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Doctor insights on: Family History Of Pernicious Anemia

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I tested positive for ana, and have a family history of lupus and pernicious anemia. What do I do now?

I tested positive for ana, and have a family history of lupus and pernicious anemia. What do I do now?

Wait: Many normal people have low-titer positive ana's and they mean nothing by themselves. If you have symptoms suggestive of lupus, continue the workup and consider seeing a rheumatologist. If you have a family history of pernicious anemia, you'd do well to get a serum B12 assay every few years. ...Read more

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Family History (Definition)

A family history consists of information about disorders suffered by the relatives of a patient. The history can help the patient identify diseases that he or she may be susceptible to, and help the patient to ...Read more


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Is there a specific blood test to diagnose pernicious anemia? I have a family history. My doctor told me I have borderline B12 deficiency.

Is there a specific blood test to diagnose pernicious anemia?  I have a family history. My doctor told me I have borderline B12 deficiency.

Pernicious anemia: Yes your doctor can run a battery of tests including a cbc, peripheral blood smear, a serum b 12 level, and a reticulocyte count. These usually will help to diagnose the condition. Sometimes methylmalonic acid and homocysteine levels will be drawn to help with the diagnosis. ...Read more

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B12 level 500 folate level 7, dr prescribed folic acid when previously had b12 injections, is this beneficial?, pernicious anemia runs in the family

B12 level 500 folate level 7, dr prescribed folic acid when previously had b12 injections, is this beneficial?, pernicious anemia runs in the family

Need both: You B12 level is normal while folic acid level is borderline. Please follow your doctor's advice about taking the two vitamins at the recommended intervals. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex. ...Read more

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Does pernicious anemia run in families?

Rarely: Most cases of pernicious anemia are acquired due to immune destruction of the stomach cells which produce intrinsic factor. This results in poor absorption of B12 from food and patients get anemic as a result. Only rarely can children get this as a congenital causes. ...Read more

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Does hashimoto's run in families? And does it have potential to cause pernicious anemia?

Does hashimoto's run in families? And does it have potential to cause pernicious anemia?

Yes! To both!!: Both may be autoimmune diseases and frequently are hereditary! Both are very easily diagnosed by lab tests! See your physician if you think you have either of these illnesses! ...Read more

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What symptoms of pernicious anemia are the most common?

What symptoms of pernicious anemia are the most common?

Fatigue: In pernicious anemia, there is no vitamin B12 absorption which causes low red blood cell production and leads to severe anemia. This causes fatigue most comonly. ...Read more

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How to treat pernicious anemia?

How to treat pernicious anemia?

B-12 deficiency: Unless there is an intestinal parasite, we usually just do blood studies to confirm and supplement vitamin b-12 using 1000 mcg injected monthly, i.M. Some pts will absorb sufficient amounts by mouth or intranasal routes, but most efficient to inject. ...Read more

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Is there a cure for pernicious anemia?

Is there a cure for pernicious anemia?

Treatable: This condition can be well treated with life-long use of B12 injections or nasal sprays and results in normalisation of the blood counts. ...Read more

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Does methadone cause pernicious anemia?

Does methadone cause pernicious anemia?

Not likely: Methadone is a very strong opioid medication, with a long list of serious side effects. But pernicious anemia is NOT one of them. Contact your doctor for specific information about your case, re your anemia and specific doses of methadone you are taking. Anemia may be related to other meds you are taking, or an underlying illness. Check with your MD. ...Read more

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Is pernicious anemia genetically caused?

Not usually: Pernicious anemia is caused by vitamin B12 or Folic Acid deficiency. It may be associated with gastrointestinal or liver problems and should be investigated by your physician. ...Read more

Pernicious Anemia (Definition)

A decrease in red blood cells when the body can't ...Read more


Dr. Steven Ginsberg
1,273 doctors shared insights

Anemia (Definition)

Any condition where there is a decrease in the red blood ...Read more