Doctor insights on:
Family History Of Pernicious Anemia
I tested positive for ana, and have a family history of lupus and pernicious anemia. What do I do now?
Wait: Many normal people have low-titer positive ana's and they mean nothing by themselves. If you have symptoms suggestive of lupus, continue the workup and consider seeing a rheumatologist. If you have a family history of pernicious anemia, you'd do well to get a serum B12 assay every few years. ...Read moreSee 1 more doctor answer
It is a decline in the amount of red cells in the circulation as a result of impaired production in the bone marrow resulting from a lack of vitamin b12. This is most commonly as a consequence of impaired absorption due to an autoimmune condition affecting the stomach lining. If untreated, it may also lead to brain and spinal cord problems. It is easily ...Read more
Is there a specific blood test to diagnose pernicious anemia? I have a family history. My doctor told me I have borderline B12 deficiency.
Pernicious anemia: Yes your doctor can run a battery of tests including a cbc, peripheral blood smear, a serum b 12 level, and a reticulocyte count. These usually will help to diagnose the condition. Sometimes methylmalonic acid and homocysteine levels will be drawn to help with the diagnosis. ...Read moreSee 1 more doctor answer
Rarely: Most cases of pernicious anemia are acquired due to immune destruction of the stomach cells which produce intrinsic factor. This results in poor absorption of B12 from food and patients get anemic as a result. Only rarely can children get this as a congenital causes. ...Read moreSee 1 more doctor answer
Yes! To both!!: Both may be autoimmune diseases and frequently are hereditary! Both are very easily diagnosed by lab tests! See your physician if you think you have either of these illnesses! ...Read more
Due 2 B12 deficiency: It is a decline in the amount of red cells in the circulation as a result of impaired production in the bone marrow resulting from a lack of vitamin b12. This is most commonly as a consequence of impaired absorption due to an autoimmune condition affecting the stomach lining. If untreated, it may also lead to brain and spinal cord problems. It is easily treatable with replacement therapy. ...Read moreSee 2 more doctor answers
Cobalamin therapy: Try a trial of vitamin B12 (cobalamin) first and have a physician to repeat lab to ensure adequate dose. Also it may need additional therapies for cobalamin deficiency due to underlying diseases involving intestine or pancreas. Please check for Folic Acid deficiency as well and this may be related to nutritional deficiency. If you are a vegetarian, please take vitamin B12 daily. ...Read moreSee 1 more doctor answer
Not usually.: Classical pernicious anemia is caused by auto-antibodies against intrinsic factor-producing parietal cells of the stomach. Treatment is lifelong vitamin B12 administration, which is safer than using immunosuppressive medications that could lead to severe infections. Other kinds of B12 deficiency can possibly cured depending on the cause. ...Read more
Low blood count is also known as Anemia. Anemia is a condition in which the body has a decreased amount of healthy red blood cells, which normally provide oxygen to body tissues. Common causes may include certain medications, chronic diseases such as cancer, a poor ...Read more
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