Doctor insights on:
Femara Risk Ovarian Cancer
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Not usually: There are some families who have increased rates of a variety of cancers, including papillary thyroid cancer, breast cancer, and colon cancer. But having one does not cause an risk for another; instead inherited genes put a person at increased risk for both. A person with a history of thyroid cancer should be sure to get recommended mammograms and colon tests. ...Read moreSee 1 more doctor answer
Related to spread: Metastatic refers to a cancer that has spread from the original site that it originated from to a more distant site in the body. For example, if a woman had ovarian cancer and it spread to the lungs then this would be consider metastatic disease. ...Read moreSee 1 more doctor answer
Sometimes: There is a familial disorder known as lynch syndrome which increases both the risk of colon cancer and endometrial (uterine) cancer. About 5% of all colon cancers are caused by lynch syndrome. If a family has multiple cases of both colon and endometrial cancer or colon cancer under the age of 40, lynch syndrome should be considered. ...Read moreSee 1 more doctor answer
Does having breast, endometrial, and ovarian cancer in family history increase one's risk of endometriosis?
Endo: Having family history of ovarian, colon and uterine cancer specially if these are first degree relatives will put you at risk for cancer not for endometriosis. I would recommend that you talk to your doctor and ask about a brca genetic testing to see if you are a carrier of the gene associated with these types of cancer. ...Read moreSee 2 more doctor answers
Minimal: If there is a risk, is with Clomid (clomiphene) after 12 months of use and the risk is minimal. The greatest risk is infertility itself and not the medications. In the grand majority of patients there is no reason to use Clomid (clomiphene) for 12 months. The treatment is usually changed if the patient has not conceived after 4-6 cycles. ...Read moreSee 1 more doctor answer
Need more details: I highly recommend you consult your oncology team and get evaluated by a gynecology oncologist. Since you are <50, it makes me concerned about a brca mutations (if you have not been tested, then get tested!). Ovarian cancer and breast cancer can be related, especially if brca is positive. If you have a estrogen positive tumor, then stopping the ovaries from making hormone may be beneficial. ...Read more
YES for ER positive: Oopherectomy has been proven to reduce recurrence in estrogen-receptor positive pre-menopausal women. Prior to tamoxifen, it was a commonly used treatment for metastatic disease and is now known to reduce recurrence in high-risk premenopausal hormone-receptor positive breast cancer, even without the use of other endocrine therapies. ...Read moreSee 3 more doctor answers
It can.: The most definitive study that looked at uterine cancer rates associated with tamoxifen found that women had twice the risk of developing uterine cancer, at a rate of 1 per 500 women per year. This rate is far lower than the rate of breast cancer prevention; thus, the benefits far outweigh the risks. A better alternative after menopause is aromatase inhibitors, which do not increase this risk. ...Read moreSee 1 more doctor answer
Increased risk...: ...is associated with increased age, women with a family history of ovarian or breast cancer, women with the genetic BRCA modifications, and certain ethnicities. These groups have a higher risk than the overall lifetime risk for women in the US of 1.6%. ...Read moreSee 1 more doctor answer
Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?
Individual: Yes, estrogen alone does increase the risk of uterine cancer over time. And yes the whi showed that the combination of a certain synthetic estrogen and a certain synthetic progestin increased the risk of breast cancer. But most specialists do not use those older types of synthetic hormones and with newer medications the risks are lower and different. So a balance can be achieved. ...Read more
- Talk to a doctor live online for free
- Does femara cause ovarian cancer?
- Ovarian cancer risk by age
- Endometriosis and ovarian cancer risk
- Ask a doctor a question free online
- Humira ovarian cancer risks
- Ovarian cancer risk calculator
- Femara cancer treatment
- Can femara help keep ovarian cancer from returning after surgery and chemo?
- Talk to a gynecologist online for free