Top
20
Doctor insights on: Family History Genetics Birth Defects

Share

Genetic (Definition)

From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more


2

2
Late 30s couple ttc for 1st time. No family history of autism/downs & both fit & healthy. What is % of risk for autism/birth defects?

If you'll be 39 at: Delivery, the chance to have a child diagnosed with Down syndrome at birth is 1 in 137 (a little < 1%); the chance to have a child diagnosed with any chromosome abnormality (including down syndrome) at birth is 1 in 83 (slightly > 1%). Autism risks? With paternal age, low maternal folate (folic acid) levels esp. At conception-10 wks. & some prenatal infections like rubella or flu. Ask your OB @ screening. ...Read more

See 1 more doctor answer
3

3
Sickle cell anemia:is this birth defect only due to genetics?

Yes: It is a defect present from birth, yes. Would I call it a birth defect, no. It is a genetically derived abnormality in the metabolism of hemoglobin that results in sickling of the red cells under some circumstances. As a metabolic disease, it is inherited in a similar fashion to pku or cystic fibrosis. The term birth defect is more appropriate for a kid with malformation of an organ or body part. ...Read more

4

4
What genetic birth defects are associated when two first cousins have a baby?

What genetic birth defects are associated when two first cousins have a baby?

Autosomal recessive: There is increased risk of autosomal recessive type genetic disorders when close family members have a baby together. There are many of them but some examples include cystic fibrosis, sickle cell anemia, and Tay-Sachs disease. ...Read more

5

5
Is clinodactyly a genetic disorder, birth defect?

Is clinodactyly a genetic disorder, birth defect?

Yes, but. ....: Clinodactyly is a curve of one or more fingers, which is pretty common, especially for the pinkies, and no big deal at all. Technically it's a minor birth defect and usually not a sign of any problem. But sometimes it's one component of a rare genetic syndrome, like wahab syndrome (http://omim. Org/entry/615170) or a more common one, like down syndrome. I have a little clinodactyly myself! ...Read more

6

6
Can genetic testing prevent birth defects in pregnancy?

Can genetic testing prevent birth defects in pregnancy?

Nope.: Genetic prenatal testing can detect many chromosomal or microscopic dna defects - but it cannot prevent birth defects! 2-4% of all newborns will have a minor or major birth defect and the vast majority of those have unknown genetic underpinnings at this time, although many of us are working to change that. Take Folic Acid 1-5 mg daily to prevent 75-95% of major neural/cardiac fetal anomalies! ...Read more

See 2 more doctor answers
7

7
First baby born with birth defects and died after delivery. Will second one have same problem. Nobody has defects in the family?

First baby born with birth defects and died after delivery. Will second one have same problem. Nobody has defects in the family?

More info needed: I would add that it depends on the type of defects present and whether the risk is based in genetic inheritance. If there was a pregnancy related cause, your OB Gyn physician can further advise. Many healthy infants are born to mothers with a similar history, but more information is needed to answer. ...Read more

See 1 more doctor answer
8

8
If a mother has a history of genital herpes, what are the odds of a baby having birth defects both for c-section and vaginal birth?

If a mother has a history of genital herpes, what are the odds of a baby having birth defects both for c-section and vaginal birth?

Varies: Birth defects are not an issue with maternal herpes. The baby is at risk of a severe infection from the germ. The risk period begins with the opening of the bag of waters if mom is actively shedding the virus during a recognized or silent outbreak. The germ can travel into babies system & lay dormant for a while or immediately cause infection. A c-section before labor starts can avoid the risk. ...Read more

See 1 more doctor answer
9

9
Can I drink reed's extra ginger brew (26mg fresh ginger) in 1st trimester? I have been for m/s, but read too much ginger can cause birth defects & m/c

Can I drink reed's extra ginger brew (26mg fresh ginger) in 1st trimester? I have been for m/s, but read too much ginger can cause birth defects & m/c

Safe in moderation: It is wise to be cautious re: the use of all herbs in the 1st trimester ; yes, too much ginger may be harmful. Research shows up to 1000 mg a day in divided doses is safe ; effective so the 26 mg in reed's ginger brew is quite safe. However, it has lots of sugar so consider making fresh ginger tea with honey to sweeten it. See http://www. Drweil. Com/drw/u/qaa400749/avoid-ginger-while-pregnant. Html. ...Read more

10

10
Can certain foods and drink cause birth defect?

Can certain foods and drink cause birth defect?

YES, . ..Some causes:: Alcohol; excessive caffeine; mercury: shark, swordfish, king mackerel, tilefish have highest amounts of mercury, can cause brain damage). Bluefish, striped bass, salmon, pike, trout, and walleye: high contamination of polychlorinated biphenyls. Some fish used for sushi; herbicides used in vegetables (e.g. Glyphosate used in genetically modified soy bean), low Folic Acid containing food. ...Read more

11

11
How can I know if my baby will have birth defects or deformities?

How can I know if my baby will have birth defects or deformities?

Ultrasound: Ultrasounds and genetic screening in pregnancy can identify many abnormalities before a baby is born. There are limitations to the screening though, neither test is capable of identifying every possible problem, but are good for picking up major problems. ...Read more

See 2 more doctor answers
12

12
What to do if I lived near a "superfund site", did it cause my child's birth defects?

What to do if I lived near a "superfund site", did it cause my child's birth defects?

No way to know: Birth defects can have soooo many possible causes, there is really no way to know if it's from your environment. It could also have been from a virus you had during pregnancy, defects in your genetic code/dna, something you ate undercooked, cigarette smoke you were exposed to, a vitamin deficiency. It is difficult if not impossible to pinpoint causes of most birth defects. ...Read more

15

15
Why does appalachia have so many people with birth defects?

Why does appalachia have so many people with birth defects?

In born: One theory of birth defects is genetic variabilty and lack of. If the population is enclosed with little or no outside mixing then the genetic pool is smaller. Recurrence of certain defects repeats and does not become diluted and lesser expression. ...Read more

16

16
Anyone have a child with omphalocele and other birth defects?

Anyone have a child with omphalocele and other birth defects?

Patient: Have a patient with omphalocele which happens to be a isolated defect. Often it is associated with other defects such as cardiac. ...Read more

17

17
What are the odds that my child will be born with birth defects?

What are the odds that my child will be born with birth defects?

2-4% like EV1 else.: All couples have a 2-4% risk of congenital defects in their offspring. Some have increased risk - e.g. Obese mothers, pregestational diabetics, epileptics, women with previously affected children etc. Take Folic Acid 1-5mg orally daily throughout your reproductive life to decrease the risk of preterm birth and certain serious congenital defects (spina bifida, anencephaly, heart anomalies)! ...Read more

See 1 more doctor answer
19

19
Does abnormal sperm shape cause birth defects?

Does abnormal sperm shape cause birth defects?

Unlikely: Since millions of sperm are involved in the race for the egg, it is the abnormal sperm that don't swim as well and are not likely to succeed in fertilizing an egg. ...Read more

See 1 more doctor answer
20

20
Do amniotic sac disorders cause birth defects?

Amniotic Fluid: Best discussed with your ob.
Too much or too little amniotic fluid is associated with abnormalities in development and pregnancy complications. Differences in the amount of fluid may be the cause or the result of the problem. ...Read more

See 1 more doctor answer

Family History (Definition)

A family history consists of information about disorders suffered by the relatives of a patient. The history can help the patient identify diseases that he or she may be susceptible to, and help the patient to ...Read more


Dr. Nikolaos Zacharias
841 Doctors shared insights

Congenital Abnormalities (Definition)

Abnormalites that are present at birth. Also known as birth defects. For example- cleft palate is a congenital abnormalities. Another example congenital heart disease is the presence of a ...Read more