Doctor insights on:
Femara Cancer Related Hormone
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Tamoxifen is given to breast cancer patients to suppress estrogen or both estrogen & progesterone?
Estrogen: Tamoxifen is given to individuals with specific breast cancers that are driven to grow by the presence of estrogen receptors. Tamoxifen interferes with the activity of estrogen in the breast, preventing cancer growth. The role of Progesterone receptors is unclear, though Progesterone receptors in breast cancer are generally associated with estrogen receptors, making tamoxifen an effective therapy. ...Read moreSee 2 more doctor answers
NO BUT INCREASE RISK: Hormone therapy does not cause breast cancer but it does increase your risk of breast cancer. According to the national nurses health study using hormone replacement therapy for 10-15 yrs increases risk about 20%, if used more than 15 yrs it doubles to around 40%. Talk to your doctor to help you decide how to better manage postmenopausal symptoms. ...Read more
Very low Risk: With due respect. The landmark study, whi, is called into question in so many ways. The nih spent millions to answer very little. As an re, i feel there are many facets to HRT and a careful and comprehensive evaluation of the literature supports a very minimal at best increase in breast cancer and the evidence points to the progestin component only (provera). Consultation warranted. ...Read moreSee 2 more doctor answers
Increases risk: Hormone replacement therapy (hrt) has been shown to increase one's risk for breast cancer if taken for longer than 5 years. The current recommendation is to take low doses for a limited amount of time and then stop. There are some other non hormonal medications that can be used to help manage menopausal symptoms. ...Read moreSee 3 more doctor answers
Not exponentially: Data from the whi (women's health initiative) study show that estrogen alone does not significantly increase the risk of breast cancer, especially if started within 5 years of menopause. However, estrogen + Progesterone (needed when women still have a uterus to prevent uterine cancer) increases the risk of breast cancer to about 2x the baseline risk. Progesterone appears to be the "bad guy". ...Read moreSee 2 more doctor answers
Can hormone fluctuations cause ovarian cancer? Can wild hormone fluctuations due to PMS or birth control pills cause ovarian cancer?
Is there a benefit to chemotherapy in hormone receptor positive, node positive postmenopausal breast cancer?
Often: There is increasing data based on the oncotype DX test in women with 1-3 positive notes that shows that some women will not get much benefit from chemo and some will get a great deal. It can be useful in cases where a woman is reluctant to take chemo. This is done on tissue that has been already removed. Most oncologists believe that women who have multiple positive nodes should get chemotherapy. ...Read moreSee 1 more doctor answer
Hormonal blockade: Depending upon your age and menstrual status your oncologist will help choose a medication to block the receptors for estrogen and Progesterone or one that will block the production of those hormones. These drugs minimize the ability of these hormones to stimulate the growth of breast and breast cancer cells. Some of them are associated with a risk of endometrial cancer but it is minimal. ...Read moreSee 2 more doctor answers
D/W oncologist: Treatment will depend not only the stage but also the biology of the cancer- whether it is estrogen positive, her2neu positive, whether it is lymph node positive or not. Also depends on your preference and overall health condition. Different test like oncotype dx, mammaprint can give you more info-re- recurrence risk of cancer and will be helpful in choosing the right therapy for you.D/w your md. ...Read moreSee 2 more doctor answers
No, a risk factor: Unopposed estrogen is a risk factor for uterine cancer but it does not always cause it. Unopposed estrogen means it is given without any Progesterone another female hormone. Somewhere between 4-8 out of every 1000 women receiving unopposed estrogen per year will get uterine cancer. Being obese probably makes the risk closer to 8/1000, whereas in thin women the risk is about 4/1000. ...Read more
A hormone (from greek ὁρμή, "impetus") is a chemical released by a cell or a gland in one part of the body that sends out messages that affect cells in other parts of the organism. Only a little amount of hormone is required to alter cell metabolism. In essence, it is a chemical messenger that transports a signal from ...Read more
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