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Doctor insights on: Familial Hypercalcemia

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Dr. Charles A Bryant
51 doctors shared insights

High Calcium Levels In Blood (Definition)

Defining a high level depends on the normal range of the laboratory measuring the calcium level. There is variability. Commonly a high value is greater than 10.5 mg/dl. However some patients may have fluctuating values ...Read more


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How is familial adenomatous polyposis inherited?

How is familial adenomatous polyposis inherited?

Autosomal dominant: Enter omim in your browser and go to the database of all inherited diseases. Autosomal dominant means that affected individuals have one normal and one abnormal gene copy, the abnormal one dominating to cause disease. An affected person has a 50% chance to pass on the abnormal gene and fap with each pregnancy. ...Read more

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How is familial adenomatous polyposis inherited?

How is familial adenomatous polyposis inherited?

Autosomal Dominant: Fap is inherited in an autosomal dominant fashion. This means that if one parent has the gene, and the other parent doesn't, each child has a 50% chance of receiving the gene for fap. The disease causes hundreds of polyps to form in the colon (see the picture), leading to colon cancer. ...Read more

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Is adrenal insufficiency hereditary?

Is adrenal insufficiency hereditary?

It can be.: One cause of adrenal insufficiency, addison's disease, is an auto-immune disorder. The immune system mistakenly makes antibodies targeting one or more proteins in the adrenal cortex, and winds up destroying the adrenal cortex, so that the adrenals can no longer make cortisol, or other hormones. As is true for most auto-immune disorders, a tendency to develop addison's can run in families. ...Read more

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Is addison's disease genetic?

Is addison's disease genetic?

Not usually: The leading causes of Addison' disease in the US are: autoimmune; metastatic cancer; bleeding into adrenal glands; infectious infiltration (such as tuberculosis). Only the autoimmune type may possibly run in families, whose members typically have other autoimmune disorders such as type 1 diabetes, hypothyroidism, vitiligo, pernicious anemia, or myasthenia gravis, to name a few. ...Read more

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How's fatal familial insomnia inherited?

How's fatal familial insomnia inherited?

Autosomal dominant : Transmission is .Autosomal dominant, meaning the gene on one of the non-sex chromosomes is always expressed, even if only one copy is present. ...Read more

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What is hereditary non-polyposis colorectal cancer (hnpcc) vs familial adenomatous polyposis (fap)?

What is hereditary non-polyposis colorectal cancer (hnpcc) vs familial adenomatous polyposis (fap)?

Both inherited: In fap presents as colonic polyps ( gardners syn will have other tumors ) , autosomal recessive due to mutations in gate keeper, tumor suppres gene. On the contrary hnpcc or lynch syndrome. Is autosomal dominant, due to dna mismatch in repair, associated with other cancers of stomach, endomet. Ca, ovary, brain, skin etc. ...Read more

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Is nephrotic syndrome hereditary?

Is nephrotic syndrome hereditary?

See below: Some causes of nephrotic syndrome are due to herediary causes, eg one of the causes of fsgs also called focal and segmentalglomerulosclerosis. ...Read more

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Is hyperthyroidism hereditary?

Is hyperthyroidism hereditary?

Partly: Genetic factors increase susceptibility to grave's disease, but a specific gene has not been identified. ...Read more

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Is acromegaly hereditary?

Is acromegaly hereditary?

Acromegaly: That would be an extremely rare situation, to my knowledge there are no hereditary links in acromegaly. ...Read more

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Is addisons disease a genetic hereditary problem?

Is addisons disease a genetic hereditary problem?

Addisions is genetic: In 2012 the answer is usually yes. Tuberculosis caused dr. Addison to describe the condition. Now it is any failure of the adrenal glands. Today it does run in families where autoimmune diseases occur. (thyroid, diabetes, adrenal, celiac, etc). ...Read more

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What genetic syndromes associated with congenital hydronephrosis ?

What genetic syndromes associated with congenital hydronephrosis ?

Genetics : There are many causes of hydronephrosis. Often hydronephrosis is found on prenatal ultrasounds but is not seen on postnatal ultrasounds. Any kidney or bladder malformation can cause hydronephrosis. In infants, posterior urethral valves, kidney stones, cystic kidneys, abdminal masses or any stenosis of the urethra or ureters may cause hydronephrosis. ...Read more

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Is kidney cancer hereditary?

Is kidney cancer hereditary?

Sometimes: The vast majority of kidney cancer cases are not inherited (sporadic). There are a handful of syndromes known to be associated with different types of kidney cancer but they are rare. A well known example is von hippel-lindau syndrome. ...Read more

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Are parathyroid disorders hereditary?

Are parathyroid disorders hereditary?

Yes and no: Parathyroid disorder can occur in anyone but it could also be hereditary (that is if a family member has hyperparathyrodiism, you are at higher risk of developing the disease). There is also a condition called men (multiple endocrine neoplasm) that can increase your risk of parathyroid disease if someone in your family has it. ...Read more

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Is fanconi's anemia associated with kidney faliure ?

Is fanconi's anemia associated with kidney faliure ?

NO: No it is not associated with kidney failure, but fanconi syndrome is which is a different disorder also named after swiss pediatrician. ...Read more

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Can my heterozygotes status of congenital adrenal hyperplasia (21-Hydrolaxe deficiency, salt-wasting) explain hirsurtism & symptoms like polydipsia?

Can my heterozygotes status of congenital adrenal hyperplasia (21-Hydrolaxe deficiency, salt-wasting) explain hirsurtism & symptoms like polydipsia?

Maybe: Hydroxylase deficiency is actually a continuum, and there are many alleles. A workup is probably not worthwhile. Manage unwanted body hair with electrolysis or lasers -- you're doing yourself a favor. If your urinalysis (chemical, sediment), renal functions (BUN, creatinine) and concentrating ability (SG >1.020) while thirsty) are normal, I would not recommend further studies. ...Read more

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Can late onset congenital hyperplasia cause addison's disease?

Can late onset congenital hyperplasia cause addison's disease?

Not really: Addison's disease is adrenal cortical failure due to injury, ablation or autoimmune disorders of adrenal gland or pituitary gland under-production of acth occurring in all genders & ages. Cah occurs mostly in ashkenazi jews, occurs in women in early to mid-adulthood & results in overproduction of androgens (male hormones). These are different disorders. See: http://www.Nadf.Us/diseases/cah.Htm. ...Read more

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What's familial dysalbuminaemic hyperthyroxinaemia?

See details: This is a mutation in the human albumen gene which causes tests for thyroid function to be falsely elevated when thyroid function is really normal. ...Read more

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Is hypothyroidism hereditary?

Is hypothyroidism hereditary?

Sometimes: Depends on the cause of your hypothyroidism. Congenital hypothyroidism (since birth) is less hereditable than acquired (latter in life) hypothyridism. ...Read more

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