Doctor insights on:
Family History Genetics Birth Defects
Birth defects: Something you are born withGet a more detailed answer ›
From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more
Late 30s couple ttc for 1st time. No family history of autism/downs & both fit & healthy. What is % of risk for autism/birth defects?
If you'll be 39 at: Delivery, the chance to have a child diagnosed with Down syndrome at birth is 1 in 137 (a little < 1%); the chance to have a child diagnosed with any chromosome abnormality (including down syndrome) at birth is 1 in 83 (slightly > 1%). Autism risks? With paternal age, low maternal folate (folic acid) levels esp. At conception-10 wks. & some prenatal infections like rubella or flu. Ask your OB @ screening. ...Read more
Yes: It is a defect present from birth, yes. Would I call it a birth defect, no. It is a genetically derived abnormality in the metabolism of hemoglobin that results in sickling of the red cells under some circumstances. As a metabolic disease, it is inherited in a similar fashion to pku or cystic fibrosis. The term birth defect is more appropriate for a kid with malformation of an organ or body part. ...Read more
Yes, but. ....: Clinodactyly is a curve of one or more fingers, which is pretty common, especially for the pinkies, and no big deal at all. Technically it's a minor birth defect and usually not a sign of any problem. But sometimes it's one component of a rare genetic syndrome, like wahab syndrome (http://omim. Org/entry/615170) or a more common one, like down syndrome. I have a little clinodactyly myself! ...Read more
Nope.: Genetic prenatal testing can detect many chromosomal or microscopic dna defects - but it cannot prevent birth defects! 2-4% of all newborns will have a minor or major birth defect and the vast majority of those have unknown genetic underpinnings at this time, although many of us are working to change that. Take Folic Acid 1-5 mg daily to prevent 75-95% of major neural/cardiac fetal anomalies! ...Read more
First baby born with birth defects and died after delivery. Will second one have same problem. Nobody has defects in the family?
More info needed: I would add that it depends on the type of defects present and whether the risk is based in genetic inheritance. If there was a pregnancy related cause, your OB Gyn physician can further advise. Many healthy infants are born to mothers with a similar history, but more information is needed to answer. ...Read more
If a mother has a history of genital herpes, what are the odds of a baby having birth defects both for c-section and vaginal birth?
Varies: Birth defects are not an issue with maternal herpes. The baby is at risk of a severe infection from the germ. The risk period begins with the opening of the bag of waters if mom is actively shedding the virus during a recognized or silent outbreak. The germ can travel into babies system & lay dormant for a while or immediately cause infection. A c-section before labor starts can avoid the risk. ...Read more
Can I drink reed's extra ginger brew (26mg fresh ginger) in 1st trimester? I have been for m/s, but read too much ginger can cause birth defects & m/c
Safe in moderation: It is wise to be cautious re: the use of all herbs in the 1st trimester ; yes, too much ginger may be harmful. Research shows up to 1000 mg a day in divided doses is safe ; effective so the 26 mg in reed's ginger brew is quite safe. However, it has lots of sugar so consider making fresh ginger tea with honey to sweeten it. See http://www. Drweil. Com/drw/u/qaa400749/avoid-ginger-while-pregnant. Html. ...Read more
YES, . ..Some causes:: Alcohol; excessive caffeine; mercury: shark, swordfish, king mackerel, tilefish have highest amounts of mercury, can cause brain damage). Bluefish, striped bass, salmon, pike, trout, and walleye: high contamination of polychlorinated biphenyls. Some fish used for sushi; herbicides used in vegetables (e.g. Glyphosate used in genetically modified soy bean), low Folic Acid containing food. ...Read more
No way to know: Birth defects can have soooo many possible causes, there is really no way to know if it's from your environment. It could also have been from a virus you had during pregnancy, defects in your genetic code/dna, something you ate undercooked, cigarette smoke you were exposed to, a vitamin deficiency. It is difficult if not impossible to pinpoint causes of most birth defects. ...Read more
Besides Diabetes: The answer to your question is yes. ...Read more
2-4% like EV1 else.: All couples have a 2-4% risk of congenital defects in their offspring. Some have increased risk - e.g. Obese mothers, pregestational diabetics, epileptics, women with previously affected children etc. Take Folic Acid 1-5mg orally daily throughout your reproductive life to decrease the risk of preterm birth and certain serious congenital defects (spina bifida, anencephaly, heart anomalies)! ...Read more
Best discussed with your ob.
Too much or too little amniotic fluid is associated with abnormalities in development and pregnancy complications. Differences in the amount of fluid may be the cause or the result of the problem. ...Read more
Traditional marriage: There is a tradition of marriage in many countries, especially those with a large muslim population, of marrying a first cousin or other relative. This increases the chance of an inherited defect in the offspring. Also there are large portions of the population with inadequate prenatal care which also causes an increase in problems at birth. ...Read more
No known value: There is no one value that one can say causes birth defects. More important is at what stage of fetal development exposure occured and how persistent it was. For prospective mothers with diabetes we advise to start paying close attention to their glucose control several months before trying to get pregnant. ...Read more
Cyst is the defect: The porencephalic cyst by itself is considered a birth defect. The neurological consequence of the cyst, the hemiplegia is more a side effect than a birth defect. This is similar to the lower limb paralysis that would be expected with an open spine defect -spina bifida. In both cases, function of normal nerves is distorted or lost due to the defect. ...Read more
Renal failure.: Oligohydramnios, due to decreased fetal renal function, may lead to fetal lung hypoplasia and skeletal malformations. Use is associated with anuria, hypotension, renal failure, skull hypoplasia, and death in the fetus/neonate. The exposed fetus should be monitored for fetal growth, amniotic fluid volume, and organ formation. Infants exposed should be checked for hyperkalemia, hypotension, oliguria. ...Read more