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Doctor insights on: Fibrinogen

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Dr. Raymond Migrino
390 Doctors shared insights

Fibrinogen (Overview)

Is a key element of the clotting cascade. It is the precursor to fibrin. The conversion is activated by thrombin.


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What is the effect of fibrinogen?

What is the effect of fibrinogen?

HEPARIN: Heparin is administered for several days to control dic, increase fibrinogen and platelets.Fibrinogen is the precursor of fibrin. ...Read more

Dr. Raymond Migrino
390 Doctors shared insights

Fibrinogen (Overview)

Is a key element of the clotting cascade. It is the precursor to fibrin. The conversion is activated by thrombin.


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Sn blood test results of 479 mg/dl fibrinogen a high level?

Sn blood test results of 479 mg/dl fibrinogen a high level?

Yes: The normal levels of fibrinogen range from about 150-400mg/dl. There are normal circumstances in which the level may be higher, e.g., pregnancy. Any lab value needs to be interpreted in the context of other health issues and this value may not be associated with a disease. Do consult the doctor who ordered the blood test. ...Read more

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Please answer! What does a low d-dimer by high fibrinogen mean?

Please answer! What does a low d-dimer by high fibrinogen mean?

Clots coming ; going: D-dimer is increased with breakdown of clots to crosslinked fibrin. Fibrinogen forms fibrin whose fibers become crosslinked to form a clot. So high fibrinogen infers clot formation, not breakdown, so d-dimer is inferred to be low. ...Read more

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What is the effect of fibrinogen?

HEPARIN: Heparin is administered for several days to control dic, increase fibrinogen and platelets.Fibrinogen is the precursor of fibrin. ...Read more

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What is the definition or description of: fibrinogen?

Fibrinogen: Is a key element of the clotting cascade. It is the precursor to fibrin. The conversion is activated by thrombin. ...Read more

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My fibrinogen level is currently 143, should I be concerned?

Symptoms?: Is there a particular reason why you had your fibrinogen checked? Have you had a bleeding symptoms? Do you have any other "abnormal" labs measuring the coagulation cascade? For most labs, the low normal range for fibrinogen is 150, so you are just below that. Without knowing more about your particular clinical situation, your level of fibrinogen is not worrisome. ...Read more

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My fibrinogen level is 5.4 cut of 4.7 is this dangerous my appt is also increased 45.2 cut of 36.5 really scared?

My fibrinogen level is 5.4 cut of 4.7 is this dangerous my appt is also increased 45.2 cut of 36.5 really scared?

Circulating Anticoag: If you meant aPTT, you may have what's called a circulating amici agility. Do not be scared. Ask questions, see a hematologist for further testing. Most times, aspirin daily is all you need. Please seek all the information you can get. Until you have answers, DO NOT GET PREGNANT, and maybe take a baby aspirin daily until further advised by your doctors ...Read more

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What effect does estrogen have on fibrinogen?

What effect does estrogen have on fibrinogen?

Estrogen/fibrinogen: It depends on the route of administration. Typically, estrogen raises fibrinogen levels in the body (this is one of the many reasons why women taking birth control pills and hormone replacement therapy are more susceptible to blood clots). There are a few reports however that transdermal estrogen lowers fibrinogen levels. ...Read more

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What is the definition or description of: fibrinogen levels low?

Multiple reasons.: There are multiple possible causes of low fibrinogen levels including: end-stage liver disease, severe malnutrition, congenital afibrinogenemia or hypofibrinogenemia, severe infections resulting in consumption of fibrinogen, medications that may impair hepatic synthetic function including valproic acid or l--asparaginase. ...Read more

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What is low d-dimer by high fibrinogen?

Clotting proteins: D-dimer is a breakdown product of fibrin that has been crosslinked, thus in elevated levels it indicates active clot lysis. Fibrinogen is a clotting factor normally present in the blood and needed to make fibrin, an essential part of a clot. In some settings, fibrinogen will go up in response to inflammatory or other stimuli. ...Read more

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Why do doctors order fibrinogen degredation product?

HEPARIN: Heparin is administered for several days to control dic, increase fibrinogen and platelets.Fibrinogen is the precursor of fibrin. ...Read more

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Why does fibrinogen tend to be higher in tumor patients?

Tissue injury: Any tissue injury is associated with elevation in fibrinogen. Most clinically evident tumors have areas of necrosis and that can be a trigger for elevation of fibrinogen.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex, if you have sex. ...Read more

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Why doe the fibrinogen concentration increases in edema?

Why doe the fibrinogen concentration increases in edema?

Read this article: Restoration of compensation in persons
with congestive heart failure usually associated
with increase in blood viscosity.
This change in viscosity will lead
a significant increase in hematocrit
and fibrinogen concentration. ...Read more

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Please answer! What does a low d-dimer by high fibrinogen mean?

Clots coming ; going: D-dimer is increased with breakdown of clots to crosslinked fibrin. Fibrinogen forms fibrin whose fibers become crosslinked to form a clot. So high fibrinogen infers clot formation, not breakdown, so d-dimer is inferred to be low. ...Read more

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I'm 41y female my fibrinogen is 431mg/dl what does it mean? What supplements can I take to lower it?

No need to treat: Your fibrinogen is mildly elevated and there is no need to try to reduce it. As it is, there no simple thing that you can take to reduce the level. ...Read more

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Really scared gp not concerned my fibrinogen derived was 5.4 with cormal rage below 4.7 my aptr was 45.2 normal under 36.5 should I be scared plzzz?

Big picture: Fibrinogen levels flucuate, are often high if you have significant inflammation, and a young woman's levels may rise at the same time each month. I suggest you recheck when in your usual state of health. If the activated partialntheomboplastin time is still up, get checked for anti phospholipid antibody and/or specific factor deficiencies as appropriate. ...Read more

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If I have <0.5g of fibrinogen per L of blood, am I more likely to bleed to death from a 1cm deep cut? Could I bleed to death from a long shallow cut?

If I have <0.5g of fibrinogen per L of blood, am I more likely to bleed to death from a 1cm deep cut? Could I bleed to death from a long shallow cut?

How do you FEEL?: If this is well below reference range, but you have not manifested any obvious bleeding tendency by age 16, it's time to get with the lab and figure what's going on with the assay. You may have a variant that's not measured by the test, or it may have been consumed on the way to the lab. You're not going to bleed out from trivial trauma. I suggest repeating using a different assay. ...Read more

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What is the effect of pregnancy on fibrinogen?

What is the effect of pregnancy on fibrinogen?

PREGNANCY: Certain conditions in pregnancy can cause dic, diagnosed by thrombocytopenia, increased PTT and pt, increased serum fibrin degradation products and decreased fibrinogen level. ...Read more

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Sn blood test results of 479 mg/dl fibrinogen a high level?

Yes: The normal levels of fibrinogen range from about 150-400mg/dl. There are normal circumstances in which the level may be higher, e.g., pregnancy. Any lab value needs to be interpreted in the context of other health issues and this value may not be associated with a disease. Do consult the doctor who ordered the blood test. ...Read more

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My father (68)had ishaemic stroke 10 days ago. His fibrinogen now is 900 (it must be 200-400). For how long will it be so high.?

Cause not effect: The high fibrinogen may well be the cause of the stroke rather than a result of the stroke and how long it lasts depends on why it is high. Hope he's doing well. ...Read more

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My plasma fibrinogen is less than 0.5g/L which is really low. Mum has dysfibrinogenaemia but I'm wondering if low fibrinogen can be caused by cancer?

My plasma fibrinogen is less than 0.5g/L which is really low. Mum has dysfibrinogenaemia but I'm wondering if low fibrinogen can be caused by cancer?

No: Cancer does not cause low plasma fibrinogen. It would be good idea to see a doctor for a complete evaluation.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex.
Get HPV vaccine. ...Read more

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Could colitis cause high fibrinogen and clumped platelets?

Could colitis cause high fibrinogen and clumped platelets?

Yes: Ulcerative colitis is a chronic inflammatory condition, and as such, can increase platelet production and fibrinogen. However, seeing these elevations are not very specific to uc and can be present in any type of inflammation, including infection. ...Read more

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If fibrinogen was 5.4. cut off 4.7 does this mean il get a blood clot?

No: Fibrinogen is an acute phase reactant and rises when you get sick from any of a variety of causes. Further, longstanding hyperfibrinogenemia isn't even really a risk factor for thrombosis in the first place, though a few mutated forms of other clotting factors are. Best wishes. ...Read more