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Doctor insights on: Femara Attack Joints

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Can femara (letrozole) attack the joints?

Can femara (letrozole) attack the joints?

It causes pain!: Femara doesn't really "attack" the joints, but it definitely causes joint pain! this occurs in 4 out of 10 women taking the drug. It is likely due to lowering of blood estrogen levels. Sometimes switching to another similar drug (anastrazole, aka arimidex) can help. If your vitamin d level is low, getting it back to normal levels with supplements can help the joint pain. ...Read more

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Dr. Stratos Christianakis
1,189 doctors shared insights

Joints (Definition)

Joints are parts of the body, formed by the cartilage-covered ends of bones plus the strong, flexible ligaments that attach the bones to one another. Movements at the joints in the body allow the different parts of the body to move in ...Read more


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Does metformin cause joint pain or could it be the femara (letrozole) i started taking in jan 2014?

Does metformin cause joint pain or could it be the femara (letrozole) i started taking in jan 2014?

Femara!!!: It is definitely the femara! almost half of women taking Femara get moderate to severe joint pain. Sometimes switching to a different aromatase inhibitor helps. Make sure your doctor knows you're having pain. If your vitamin d level is low, increasing it can improve the pain. But it's really a troublesome side effect, and i'm so sorry you have it. Ask your doc for relief so you stay on the drug! ...Read more

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Hi, i stopped taking femara (letrozole) two weeks ago - cold turkey and have been having a lot of headaches, dizziness, nausea, muscle and joint pains, tiredness?

Hi,  i stopped taking femara (letrozole) two weeks ago - cold turkey and have been having a lot of headaches, dizziness, nausea, muscle and joint pains, tiredness?

Withdrawal: Consult your gynecologist for a better way to discontinue your hormones. Tapering is generally better than abrupt discontinuation of any drug (absent severe immediate toxicity necessitating the discontinuation). ...Read more

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Is femara (letrozole) used as a fertility drug?

Yes: Although Femara (letrozole) is only fda approved for the treatment of certain types of breast cancer, it is also used off-label to stimulate ovulation in fertility treatments. It is sometimes used in the place of clomifene (clomid) for ovarian stimulation. ...Read more

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Does femara work better than clomid (clomiphene)?

No, similar success: In most studies comparing Clomid (clomiphene) and Femara the pregnancy rates are similar and neither has been found to be superior to the other. Femara for fertility is an "off-label" indication, meaning this drug was not designed for this purpose. There are pros and cons of both Clomid (clomiphene) and Femara and they have different side effect profiles. Talk to your doctor about what is best for you. ...Read more

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Does femara work the same as clomid (clomiphene)?

Does femara work the same as clomid (clomiphene)?

It depends on your c: No they are different classes of drugs. Femara causes reduction in estrogen levels and is often used for treatment of breast cancer whereas Clomid (clomiphene) is used for treating infertility. ...Read more

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How helpful is the fertility drug femara (letrozole)?

Very helpful: Femara or Letrozole is an oral ovulation induction medication. It works sometimes when Clomid (clomiphene) doesn't. It also helps pregnancies to occur when Clomid (clomiphene) fails. It seems to be very helpful especially in patients with pcos. The pregnancy rates are similar to Clomid (clomiphene) but the side effects are less and the multiple pregnancies seem to be also less. ...Read more