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Doctor insights on: Fibrinogen

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Dr. Raymond Migrino
388 Doctors shared insights

Fibrinogen (Overview)

Is a key element of the clotting cascade. It is the precursor to fibrin. The conversion is activated by thrombin.


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What is the effect of fibrinogen?

What is the effect of fibrinogen?

HEPARIN: Heparin is administered for several days to control dic, increase fibrinogen and platelets.Fibrinogen is the precursor of fibrin.

Dr. Raymond Migrino
388 Doctors shared insights

Fibrinogen (Overview)

Is a key element of the clotting cascade. It is the precursor to fibrin. The conversion is activated by thrombin.


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Sn blood test results of 479 mg/dl fibrinogen a high level?

Sn blood test results of 479 mg/dl fibrinogen a high level?

Yes: The normal levels of fibrinogen range from about 150-400mg/dl. There are normal circumstances in which the level may be higher, e.g., pregnancy. Any lab value needs to be interpreted in the context of other health issues and this value may not be associated with a disease. Do consult the doctor who ordered the blood test.

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Please answer! What does a low d-dimer by high fibrinogen mean?

Please answer! What does a low d-dimer by high fibrinogen mean?

Clots coming ; going: D-dimer is increased with breakdown of clots to crosslinked fibrin. Fibrinogen forms fibrin whose fibers become crosslinked to form a clot. So high fibrinogen infers clot formation, not breakdown, so d-dimer is inferred to be low.

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What is the effect of fibrinogen?

HEPARIN: Heparin is administered for several days to control dic, increase fibrinogen and platelets.Fibrinogen is the precursor of fibrin.

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What is the definition or description of: fibrinogen?

Fibrinogen: Is a key element of the clotting cascade. It is the precursor to fibrin. The conversion is activated by thrombin.

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My fibrinogen level is currently 143, should I be concerned?

Symptoms?: Is there a particular reason why you had your fibrinogen checked? Have you had a bleeding symptoms? Do you have any other "abnormal" labs measuring the coagulation cascade? For most labs, the low normal range for fibrinogen is 150, so you are just below that. Without knowing more about your particular clinical situation, your level of fibrinogen is not worrisome.

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My fibrinogen level is 5.4 cut of 4.7 is this dangerous my appt is also increased 45.2 cut of 36.5 really scared?

My fibrinogen level is 5.4 cut of 4.7 is this dangerous my appt is also increased 45.2 cut of 36.5 really scared?

Circulating Anticoag: If you meant aPTT, you may have what's called a circulating amici agility. Do not be scared. Ask questions, see a hematologist for further testing. Most times, aspirin daily is all you need. Please seek all the information you can get. Until you have answers, DO NOT GET PREGNANT, and maybe take a baby aspirin daily until further advised by your doctors

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What effect does estrogen have on fibrinogen?

What effect does estrogen have on fibrinogen?

Estrogen/fibrinogen: It depends on the route of administration. Typically, estrogen raises fibrinogen levels in the body (this is one of the many reasons why women taking birth control pills and hormone replacement therapy are more susceptible to blood clots). There are a few reports however that transdermal estrogen lowers fibrinogen levels.

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What is the definition or description of: fibrinogen levels low?

Multiple reasons.: There are multiple possible causes of low fibrinogen levels including: end-stage liver disease, severe malnutrition, congenital afibrinogenemia or hypofibrinogenemia, severe infections resulting in consumption of fibrinogen, medications that may impair hepatic synthetic function including valproic acid or l--asparaginase.

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What is low d-dimer by high fibrinogen?

Clotting proteins: D-dimer is a breakdown product of fibrin that has been crosslinked, thus in elevated levels it indicates active clot lysis. Fibrinogen is a clotting factor normally present in the blood and needed to make fibrin, an essential part of a clot. In some settings, fibrinogen will go up in response to inflammatory or other stimuli.

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Why do doctors order fibrinogen degredation product?

HEPARIN: Heparin is administered for several days to control dic, increase fibrinogen and platelets.Fibrinogen is the precursor of fibrin.

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Why does fibrinogen tend to be higher in tumor patients?

Tissue injury: Any tissue injury is associated with elevation in fibrinogen. Most clinically evident tumors have areas of necrosis and that can be a trigger for elevation of fibrinogen.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex, if you have sex.

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Why doe the fibrinogen concentration increases in edema?

Why doe the fibrinogen concentration increases in edema?

Read this article: Restoration of compensation in persons with congestive heart failure usually associated with increase in blood viscosity. This change in viscosity will lead a significant increase in hematocrit and fibrinogen concentration.

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Please answer! What does a low d-dimer by high fibrinogen mean?

Clots coming ; going: D-dimer is increased with breakdown of clots to crosslinked fibrin. Fibrinogen forms fibrin whose fibers become crosslinked to form a clot. So high fibrinogen infers clot formation, not breakdown, so d-dimer is inferred to be low.

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I'm 41y female my fibrinogen is 431mg/dl what does it mean? What supplements can I take to lower it?

No need to treat: Your fibrinogen is mildly elevated and there is no need to try to reduce it. As it is, there no simple thing that you can take to reduce the level.