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Doctor insights on: Familial Pattern Of Pulmonary Hypertension

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Is pulmonary hypertension hereditary?

Is pulmonary hypertension hereditary?

It may be inherited: Up to 5% of patients with pulmonary arterial hypertension (pah) may have a genetic or heritable cause. Research studies have identified a genetic abnormality affecting bone morphogenetic protein receptor 2 (bmpr2) that appears to predispose a patient to pah. Fortunately, even if an individual inherits the abnormal gene, the likelihood of developing pah is only 1 in 5. ...Read more

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Dr. Michael Kleerekoper
324 doctors shared insights

Hypertension (Definition)

A blood pressure reading has two numbers: a systolic blood pressure and a diastolic blood pressure. The systolic blood pressure is the maximum pressure the blood exerts on the vessels when the heart is beating. The diastolic blood pressure is the pressure the blood exerts on the vessels in between heartbeats. Hypertension, or high blood pressure, begins when the systolic blood pressure remains above 140 or when the diastolic blood pressure remains above 90. Hypertension can be a result of increased blood flow through vessels or increased resistance to ...Read more


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Stages of pulmonary hypertension?

Stages of pulmonary hypertension?

PH Stages: There are not any specific stages of pulmonary hypertension (ph); however, one of the several ways your doctor determines the severity of the ph is by assessing your symptoms using the new york heart association (nyha) score from 1 to 4.. Four is the worse and typically involves shortness of breath at rest. ...Read more

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Is pulmonary hypertension a hereditary condition?

Is pulmonary hypertension a hereditary condition?

It may be inherited: Up to 5% of patients with pulmonary arterial hypertension (pah) may have a genetic or heritable cause. Research studies have identified a genetic abnormality affecting bone morphogenetic protein receptor 2 (bmpr2) that appears to predispose a patient to pah. Fortunately, even if an individual inherits the abnormal gene, the likelihood of developing pah is only 1 in 5. ...Read more

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Renal hypertension is a form of secondary hypertension. Right?

Renal hypertension is a form of secondary hypertension. Right?

Yes: Many renal diseases, e.g., renal artery stenosis, chronic pyelo- or glomerulo- nephritis, radiation injury and some tumors can cause hypertension. ...Read more

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Is pulmonary hypertension hereditable?

Yes: If you have primary pulmonary hypertension there are several classes of drugs to treat it. Tracleer, (bosentan) revatio, letaris are some of the drugs that can be used in the right situation. ...Read more

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What. Is antihypertensive of choice in interstitial lung disease with mild pulmonary hypertension?

What. Is antihypertensive of choice in interstitial lung disease with mild pulmonary hypertension?

Several choices: In the absence of other heart problems i would tend to try amlodipine in someone with high blood pressure and mild pulmonary hypertension. However many other medications such as acei or arb, beta blockers, Diltiazem or diuretics could also be appropriate. Please discuss with your doctor. ...Read more

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Is pulmonary hypertension always present in atrial septal defect?

Is pulmonary hypertension always present in atrial septal defect?

No: People with asds do not always have pulmonary hypertension. An untreated ASD can potentially lead to pulmonary hypertension over a long period of time. But it's not always present. ...Read more

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Is pulmonary hypertension always associated with heart failure?

Is pulmonary hypertension always associated with heart failure?

No: Only when the pulmonary hypertension causes the right ventricle to dilate (enlarge) does heart failure occur. This type of failure may affect the right side of the heart causing increased leg swelling, fluid buildup in the abdomen and elevation of liver enzymes. If the swelling of the right heart becomes severe it can affect the function of the left side of the heart and cause pulmonary edema. ...Read more

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Are vascular conditions a common complication of pulmonary hypertension?

No: Complications of pulmonary HTN include acute right heart failure insitu pulmonary clots and eventual refractory respiratory failure. This is related to progressive pulmonary artery narrowing, which is a hallmark of the disease not a complication of it. ...Read more

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Pulmonary hypertension with lung pressure of 48 is that treatable and considered mild?

Pulmonary hypertension with lung pressure of 48 is that treatable and considered mild?

Mild PH: Pulmonary hypertension (ph) is often first detected by echocardiogram which estimates the pulmonary artery systolic pressure. The diagnosis is confirmed by right heart catheterization which measures mean pulmonary artery pressure and resistance. I don't know which pressure you are referencing. Nonetheless, you need to discuss the significance with your physician. ...Read more

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What is the significance of cardiomegaly with pulmonary congestive changes?

What is the significance of cardiomegaly with pulmonary congestive changes?

Concerned: Sounds like symptoms of a failing heart.Are 20? Do you have congenital heart disease? The possibility of viral myocarditis at this time of also exists.Whatever your age i hope you are under a doctors care. ...Read more

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What dot ventricular hypertrophy, and familial hypercholesterolemia mean?

What dot ventricular hypertrophy, and familial hypercholesterolemia mean?

Two separate : Entities. Ventricular hypertrophy and hypercholesterolemia are usually not related. Hyper-cholestrolemia causes heart disease and ventricular hypertrophy may end up in heart failure. Please be more specific in your question. ...Read more

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Is pulmonary hypertension an inherited disease?

Is pulmonary hypertension an inherited disease?

Sometimes: There are some forms of pulmonary HTN that are inherited and there are some conditions that lead to pul HTN that are inherited but there are also forms of pul HTN that are not inherited. ...Read more

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What are the symptoms of idiopathic pulmonary hypertension?

What are the symptoms of idiopathic pulmonary  hypertension?

PH symptoms: High blood pressure in the lungs is called pulmonary hypertension (ph) or pulmonary arterial hypertension (pah). Idiopathic pah has no known cause. Symptoms are non-specific and often include shortness of breath, chest discomfort, light headedness, and even exertional fainting. ...Read more

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Artrial septial defect with pulmonary hypertension in children?

Artrial septial defect with pulmonary hypertension in children?

Talk to MD: As long as there is no reversal of flow which can happen soon due to pulmonary hypertension, a surgical repair may be beneficial. The answer should be given by a cardiologist. Talk to the cardiologist please for your child's sake. Good luck. ...Read more

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Does a right atrium dilated, RV pressure of 25-30 mHg, IVC dynamics 5-10 mmHg subjective possibly of pulmonary hypertension or heart failure?

Does a right atrium dilated, RV pressure of 25-30 mHg, IVC dynamics 5-10 mmHg subjective possibly of pulmonary hypertension or heart failure?

If accurate, only: mildly ?ed. RA ~10 mmHg, RV systolic ~25 mmg Hg generally ~optimally healthy; similar to the values stated. Thus RA enlargement likely: mismeasurement (common, not rare; study image data yourself), marked tricuspid regurgitation, congenital variant, atrial muscle problem [eg advanced arterial disease in RA arteries; (lumens too small to see by angiography) producing RA ischemia/fibrosis], etc. ...Read more

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Is there any new recommendations regarding hypertension and pre hypertension in people with definite coronary artery disease?

Is there any new recommendations  regarding hypertension and pre hypertension in people with definite coronary artery disease?

For younger: men <60, the recommendation is stricter blood pressure control <= 120/80 with beta blocker, thiazide diuretic and/or ACE inhibitor or ARB. For older folks the current recommended pressure threshold is <= 130/85 but that recommendation could change within the next 2 years. Salt restriction to less than 2000 mg daily is also recommended along with cardiovascular exercises daily. ...Read more

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What type of anemia is associated withportal hypertension?

What type of anemia is associated withportal hypertension?

Hypersplenism: Portal Hypertension causes backup of blood in splenic area & this tends to cause hypersplenism where platelets & blood cells are sequestered. Portal hyper-tension also inhibits ability of liver to make clotting factors which may lead to increased Gastrointestinal bleeding. Portal Hypertension is sometimes associated with B12 & Folate (folic acid) deficiency. Medications used to treat may cause IV Hemolysis. ...Read more

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Would pulmonary hypertension cause a restrictive pattern on spirometry (fvc = 50% of expected for age).

Would pulmonary hypertension cause a restrictive pattern on spirometry (fvc = 50% of expected for age).

The other way around: Can be the case, as in restrictive lung disease leading to pulmonary hypertension. But in your case, where it is suspected to be a neuromuscular form of lung disease, this much less commonly leads to pulmonary hypertension than other restrictive causes like pulmonary fibrosis ...Read more

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What's pulmonary hypertension?

What's pulmonary hypertension?

High BP in the lung: The pressure in the blood vessels of the lung is increased in pulmonary htn. Causes can include heart disease, disease of the lung and primary disease of the blood vessel of the lung. The symptoms are mainly shortness of breath but can also include chest pain and dizziness. The disease can go unrecognized for some time before its diagnosed. ...Read more

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What is pulmonary hypertension?

What is pulmonary hypertension?

See below: Normal pulmonary artery pressure (pap) in a person living at sea level has mean value of 12-16 mm of hg.Pulmonary hypertension is present when mean pa pressure is above25 mm of hg at rest or 30 mm of hg with exercise! ...Read more

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Stages of pulmonary hypertension?

PH Stages: There are not any specific stages of pulmonary hypertension (ph); however, one of the several ways your doctor determines the severity of the ph is by assessing your symptoms using the new york heart association (nyha) score from 1 to 4.. Four is the worse and typically involves shortness of breath at rest. ...Read more

See 1 more doctor answer
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Is pulmonary hypertension hereditary?

It may be inherited: Up to 5% of patients with pulmonary arterial hypertension (pah) may have a genetic or heritable cause. Research studies have identified a genetic abnormality affecting bone morphogenetic protein receptor 2 (bmpr2) that appears to predispose a patient to pah. Fortunately, even if an individual inherits the abnormal gene, the likelihood of developing pah is only 1 in 5. ...Read more

See 3 more doctor answers
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Is pulmonary hypertension hereditable?

Yes: If you have primary pulmonary hypertension there are several classes of drugs to treat it. Tracleer, (bosentan) revatio, letaris are some of the drugs that can be used in the right situation. ...Read more

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What exactly is pulmonary hypertension?

What exactly is pulmonary hypertension?

High BP in the lungs: High blood pressure (BP) in the lungs is called pulmonary hypertension (ph) or pulmonary arterial hypertension (pah). Pah is a chronic and life-changing disease that can lead to right heart failure if left untreated. ...Read more

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Can pulmonary hypertension be reversed?

Possibly: FDA approved treatments include oral, inhaled and infusion medications. These treatments widen lung blood vessels and ease the symptoms of Pulmonary Arterial Hypertension (PAH). ...Read more

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Can children get pulmonary hypertension?

Yes: Sometimes there are congenital cardiac defects that can cause pulmonary hypertension even in newborns. While rare, a pulmonary embolism can cause acquired pah in a child. Primary pah can occur in the teen years. Secondary pH can occur with lung diseases such as cystic fibrosis. ...Read more

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How do you treat ?Pulmonary hypertension?

Depends on the cause: Pulmonary hypertension can be caused by a large variety of illnesses - chief amongst them heart failure and chronic respiratory disease. These are best treated by treating the underlying illness - sometime if ph is caused in isolation or from more exotic entities like scleroderma or pulmonary embolism the correct treatment is surgery or medications directed at relaxing the pulmonary vasculature. ...Read more

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Is pulmonary hypertension acquired disease?

Is pulmonary hypertension acquired disease?

Generally yes: Usually, it is acquired; however, up to 5% of patients with pulmonary arterial hypertension (PAH) may have a genetic or heritable cause. ...Read more

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Looking for expert on pulmonary hypertension?

Tertiary care center: Most pulmonary hypertension experts are in tertiary medical/academic medical centers. Ideally you want to find a pah center of excellence in your state or area. ...Read more

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What are the tests for pulmonary hypertension?

What are the tests for pulmonary hypertension?

PH evaluation: The conclusive diagnostic test for PAH is a right heart catheterization to measure pulmonary artery pressures and cardiac output. The diagnosis may be supported by physical findings, blood tests, chest x-rays, electrocardiograms, echocardiograms, pulmonary function tests, exercise tolerance tests (six-minute walk tests) and nuclear scans (ventilation/perfusion scan), but these tests may be negative or only suggestive of the diagnosis. ...Read more

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What are the stages of pulmonary hypertension?

PH Stages: Pulmonary hypertension (ph) does not have stages; however, the symptoms are often graded using a functional class system. Class i is little to no symptoms all the way to class IV which includes shortness of breath at rest and right heart failure. ...Read more

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What does severe pulmonary hypertension means?

Very high pressure: "severe pulmonary hypertension" means that the blood pressure in the lungs is very high. This is different than "systemic hypertension, " which is high blood pressure in the vessels of the body. The concept, however, is the same. There are a number of causes of this pulmonary hypertension, and when very severe, it can cause significant disease. This should be followed closely by a specialist. ...Read more

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What are the effects of pulmonary hypertension?

What are the effects of pulmonary hypertension?

PH symptoms: High blood pressure in the lungs is called pulmonary hypertension (ph) or pulmonary arterial hypertension (pah). Idiopathic pah has no known cause. Symptoms are non-specific and often include shortness of breath, chest discomfort, light headedness, and even exertional fainting. ...Read more

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Is pulmonary hypertension a permanent condition?

Pulmonary HTN: In many cases, pulmonary hypertension is irreversible. Treatment options are limited especially when there is no clear cause. In other cases, such as pulmonary emboli, it is reversible with proper treatment and some time. It truly depends on the cause of pulmonary hypertension. ...Read more

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Is pulmonary hypertension a hereditary condition?

It may be inherited: Up to 5% of patients with pulmonary arterial hypertension (pah) may have a genetic or heritable cause. Research studies have identified a genetic abnormality affecting bone morphogenetic protein receptor 2 (bmpr2) that appears to predispose a patient to pah. Fortunately, even if an individual inherits the abnormal gene, the likelihood of developing pah is only 1 in 5. ...Read more

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Could you give me info on pulmonary hypertension?

Could you give me info on pulmonary hypertension?

Narrower question: Could you narrow this down a little - whole books are written on the topic. We'd be glad to try to address a specific concern. ...Read more

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Could hypertension lead to pulmonary hypertension?

Could hypertension lead to pulmonary hypertension?

Yes: There are many causes of pulmonary hypertension and one specific cause is from left heart disease. If systemic high blood pressure (hypertension) remains untreated for a long time, it can cause consequences to the left ventricle of the heart and cause problems of relaxation or thickening. This in turn causes high pressure in the left side of the heart and ultimately backup of blood and Pulm Hyptn. ...Read more

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Dr. Payam Mehranpour
2,107 doctors shared insights

Hypertension (Definition)

Hypertension is defined as elevated blood pressure systolic over 140 and diastolic over ...Read more


Dr. Charles Burger
316 doctors shared insights

Pulmonary Hypertension (Definition)

Elevated blood pressure in the lungs that can be a primary problem or ...Read more