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Doctor insights on: Fertility Hereditary

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Is infertility hereditary?

Is infertility hereditary?

Possibly: Some forms of infertility are hereditary. For instance some forms of male infertility have genetic components that are automatically passed to male children (y chromosome microdeletions). Endometriosis definitely has a hereditary component. Pcos also runs in families. And fragile x which can affect egg production is hereditary as well. The vast majority of time infertility is not hereditary. ...Read more

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Dr. Khurram Rehman
1,639 doctors shared insights

Fertility (Definition)

Fertility refers to the ability of a woman to conceive a child, or to the ability of a man to ...Read more


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Can alcoholism affect male fertility?

Can alcoholism affect male fertility?

Yes: Alcohol use in men may have negative effects on sperm (decreased semen volume, movement, shape, and count), with inflammation and increased white blood cells in the semen. Alcohol intake is associated with lower levels of fuel (gonadotropins) from the brain and direct effects on the testes leading to lower testosterone. Interestingly, a specific component of red wine, myricetin may affect sperm. ...Read more

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Who should undergo genetic counseling for hereditary non-polyposis colorectal cancer (hnpcc)?

Who should undergo genetic counseling for hereditary non-polyposis colorectal cancer (hnpcc)?

Family history: There are a number of different inherited defects that cause hnpcc. A person with strong family history of colon cancer, occurring at a young age should seek counseling. ...Read more

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What genes cause hereditary ovarian cancer?

What genes cause hereditary ovarian cancer?

BRCA 1 and 2: The breast-ovarian cancer (brca 1 and 2) genes are the only ones so far proven to cause susceptibility to ovarian cancer (as high as 50% lifetime risk for ovarian, 85% for breast cancer if you have a mutation. Other ovarian cancer susceptibility genes may be identified by ongoing research. ...Read more

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Might infertility be hereditary?

Might infertility be hereditary?

Sometimes: Some causes of infertility (ovulatory disorders, uterine abnormalities, "possibly" endometriosis) can be inherited; some not. "infertility" is not inherited, it's too general a term. ...Read more

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Is endometriosis hereditary

Is endometriosis hereditary

Yes.: Not all patients with endometriosis have a family history, but many do. If you are having pelvic pain, severe pain with your periods or pain on penetration with intercourse, you should see your gynecologist. While you can not see endometriosis on an ultrasound, you can see other sources of pelvic pain. Robotic laparoscopic surgery is the best way to see endometriosis. ...Read more

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Is ovarian cancer genetic?

Is ovarian cancer genetic?

Sometimes: Certain genotypes such as the brca mutations have a higher incidence of ovarian cancer. ...Read more

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Wife--tubal reversal in 07. 13 miscarriages/ 1 tubal. Dna karyotyping &autoimmunity normal.How would genetics effect this?Blood types me a- / her o+.

Wife--tubal reversal in 07. 13 miscarriages/ 1 tubal. Dna karyotyping &autoimmunity normal.How would genetics effect this?Blood types me a- / her o+.

MTHFR?: Have they tested for the mthfr 677 ; 1298 genotypes yet? It is a very common cause of infertility and neural tube defects leading to miscarriages. The more abnormal genes you have, the worse the problems can be. Can treat with bellevue pharmacy "s8"supplement (msg for details).Also check her for antibodies to sperm. Would need ivf if +. Blood type could be an issue (abo incompatibility) rh is ok! ...Read more

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Are secondary sex characteristics linked to fertility in women?

Are secondary sex characteristics linked to fertility in women?

In a way: Normal fertility requires sexual maturity. Secondary sex characteristics (breasts, hips, pubic and axillary hair ) develop along a timeline to menstruation and sexual maturity. Assuming secondary characteristics have matured by certain age, they are not linked to fertility problems. Absent development can suggest problems, features like breast size or hair growth are largely irrelevant. ...Read more

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What are factors that affect male fertility?

What are factors that affect male fertility?

Many: Lack of sperm or azospermia can be due to either obstructive causes in the tract, from the testicle to the urethra, or from non-obstructive causes such as primary testicular dysfunction due to infection (mumps), history of surgery / trauma / chemo / radiation, or idiopathic (unknown). The biopsy should guide the next step in therapy as well as a hormonal panel, particularly fsh, sex chromosome. ...Read more

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Does conventional ivf increase risk of genetic defect of baby conceived?

Does conventional ivf increase risk of genetic defect of baby conceived?

IVF & genetic defect: There are genetic causes of infertility that could be passed on to the baby. Otherwise I don't think there is enough data to make conclusions - my opinion. ...Read more

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Will icsi eradicate genetic disorders?

NO: Icsi is a technique to insert the sperm into the egg. Icsi solves the problem of sperm that cannot penetrate the cumulus cells, zona pellucida (shell around the egg), and the egg membrane itself. Icsi is not a genetic treatment of any sort. Genetic ivf treatment is called preimplantation genetic diagnosis (pgd) or screening (pgs). I hope this brief answer helps. ...Read more

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Can lifestyle affect a genetic predisposition to cancer?

Yes and no: Genetic predisposition is what you are born with, for good or bad (like brca mutations causing breast and ovarian cancer). Can't do anything to change your genes although you can work to decrease the odds if you have a high risk gene. Lifestyle choices may increase the risk even more so avoiding unhealthy choices will be beneficial. In other words, change what you can but be aware of your risk. ...Read more

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Do ovum donors undergo genetic testing or pedigree evaluation?

Do ovum donors undergo genetic testing or pedigree evaluation?

Yes: Check with your rei specialist for details, but all ovum donors would be asked to report a detailed family history and would be tested for common recessive disorders, such as cystic fibroisis. Many programs would also request more extensive testing including a panel of 100 such recessive diseases, including such problems as spinal muscular atrophy, the askenazi jewish panel, fragile x, & more. ...Read more

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Are any genetic conditions treatable in utero?

Not directly: Currently there are no genetic discorders that can be treated in utero. There are consequences of certain disorders that can be treated however. The primary reason for knowing the genetic makeup of a baby in utero is for decision making and palnning outcomes. ...Read more

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Are choroid plexus cysts genetically inherited? If planning a family, should my wife and I have pre-pregnancy genetic testing?

Are choroid plexus cysts genetically inherited?  If planning a family, should my wife and I have pre-pregnancy genetic testing?

Whoa: Choroid plexus cysts are very common and almost always a non-problem. Further, they're not really hereditary. Your personal physician is the best person to advise you about any genetic risk. If somebody has a cyst and is concerned, get the facts from someone reliable. ...Read more

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Are cataracts genetic?

Are cataracts genetic?

Sometimes: There are a few inherited conditions in which cataracts are a part of the syndrome. Most are present at birth or form in early life. Otherwise cataracts mostly are an age related development. ...Read more

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Can genetic testing prevent birth defects in pregnancy?

Can genetic testing prevent birth defects in pregnancy?

Nope.: Genetic prenatal testing can detect many chromosomal or microscopic dna defects - but it cannot prevent birth defects! 2-4% of all newborns will have a minor or major birth defect and the vast majority of those have unknown genetic underpinnings at this time, although many of us are working to change that. Take Folic Acid 1-5 mg daily to prevent 75-95% of major neural/cardiac fetal anomalies! ...Read more

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