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Doctor insights on: Femara Cancer Treatment

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How effective is letrozole (Femara) for treating breast cancer?

How effective is letrozole (Femara) for treating breast cancer?

Variable: Depends on 1) whether the tumor is estrogen receptor positive, 2) stage of the cancer. If metastatic, it works better for bone and soft tissue metastases and not very well for liver and lung metastasizes. Often used as an adjuvant treatment after surgery and often with radiotherapy ...Read more

Dr. Barry Rosen
4,342 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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When is tamoxifen for breast cancer treatment?

When is tamoxifen for breast cancer treatment?

Chemotherapy: Tamoxifen is a very effective drug for the treatment of hormone-sensitive (estrogen receptor +) breast cancers. It may be used alone or in combination with traditional IV chemotherapy, depending on the cancer stage. Furthermore, tamoxifen has been shown to be effective reducing the chance of developing breast cancer in high-risk women ("chemoprevention"). ...Read more

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What is radiation therapy treatment for colon cancer?

What is radiation therapy treatment for colon cancer?

Energy beams: For certain types of colorectal cancer, energy beams are focused in the cancerous area. These beams are designed to kill cancer cells and decrease the chance of the tumor growing back. Depending on the situation, radiation can be used either before an operation or after an operation. ...Read more

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Does taking tamoxifen for breast cancer treatment induce cancer of the womb?

Does taking tamoxifen for breast cancer treatment induce cancer of the womb?

Small risk: Tamoxifen is asociated with a small (less than 5%) risk of uterine cancers, women on tamoxifen require regular gynecologic checkups every 6-12 months and high-risk women may need ultrasound screeenings too. ...Read more

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How effective is anastrozole (Arimidex) for treating breast cancer?

How effective is anastrozole (Arimidex) for treating breast cancer?

Good: it is a very good drug in preventing breast cancer relapse in patients who have had their breast tumors removed. prevents estrogen stimulation in patients with estrogen receptor positive breast cancer. ...Read more

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How effective is Xeloda (capecitabine) for metastatic breast cancer?

How effective is  Xeloda (capecitabine) for metastatic breast cancer?

It depends: As the first treatment for metastatic breast cancer, Xeloda (capecitabine) works in 40-60% of people treated. If it is the second, third or later treatment after failure of other agents, the effectiveness is much less. ...Read more

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Can radiation treatment and chemotherapy cure esophageal cancer?

Can radiation treatment and chemotherapy cure esophageal cancer?

Sometimes: The two main types of esophageal cancer are adenocarcinoma and squamous cell carcinoma. Cure with chemotherapy and radiation alone is much more likely with squamous cell carcinoma. The exact cure rate is dependent on the stage of the cancer, but cure with just chemotherapy and radiation is rare. ...Read more

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Can taking tamoxifen for breast cancer treatment induce cancer of the uterus ?

Can taking tamoxifen for breast cancer treatment induce cancer of the uterus ?

Maybe: There is a slight increased risk of endometrial cancer of 1 in 500 chance reported. The benefits of tamoxifen in treatment of breast cancer is much higher than the risk of endometrial cancer. Ask your oncologist and ob-gyn how best to follow or watch for this potential risk. ...Read more

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Does taking tamoxifen for breast cancer treatment cause cancer of the uterus ?

Does taking tamoxifen for breast cancer treatment cause cancer of the uterus ?

Yes: Tamoxifen has been shown to increase the risk of uterine cancer, not unlike estrogen replacement therapy, with an incidence of ~1:500. However, this is almost-always caught at its earliest stage, with very high cure rates. If you compare the benefit of tamoxifen for either treating or preventing breast cancer compared to this risk, the benefit far outweighs the risk. ...Read more

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How effective is capecitabine (Xeloda) for treating colon cancer?

How effective is capecitabine (Xeloda) for treating colon cancer?

Good: Xeloda by itself is similar to 5 FU regimen. However these days we tend to add other medications such as oxalipatin and sometimes avastin (bevacizumab) depending on the stage. ...Read more

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How effective is the IFL-Bevacizumab chemotherapy regimen for treating colon cancer?

How effective is the IFL-Bevacizumab chemotherapy regimen for treating colon cancer?

Better than chemo: Combining bevacizumab (BV)—a recombinant, humanized mAb targeting VEGF with irinotecan, fluorouracil (FU), and leucovorin (LV; IFL) has increased survival of patients with metastatic colorectal Ca compared with IFL It appears necessary to use combination therapy in treatment and has supported the concept that the use of immunochemotherapy improves results over chemo alone. ...Read more

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How effective is the FOLFIRI-Bevacizumab chemotherapy regimen for treating colon cancer?

How effective is the FOLFIRI-Bevacizumab chemotherapy regimen for treating colon cancer?

Moderately useful: FOLFIRI-Bev is the standard, commonly used first line chemotherapy for metastatic Colon cancer. It can add about 12 to 18 months extra to your life such that an average patient can live for 2 to 3 years(some live upto 5-6 years... depending on sites of metastases and their response to chemotherapy. You need tell us more about your history such as dates of diagnosis and treatments/results so far?? ...Read more

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Is chemo really an effective cancer treatment?

It depends: Chemotherapy is very effective for treatment of some cancers. It can be curative in some cases and prolong life in others. However, chemotherapy, due to its nature, is toxic, and any treatment with chemotherapy should involve a discussion of risks and benefits (and possible outcomes) before starting. ...Read more

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Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Same drugs as other: Same chemotherapy drugs are used for treating both types of colon cancer. The only difference is lack of benefit from EGFR inhibitors(Cetuximab and Panitumumab). Avastin (bevacizumab) also works in both types. I trust that you know there are 3 chemo drugs that are widely used(5FU or Capecitabine, Irinotecan and Oxaliplatin) ...Read more

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Can Abraxane and Avastin (bevacizumab) be used for treating ovarian cancer?

Can Abraxane and Avastin (bevacizumab) be used for treating ovarian cancer?

Yes it is an option: The standard therapy for ovarian cancer initially is still a taxane (usually Taxol) and Carboplatin. However, Abraxane is an effective taxane down the line for recurrences, and is potentially less toxic. Avastin (bevacizumab) has been combined safely with Abraxane and the two may be helpful for recurrence management. But the question is a bit difficult to answer concretely because circumstances differ. ...Read more

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Treatment for prostate cancer by stage.

Treatment for prostate cancer by stage.

Disease continuum: There is a disease continuum from localized disease through advanced metastatic castration resistant disease. Generally localized disease is treated with local therapies such as surgery or radiation and disease that either recurs or is more advanced is treated initially with hormonal therapy. Immune therapy and chemotherapy may be used after. ...Read more

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How effective is gemcitabine (Gemzar) for treating lung cancer?

How effective is gemcitabine (Gemzar) for treating lung cancer?

Mildly: Gemzar (gemcitabine), (gemcitabine) a form of chemotherapy can be used in non resectable lung cancer. It usually follows a couse of standard chemo such as Platinum/Taxol. When used in pancreatic Ca it is given with Abraxane, a form of Taxol which enhances Gemzar (gemcitabine) by a few weeks. After tumors respond to chemo which affects the tumor DNA, stem cells resistant to chemo reappear. Better results are now seen with anti PD-1. ...Read more

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How effectice is Xeloda (capecitabine) for metastatic breast cancer?

How effectice is Xeloda (capecitabine) for metastatic breast cancer?

Quite effective: Xeloda (capecitabine) is quite an effective drug and has been used in metastatic breast cancer. The response will be higher when it is combined with other chemotherapy agent- with additional possible side effects. Discuss further with you oncologist in detail. ...Read more

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Treatments for prostate cancer with bone metastasis?

Treatments for prostate cancer with bone metastasis?

Many: The first line of treatment for this is androgen deprivation. In addition, there are medicines which reduce the risk of fractures with Denosumab showing the most efficacy compared to zoledronic acid, however with some risk of significant side effects. For more extensive disease, a newer IV radium therapy has shown improved survival. Localized radiation can be effective for painful foci. ...Read more

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Dr. Michael Thompson
190 doctors shared insights

Cancer Treatment (Definition)

Treatment for cancer usually depends on type, stage, patient's performance status, age, comorbidities. For a list of treatments please ...Read more