Doctor insights on:
Femara Cause Osteoporosis
Possibly: Femara (letrozole) is an aromatase inhibitor. It works by decreasing the amount of estrogen produced in post-menopasual women. Anything that lowers estrogen level will take away its protective effect on bone, thus increasing the risk of fracture, osteopenia or osteoporosis. ...Read moreSee 1 more doctor answer
Currently it is better to think of osteoporosis as a condition where the bone is weakened, and can be managed or treated rather than cured. This is usually performed by dietary modifications, ingestion of supplemental calcium, vitamin d and a class of agents notice the bisphosphonates. These are usually delivered via oral or intramuscular injection on a weekly or monthly ...Read more
Immobilization: Hi. Both weight-bearing and muscle use are good for bone health. You're not weigh-bearing OR using muscles if you're immobilized. Skeletal mass and strength suffer. It appears that the cells that eat away bone (osteoclasts) are relatively more active than the cells that fill the eaten-out bone back in (osteoblasts), so there's a net loss of bone mass and bone architecture & urinary loss of calcium ...Read moreSee 1 more doctor answer
Can bilateral oopherectomy cause someone to have osteoporosis and is there a way to stop it from worsening?
Yes: Ovarian removal obviously lowers estrogen dramatically, which can lead to increasing rates of bone loss and possibly osteoporosis. Calcium, vitamin d and exercise are important. Estrogen can be prescribed if you and your doctor agree to use it. There are other medications which can prevent bone loss. Talk w/your doctor to see if you need them. ...Read more
Many things: Osteoporosis can be the result of low calcium, low Vitamin D, decreased bone production, increased bone turnover, disuse of a limb due to injury or pain, or other medical conditions such as hypothyroidism or kidney disease. Therefore, it is important to have osteoporosis evaluated with a physical and blood work so that the correct treatment can occur and prevent fractures. ...Read more
Powerful&PoorlyKnown: Steroid hormones (all derivatives of cholesterol) analogous to cortisol induce greater activity of osteoclasts (bone degrading cells) vs. Osteoblasts (bone forming cells). This has long been observed, both in spontaneously occurring & iatrogenic (doc, medication induced) cushing's disease. However, like many other issues, though always happens, this does not mean all the details are understood. ...Read more
Genetic factors: At age 31 genetic factors and estrogen deficiency would be the most likely causes. Less commonly cortisone or other steroids, anorexia, immobilization, and a variety of drugs such as blockers of stomach acid secretion and antidepressive agents may cause bone loss. Long term vitamin d deficiency may also be a factor. ...Read moreSee 2 more doctor answers
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