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Doctor insights on: Familial Adenomatous Polyposis

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Dr. Allen Kamrava
34 doctors shared insights

Familial Adenomatous Polyposis (Overview)

Hereditary condition characterized by multiple polyps in colon which are neoplastic and have the potential for malignancy.


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Is it bad to have familial adenomatous polyposis at the age of 49?

Is it bad to have familial adenomatous polyposis at the age of 49?

R/O colon cancer etc: Fap is an autosomal dominant --presented with 100's adenomatous colorectal polyps. In the classic fap- the risk for colorectal cancer is 100% by the time you reach 45Y.O. In adidition, there is also increased risk for duodenal, stomach, thyroid, CNS cancer.Colectomy is recommended to reduce your risk. Upper endoscopy is also recommended. You should see a surgeon re-colectomy-and genetic counsellor. ...Read more

Dr. Allen Kamrava
34 doctors shared insights

Familial Adenomatous Polyposis (Overview)

Hereditary condition characterized by multiple polyps in colon which are neoplastic and have the potential for malignancy.


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What is the treatment for familial adenomatous polyposis?

Colon resection: Confirming the diagnosis, usually total colectmy required, ( to rule out extra colonic tumors as in gardner syn. ). ...Read more

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How is familial adenomatous polyposis inherited?

How is familial adenomatous polyposis inherited?

Autosomal dominant: Enter omim in your browser and go to the database of all inherited diseases. Autosomal dominant means that affected individuals have one normal and one abnormal gene copy, the abnormal one dominating to cause disease. An affected person has a 50% chance to pass on the abnormal gene and fap with each pregnancy. ...Read more

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How is familial adenomatous polyposis inherited?

Autosomal Dominant: Fap is inherited in an autosomal dominant fashion. This means that if one parent has the gene, and the other parent doesn't, each child has a 50% chance of receiving the gene for fap. The disease causes hundreds of polyps to form in the colon (see the picture), leading to colon cancer. ...Read more

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Is it bad to have familial adenomatous polyposis at the age of 49?

R/O colon cancer etc: Fap is an autosomal dominant --presented with 100's adenomatous colorectal polyps. In the classic fap- the risk for colorectal cancer is 100% by the time you reach 45Y.O. In adidition, there is also increased risk for duodenal, stomach, thyroid, CNS cancer.Colectomy is recommended to reduce your risk. Upper endoscopy is also recommended. You should see a surgeon re-colectomy-and genetic counsellor. ...Read more

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What is the definition or description of: familial adenomatous polyposis?

What is the definition or description of: familial adenomatous polyposis?

Hereditary condition: Hereditary condition characterized by multiple polyps in colon which are neoplastic and have the potential for malignancy. ...Read more

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Familial adenomatous polyposis - is it transmissible to everyone in the family?

50%: If one parent has the condition, approximately 50% of the children will have it. This is an autosomal dominant pattern of heredity. ...Read more

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Has anyone heard of fap (familial adenomatous polyposis) outside the amish community?

Has anyone heard of fap (familial adenomatous polyposis) outside the amish community?

Yes sure: Fap occurs in approximately 1/10, 000 to 1/30, 000 live births, and accounts for less than 1 % of the total colon cancer risk in the United States it happens not only in amish community- but also in other population- such as in ashkenazi jewish population for instance, etc. ...Read more

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Does familial adenomatous polyposis affect the whole colon?

Yes: Requires surgery. True fap is almost uniformly fatal by age 50. ...Read more

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Can familial adenomatous polyposis affect the whole of the colon?

It can: Also impact on other parts of the GI tract including the duodenum. This inherited disorder also is associated with abdominal desmoid tumors. ...Read more

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Familial adenomatous polyposis--how often does it progress to cancer?

Familial adenomatous polyposis--how often does it progress to cancer?

Polyposis: The risk of colon cancer is eight times higher in patients with familial polyposis than the general population. ...Read more

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I'm having constipation, could it be familial adenomatous polyposis and what are the other symptoms?

I'm having constipation, could it be familial adenomatous polyposis and what are the other symptoms?

Constipation can : Occur without the familial adenomatosis. If you feel you are at risk for fap, you need to see a GI or colon and rectal surgeon and get a colonoscopy. Only then can your constipation be addressed properly. ...Read more

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I had a colonoscopy at 18 due to pain, bleeding they found four polyps, one being a fap (familial adenomatous polyposis) why only one? More in future?

I had a colonoscopy at 18 due to pain, bleeding they found four polyps, one being a fap (familial adenomatous polyposis) why only one? More in future?

Fap: FAP: it means that you have a disease that runs in the family, which makes you prone to making a lot of polyps at a young age. Some of those can turn into cancer in the future. All your polyps are probably due to FAP. You need regular colonoscopies to screen for new polyps. ...Read more

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Is it still possible for me to have familial adenomatous polyposis if parent had colon cancer?

Is it still possible for me to have familial adenomatous polyposis if parent had colon cancer?

Yes if parent has it: Yes if parent had colon cancer due to familial adenomatous polyposis, you could have inherited, only way to rule out is to see your physician , and have a colonascopy done. ...Read more

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What is hereditary non-polyposis colorectal cancer (hnpcc) vs familial adenomatous polyposis (fap)?

What is hereditary non-polyposis colorectal cancer (hnpcc) vs familial adenomatous polyposis (fap)?

Both inherited: In fap presents as colonic polyps ( gardners syn will have other tumors ) , autosomal recessive due to mutations in gate keeper, tumor suppres gene. On the contrary hnpcc or lynch syndrome. Is autosomal dominant, due to dna mismatch in repair, associated with other cancers of stomach, endomet. Ca, ovary, brain, skin etc. ...Read more

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What is the treatment for familial adenomatous polyposis?

Colon resection: Confirming the diagnosis, usually total colectmy required, ( to rule out extra colonic tumors as in gardner syn. ). ...Read more

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Is there a treatment for familial polyposis?

Is there a treatment for familial polyposis?

FAP IS AN INHERITED: Condition in which numerous polyps form throughout the bowel. If you have a few, they can be endoscopically remomed. However, with time they become too numerous to treat this way individually. To prevent cancer, surgery is indicated, usually late teens to early 20's. But remember, these polyps can reccur throughout your stomach, snall and large bowels so close surveillance is definitely a must. ...Read more

Dr. Murthy Andavolu
1,349 doctors shared insights

Adenoma (Definition)

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