Doctor insights on:
Family History Of Pernicious Anemia
I tested positive for ana, and have a family history of lupus and pernicious anemia. What do I do now?
Wait: Many normal people have low-titer positive ana's and they mean nothing by themselves. If you have symptoms suggestive of lupus, continue the workup and consider seeing a rheumatologist. If you have a family history of pernicious anemia, you'd do well to get a serum B12 assay every few years. ...Read moreSee 1 more doctor answer
Is there a specific blood test to diagnose pernicious anemia? I have a family history. My doctor told me I have borderline B12 deficiency.
Pernicious anemia: Yes your doctor can run a battery of tests including a cbc, peripheral blood smear, a serum b 12 level, and a reticulocyte count. These usually will help to diagnose the condition. Sometimes methylmalonic acid and homocysteine levels will be drawn to help with the diagnosis. ...Read moreSee 1 more doctor answer
B12 level 500 folate level 7, dr prescribed folic acid when previously had b12 injections, is this beneficial?, pernicious anemia runs in the family
Need both: You B12 level is normal while folic acid level is borderline. Please follow your doctor's advice about taking the two vitamins at the recommended intervals. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex. ...Read moreSee 1 more doctor answer
Rarely: Most cases of pernicious anemia are acquired due to immune destruction of the stomach cells which produce intrinsic factor. This results in poor absorption of B12 from food and patients get anemic as a result. Only rarely can children get this as a congenital causes. ...Read moreSee 1 more doctor answer
Yes! To both!!: Both may be autoimmune diseases and frequently are hereditary! Both are very easily diagnosed by lab tests! See your physician if you think you have either of these illnesses! ...Read more
B-12 deficiency: Unless there is an intestinal parasite, we usually just do blood studies to confirm and supplement vitamin b-12 using 1000 mcg injected monthly, i.M. Some pts will absorb sufficient amounts by mouth or intranasal routes, but most efficient to inject. ...Read more
Not likely: Methadone is a very strong opioid medication, with a long list of serious side effects. But pernicious anemia is NOT one of them. Contact your doctor for specific information about your case, re your anemia and specific doses of methadone you are taking. Anemia may be related to other meds you are taking, or an underlying illness. Check with your MD. ...Read more
No: Unaware of any association. True pernicious anemia is an autoimmune disease, caused by antibodies to the cells in our stomachs that produce intrinsic factor, which is needed to absorb vitamin B12 from our intestines. It may be hereditary or acquired. There are other causes of B12 deficiency, including stomach and intestinal diseases/surgery, and lack of B12 in diet. A hematologist can help. ...Read moreSee 1 more doctor answer
Certainly: Pernicious anemia is due to vitamin B12 deficiency. Alcohol in many ways can contribute to B12 deficiency: 1. Interferes with b vitamin absorption - alcoholics also do not have enough b vitamins in their diet 2. May cause gastritis leading to poor acid secretion in stomach (acid helps B12 absorption) 3. May cause intestinal damage leading to malabsorption. Thus, better to avoid alcohol! ...Read more
It can: Pernicious anemia (a severe type of vitamin B12 deficiency) can cause memory problems, irritability, and dementia. Dementia goes beyond having memory problems, and can include difficulties with understanding, reasoning, handling multi-step tasks, and can be accompanied by personality changes. Symptoms generally improve with treatment. ...Read more
The other way around: Achlorhydria (lack of adequate gastric acid production and secretion) is one of the causes of pernicious anemia and not the other way around. Normal gastric acid is essential for adequate absorption of vitamin b-12. Vitamin b-12 deficiency in turn causes pernicious anemia. ...Read moreSee 1 more doctor answer
Not at all: Pernicious anemia results from poor dietary uptake of vitamin b12, usually from a loss of certain cells in your stomach. These cells secrete intrinsic factor, necessary for absorption of vitamin b12. Treatment is B12 shots, potentially. Leukemia is cancer. Treatment is chemotherapy. ...Read more
See below: B-12 anemia is a deficiency in vitamin b-12 (cobalamin). Pernicious anemia is a deficiency or lack in intrinsic factor (produced by cells in the stomach) which is a protein essential for absorption of vitamin B12 in the ileum (small intestine). Pernicious anemia requires replacement of intrinsic factor &/or b-12. B-12 anemia needs only b-12 supplementation. ...Read more
It is easy to Diagno: Pernicious anemia is caused by Vitamin B12 deficiency. Therefore a Blood test can measure the B12 level in the blood and give you/your doctor the answer to your question. It is usually associated with larger sized red cells(Macrocytic Anemia) and bone marrow shows megaloblasts. ...Read more
Can you clarify?: If you have pernicious anemia and aren't effectively treated, you will first lose your mind and then your life. If by "B12 intolerance" you simply mean you cannot absorb the vitamin orally, this is common and you'll need monthly injections. If you believe that the supplement makes you sick -- as it claimed on some "pop" websites -- I'm skeptical but you'll need to get specialist consultation. ...Read more
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