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Doctor insights on: Fast Acting Antihistamine

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Dr. Paul Carter
648 Doctors shared insights

Antihistamine (Definition)

Sedating and non-sedating antihistamines prevent and treat allergic reactions, and are ...Read more


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Are there any immediate acting allergy medications I can take other than Benadryl (diphenhydramine)?

Are there any immediate acting allergy medications I can take other than Benadryl (diphenhydramine)?

Several: OTC second generation antihistamines as cetirizine and loratadine, but read the labels and instructions carefully ...Read more

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Am taking 24hr alegra but my allergies still act up at night, so I take a Benadryl (diphenhydramine) at night too?

Am taking 24hr alegra but my allergies still act up at night, so I take a Benadryl (diphenhydramine) at night too?

Allergic rhinits: Instead of benadryl, (diphenhydramine) I recommend you to ask your doctor for a prescription of a nasal steroid to use once a day. Examples are flonase, nasaonex, Qnasl and nasacort. Another class of medicines your doctor can try is singulair, 10 mg, taken once a day. ...Read more

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I wanted to know I took benadryl (diphenhydramine) because my allergies are acting up and I'm stuffed up, I have a cough, I'm weeding because my asthma as well. Is it o?

I wanted to know I took benadryl (diphenhydramine) because my allergies are acting up and I'm stuffed up, I have a cough, I'm weeding because my asthma as well. Is it o?

Probably not: I presume you are asking whether it is ok to do some weeding when your nose is stuffed up and your asthma is not controlled. In general, the answer would be no since you are likely allergic to weed pollen and molds from the disturbed soil. It is also important for you to call your doctor about your asthma. Benadryl (diphenhydramine) or any other antihistamine has no decongesting action, nasal steroid does. ...Read more

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Just took 25 mg of Benadryl (diphenhydramine) will that counter-act/ make my Prozac and klonopin that I took earlier not effective?

Just took 25 mg of Benadryl (diphenhydramine) will that counter-act/ make my Prozac and klonopin that I took earlier not effective?

No it won’t: Taking benadryl (diphenhydramine) in addition to prozac and klonopin will not counteract the effects. Just be careful with taking it too close to the klonopin because they both cause drowsiness. ...Read more

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My doctor prescribed me trazodone 100 mg for sleep and I am now experiencing pins and needles all over. I took 4 Benadryl (diphenhydramine) to counter act.

My doctor prescribed me trazodone 100 mg for sleep and I am now experiencing pins and needles all over. I took 4 Benadryl (diphenhydramine) to counter act.

Oversedating: It is not a good idea to combine sedating medications. The trazadone was given to help you sleep and taking additional 4 Benadryl (diphenhydramine) which I assume is 100mg will add too much extra sedation on top. If the side effects of trazadone are bothersome I recommend discussing other options with your doctor instead of taking a lot of other medications to mask symptoms. ...Read more

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A small neck rash a few days prior to getting a full body rash very quickly. Appears in a.M. Before foods or meds. Clears fast with no antihistamine?

A small neck rash a few days prior to getting a full body rash very quickly. Appears in a.M. Before foods or meds. Clears fast with no antihistamine?

Urticaria: Urticaria refers to a group of disorders affecting adults and children, in which red patches and weals occur in the skin. A wheel is a swelling of the surface skin.
The skin swelling seen in urticaria is due to the release of chemicals such as histamine from mast cells in the skin which causes small blood vessels to leak. Treatment is with antihistamine or avoidance of the causative agent. ...Read more

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I took a Zyrtec and Flonase this morning. Would like to take muscinex fast max with antihistamine for the evening and wondering if that is ok?

I took a Zyrtec and Flonase this morning. Would like to take muscinex fast max with antihistamine for the evening and wondering if that is ok?

Yes, but: Be cautious still with antihistamines overdose, i.e. stay with only one antihistamine in the following days, till the cold symptoms are over, good that you asked, always exercise caution with multiple medications ...Read more

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Fast and easy ways to reduce redness in the morning before school? Wash with cold water, witch hazel, antihistamine?

Fast and easy ways to reduce redness in the morning before school? Wash with cold water, witch hazel, antihistamine?

Red face: You may have only sensitive skin. You may have high blood pressure causing the redness. See your dermatologist to confirm my answers. ...Read more

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How fast would a rash subside when using: antibiotics, cortisone, antihistamines and topical creams at the same time? Any chance it would do nothing?

How fast would a rash subside when using: antibiotics, cortisone, antihistamines and topical creams at the same time? Any chance it would do nothing?

Rash: It all depends on the cause of the rash. If it is an allergic rash for something topical like soap for instance then topical cortisone cream would be a good option for itching and redness. Antihistamines would help redness and swelling for an allergy rash. Antibiotic ointment help for topical bacterial infections. If you are having shingles (herpes zoster) none of these will help. ...Read more

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When ever I'm not taken an antihistamine like Clariten or Zyrtec (cetirizine) and I am walking fast like to class I get extremely itchy like in my thigh region?

When ever I'm not taken an antihistamine like Clariten or Zyrtec (cetirizine) and I am walking fast like to class I get extremely itchy like in my thigh region?

Itchy: You might have dermatographism which is a physical urticaria from rubbing the skin. Rubbing, pressure or scratching your skin can cause a hive or wheal to develop which can be intensely itchy Your doctor can test you for this if you are not taking antihistamines at the time you are examined. Antihistamines are an effective treatment of this condition ...Read more

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Are there any short acting anti-histamines? (i often have insomnia in the early morning when it is too late to take a unisom.)

Are there any short acting anti-histamines? (i often have insomnia in the early morning when it is too late to take a unisom.)

Yes: Sounds like you are looking for an antihistamine for its sedative effects. Diphenhydramine is marketed as Benadryl (diphenhydramine) for treatment of hives and allergic rhinitis and sominex for insomnia. The dose is the same 25-50 mg for adults. Diphenhydramine begins to work in 30 minutes. Its effects last about 4-6 hours. ...Read more

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What is the best OTC antihistamine?

What is the best OTC antihistamine?

OTC antihistamines: The second generation zyrtec, allergra or Claritin (loratadine) are comparative. None are perfect. Zyrtec is slightly more likely to make you tired ot sleepy. Often one works a little better than another and I adise you to test all three. ...Read more

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Is antihistamine harmful to the body?

Is antihistamine harmful to the body?

No: Antihistamines are a class of medication used since the 1940s. They are used to treat allergic conditions and are very safe. The newer generation antihistamines have even less side effects compared to first generation or old antihistamines. ...Read more

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When should you take an antihistamine?

Multiple reasons: Depending on the type of antihistamine used they can be used to treat things such as allergy symptoms, nausea, dizziness, motion sickness, anxiety, itching, and difficulty sleeping. ...Read more

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Is there an herb which can be used as an antihistamine?

Yes: Butterbur has antihistamine-like effects. It can be found at health food stores. ...Read more

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Is Flixonase an antihistamine?

Steroid Nasal Spray: Flixonase or Flonase (fluticasone proprionate) is a steroid nasal spray commonly used to treat allergic rhinitis by decreasing the allergic inflammation in the nasal mucosa. It is not an antihistamine. ...Read more

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Is there an antihistamine cream?

Yes, but avoid: Benadryl (diphenhydramine) cream is available. While some people find temporary relief for insect bites with this, in general it is not very effective compared to other antihistamines taken as pills or tabs. For generalized rash, it really doesn't make sense. ...Read more

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Does antihistamine make you drowsy?

Older ones do: First generation antihistamines (benadryl, clor-pheramine, atarax) cross the blood brain barrier and cause lethargy.
Second generation (allegra, claritin, zyrtec, xyzal, (levocetirizine) clarinex) cause the blood brain barrier at a much lesser amount and more targeted to the h1 receptor. ...Read more

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Can you use antihistamine and wine?

Can you use antihistamine and wine?

Not a good idea: Antihistamines (especially the older ones such as benadryl) can cause drowsiness and impairment and this can be worsened by the effect of alcohol even at regular doses. There are other allergy medications available that can be taken if a glass of wine is desired. ...Read more

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Is it ok to take antihistamines with?

With what?: If you are thinking about drinking alcohol, do not do it. Antihistamines might potentiate the effect of alcohol. ...Read more

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Can you take antihistamine with codeine?

Can you take antihistamine with codeine?

Yes: There is a medication called tussionex that combines an older antihistamine (chlorpheniramine) with hydrodocone (similar to codeine). This medication is especially effective for severe irritant cough. It is important to carefully follow dosing directions. ...Read more

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Is it safe to take an antihistamine daily?

Is it safe to take an antihistamine daily?

Yes but why: Although antihistamines are a very safe class of medications, the better question is why is there a need to take them daily? If antihistamines are being taken for treatment of nasal symptoms, see an allergist to identify the trigger. ...Read more

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Does an antihistamine help IC? If so how?

Does an antihistamine help IC? If so how?

IC: I commonly use anti histamine for my IC patients. Exciting histamine receptors in the bladder can stimulate inflammation. Similar responses are seen in sinus and stomach. The antihistamine therefore blocks one possible arm of the inflammatory cycle. ...Read more

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Which antihistamine dries up drainage best?

Which antihistamine dries up drainage best?

1st generation: As diphenhydramine, because of more anticholinergic effects, but would cause more sedation, read the labels well, don't drive or operate machinery while using them, if they still don't work, see your doctor for better diagnosis and management ...Read more

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Which is the best antihistamine for children?

Which is the best antihistamine for children?

Several are good: Loratedine (Alavert, Claritin), Cetirizine (Zyrtec)and Fexofenadine (Allegra)are all effective. Dyphenhydramine (Benadryl) is short acting so if you want the reaction not to come back in the middle of the night then one of the above would be better. Remember that you should not give children under 2 antihistamines without checking with your doctor. Between 2-4 y/o you should also ask. Not for colds ...Read more

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Is loratadine the best antihistamine out there?

Which one works: The best for you is the best one for you. ...Read more

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How long do antihistamines stay in your system?

72 hrs: The biologic effects no longer than 72 hours even though the drug may still be detectable for up to a couple of weeks with certain antihistamines. ...Read more

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Docs, what's a good yr round OTC antihistamine?

Whatever works: There are two important considerations. Efficacy and side effects. Caution must be taken with combination meds (antihistamines along with decongestants). Men with prostate issues and anyone with cardiac/BP issues.
Also glaucoma can be affected especially by first generation antihistamines such as Benadryl (diphenhydramine). Best bet, ask your doctor :-) ...Read more

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How can I tell if my antihistamines are working?

How can I tell if my antihistamines are working?

Feeling better?: The symptoms that they are intended to treat improve. ...Read more

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Is it ok to take three different antihistamines?

Not a good idea: Unless specifically instructed by an allergist. I have only seen people on more than one antihistamine for severe recurrent hives (urticaria). Taking too many antihistamines at once can cause issues with urinary retention and other problems. ...Read more

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I am allergie to antihistamine, can I take pepid?

I am allergie to antihistamine, can I take pepid?

Describe allergy: Antihistamines are traditionally used to treat allergic reactions. I am curious as to what exactly what happens to you in response to specific antihistamines: benadryl, (diphenhydramine) zyrtec, Claritin etc.
Pepcid is a medication that inhibits acid production by the stomach and would be helpful for treatment of heartburn, indigestion (dyspepsia), gastitis (stomach inflammation) or reflux of acid ...Read more

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Will out of date antihistamine tablets still work?

Maybe: Medications that have passed the expiration may still work, but the pharmaceutical manufacturer cannot guarantee their effectiveness. The longer the medication is out of date, the more likely they are less effective. ...Read more