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Doctor insights on: Fetus Disease Immunosuppressive Cyclosporine

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Can my fetus be more susceptible to infection or disease if I am taking an immunosuppressive like cyclosporine?

Can my fetus be more susceptible to infection or disease if I am taking an immunosuppressive like cyclosporine?

No: Very minimal amounts of Cyclosporine actually cross the placenta. Your baby should not be at any increased risk of infection. There have been reports of an increased risk of preterm delivery and smaller babies. Some of that may be related to whatever condition the woman was on Cyclosporine for. ...Read more

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Dr. William Singer
33 doctors shared insights

Sandimmune (Definition)

Sandimmune is an immune system suppressor which is a kind of ...Read more


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My husband is taking cyclosporine/immunosuppressive medicine long-term, could that cause birth deffects on a fetus/baby?

My husband is taking cyclosporine/immunosuppressive medicine long-term, could that cause birth deffects on a fetus/baby?

Tough question.: Although the FDA had classified cyclosporin as pregnancy category C meaning that the risk to the fetus is unknown, its effect on sperm is even less known. Thus it is a subject you will need to discuss with the OB doctor. ...Read more

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Can you use cyclosporine chronic use?

Can you use cyclosporine chronic use?

Needs monitoring: Cyclosporine is a calcineurin inhibitor and it has a narrow therapeutic index. If the blood level of cyclosporine is too high, it is likely to cause adverse effects which include nephrotoxicity, hyperlipidemia, gingival hyperplasia, and hair growth. Whether it is used as an anti-rejection agent or as an immunosuppressant in treating auto-immune diseases, one needs to have a close follow-up. ...Read more

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Treat psoriasis with cyclosporine?

Treat psoriasis with cyclosporine?

Last resort: Cyclosporine is an effective treatment for psoriasis - but it is usually used only when all else has failed, because it is toxic to the liver and kidneys, among other things, and weakens the immune system. It should never be taken without close monitoring by an expert in its use for that purpose (usually a dermatologist). ...Read more

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Is there a web site for free cyclosporine?

Is there a web site for free cyclosporine?

RxAssist Database: Talk to your physician about your drug costs. And, don't be reluctant to look at all possibilities for reducing your medication costs-including those from drug companies, community health centers, local social service programs or charitable programs. Visit www.Rxassist.Org to help find options. ...Read more

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Is there a web site for cyclosporine medication?

Is there a web site for cyclosporine medication?

No: Cyclosporine is a prescription. You can't get it just going online. You need a doctor's prescription for it after being evaluated. ...Read more

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Does cyclosporine work on hives?

Yes.: Cyclosporine and other potent immunosuppressant agents are very effective for hives. They are reserved for patients whose hives are resistant to medications with fewer side-effects and that require less on-going monitoring for safety. ...Read more

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How does cyclosporine damage kidneys ?

How does cyclosporine damage kidneys ?

Different ways: While Cyclosporine is a very important medication used in the transplant field and in different rheumatologic and autoimmune diseases it sometimes may damage the kidneys by causing constriction of the vessels inside them. If you are concerned about potential side effects of this medication you should ask your prescribing physician about it. ...Read more

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Does cyclosporine work for hives at all?

Does cyclosporine work for hives at all?

Yes: Cyclosporine is a "second line" medication for hives. It is useful for chronic hives in people who will need long-term treatment, and has more side effects than the "first line" treatments such as antihistamines. It is only used when first line medications don't work - that is, when the benefits of the drug outweigh its risks. ...Read more

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Cyclosporine for immunotherapy and other uses. Safe?

Relatively, yes: All drugs have potential side effects, some worse than others. Cyclosporine works well for its uses, but patients must be willing to work with doc closely to prevent untoward events, e.g. Reporting any side effects, reporting fever or infection immediately no matter how seemingly slight. Co-operate with doc when monitoring lab work is asked for; it's for your protection & well-being. ...Read more

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Has anyone ever been given cyclosporine to treat eczema?

Severe cases.: In very severe cases Cyclosporine has been used. In most cases it is treated with prescription creams and oral steroids for brief periods. A recent report shows that vitamin d 1600 units is helpful for eczema. In over 60 per cent of eczema patient sublingual desentization can cause resolution of eczema over a 2 year period. ...Read more

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Whats the difference between methotrexate and cyclosporine?

Whats the difference between methotrexate and cyclosporine?

While both used ....: For gvhd prophylaxis, they are completely different drugs with distinct mechanisms of action. Methotrexate is a dihydrofolate reductase inhibitor that inhibits 1-carbon metabolism needed to make nucleotides. Csa binds cyclophillin to block an intracellular phosphatase (pp2a), and in so doing, blocks nuclear translocation of nfat (a transcription factor), preventing il2 synthesis and immune fxn. ...Read more

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Is taking 1.5mg of cyclosporine daily for long periods safe?

Is taking 1.5mg of cyclosporine daily for long periods safe?

No: However, safe is a relative question, when this medication is used. Usually, Cyclosporine is used to suppress rejection in transplants. It can also be used for severe autoimmune problems. Therefore, the safety is felt to be greater than the danger without it. But it can cause convulsions, peptic ulcers, pancreatitis, fever, vomiting, diarrhea, confusion, liver and kidney failure. ...Read more

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Can someone take cyclosporine at low does for long periods relatively safely?

See below: It is possible so long as you do not develop kidney weakness or hypertension. ...Read more

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I have to take sandimmun neoral (cyclosporine)for 4 month.How long I have to wait after i stop to take the medicine if i want to drink a lot of alcol?

Wrong question!!!: Binge drinking or "drinking a lot of alcohol" is not suggested. Studies have shown that even one episode of binge drinking in the younger individual can cause long-term neurophysiological changes. ...Read more

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Is there a treatment of psoriasis with cyclosporine?

Is there a treatment of psoriasis with cyclosporine?

Yes: Cyclosporin is a systemic medications used for severe psoriasis. It works quickly, but is toxic to the kidneys with long term use, so it is recommended that it be used for a limited period of time (6-12 months maximum). Generally it is used to get a patient through a short-term severe flare or to give rapid response while waiting for a slower acting medication like Methotrexate to "kick in". ...Read more

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What are cyclosporine eye drops?

Restasis: Restasis is the brand-name for Cyclosporine drops. This is the only known medication that increases tear production. It is available by prescription only, and is fairly expensive. ...Read more

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Dr. Wendy Askew
39 doctors shared insights

Neoral (Definition)

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