAS) - Smoking If you smoke (quit) if you smoke and are on OCP STOP. Otherwise, healthy lifestyle will take care of it ;) ...Read more

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Dr. Richard Roberts
230 doctors shared insights

Genetic Disease (Definition)

A genetic disease is a disease that is caused by a defect in the genetic (dna) material in a gene(s). It can be inherited and mosy pose a risk to other family members and/or to future children. For many genetic diseases there are molecular tests that allow detection of a change(s) called mutations, we can also detect deltions or other changes to the gene's dna that can also result ...Read more


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Is PT and PTT enough to test for hyper-clotting disorder? Is fibrinogen needed?

Is PT and PTT enough to test for hyper-clotting disorder? Is fibrinogen needed?

No, see below: Hyper-clotting disorders can be inherited or acquired. Common tests for inherited hyper-clotting diseases include testing for antithrombin, protein C and S deficiencies, factor V leiden and prothrombin gene mutations. For acquired ones, tests may include antiphopholipid syndrome, myeloproliferative, PNH, etc. Fibrinogen is reactive and dysfibrinogenemia is rare for thrombosis, thus not included. ...Read more

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What is the effect of fibrinogen ?

What is the effect of fibrinogen ?

HEPARIN: Heparin is administered for several days to control dic, increase fibrinogen and platelets.Fibrinogen is the precursor of fibrin. ...Read more

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What is the definition or description of: fibrinogen?

Fibrinogen: Is a key element of the clotting cascade. It is the precursor to fibrin. The conversion is activated by thrombin. ...Read more

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My fibrinogen level is 5.4 cut of 4.7 is this dangerous my appt is also increased 45.2 cut of 36.5 really scared ?

My fibrinogen level is 5.4 cut of 4.7 is this dangerous my appt is also increased 45.2 cut of 36.5 really scared ?

Circulating Anticoag: If you meant aPTT, you may have what's called a circulating amici agility. Do not be scared. Ask questions, see a hematologist for further testing. Most times, aspirin daily is all you need. Please seek all the information you can get. Until you have answers, DO NOT GET PREGNANT, and maybe take a baby aspirin daily until further advised by your doctors ...Read more

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What is the effect of pregnancy on fibrinogen ?

What is the effect of pregnancy on fibrinogen ?

PREGNANCY: Certain conditions in pregnancy can cause dic, diagnosed by thrombocytopenia, increased PTT and pt, increased serum fibrin degradation products and decreased fibrinogen level. ...Read more

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What effect does estrogen have on fibrinogen ?

What effect does estrogen have on fibrinogen ?

Estrogen/fibrinogen: It depends on the route of administration. Typically, estrogen raises fibrinogen levels in the body (this is one of the many reasons why women taking birth control pills and hormone replacement therapy are more susceptible to blood clots). There are a few reports however that transdermal estrogen lowers fibrinogen levels. ...Read more

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What is the definition or description of: fibrinogen levels low?

Multiple reasons.: There are multiple possible causes of low fibrinogen levels including: end-stage liver disease, severe malnutrition, congenital afibrinogenemia or hypofibrinogenemia, severe infections resulting in consumption of fibrinogen, medications that may impair hepatic synthetic function including valproic acid or l--asparaginase. ...Read more

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Why do doctors order fibrinogen degredation product?

HEPARIN: Heparin is administered for several days to control dic, increase fibrinogen and platelets.Fibrinogen is the precursor of fibrin. ...Read more

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Why does fibrinogen tend to be higher in tumor patients?

Tissue injury: Any tissue injury is associated with elevation in fibrinogen. Most clinically evident tumors have areas of necrosis and that can be a trigger for elevation of fibrinogen.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex, if you have sex. ...Read more

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Could colitis cause high fibrinogen and clumped platelets?

Could colitis cause high fibrinogen and clumped platelets?

Yes: Ulcerative colitis is a chronic inflammatory condition, and as such, can increase platelet production and fibrinogen. However, seeing these elevations are not very specific to uc and can be present in any type of inflammation, including infection. ...Read more

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What is low d-dimer by high fibrinogen?

What is low d-dimer by high fibrinogen?

Clotting proteins: D-dimer is a breakdown product of fibrin that has been crosslinked, thus in elevated levels it indicates active clot lysis. Fibrinogen is a clotting factor normally present in the blood and needed to make fibrin, an essential part of a clot. In some settings, fibrinogen will go up in response to inflammatory or other stimuli. ...Read more

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Why doe the fibrinogen concentration increases in edema?

Why doe the fibrinogen concentration increases in edema?

Read this article: Restoration of compensation in persons with congestive heart failure usually associated with increase in blood viscosity. This change in viscosity will lead a significant increase in hematocrit and fibrinogen concentration. ...Read more

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Please answer! what does a low d-dimer by high fibrinogen mean?

Clots coming ; going: D-dimer is increased with breakdown of clots to crosslinked fibrin. Fibrinogen forms fibrin whose fibers become crosslinked to form a clot. So high fibrinogen infers clot formation, not breakdown, so d-dimer is inferred to be low. ...Read more

Dr. Matthew Majzun
20 doctors shared insights

Interstial Lung Disease (Definition)

Interstitial lung disease is a group of various conditions that affect the thin tissue between the airspaces in the lung. These disorders lead to thickening, fibrosis & scarring of the lung over time, making it difficult for patients to breathe. They can be caused by exposure to environmental toxins, certain drugs, infections, autoimmune disorders, genetic problems ...Read more


Dr. Ed Friedlander
16 doctors shared insights

Paget Disease Of The Nipple (Definition)

Is a malignant condition that may have the appearance of eczema, with skin changes involving the nipple of the breast. The incidence is approximately around 3%. Most of them are also associated with underlying breast cancer. Biopsy should be done to confirm. Mammogram, sonogram and perhaps MRI breast should be done-depending on the case to ...Read more